yeast

This paper uses Hi-C data to infer 3D genome structure and chromatin dynamics in budding yeast without prior assumptions about nuclear organization.

The paper predicts a cohesin acetylation complex in budding yeast that interacts with nicked DNA and confirms its function through experiments.

This study shows that yeast Gcn2 promotes P-body formation through eIF2α phosphorylation and Smu2-dependent mRNA granule maturation, even when eIF2α phosphorylation is blocked.

This study shows that Mto1 and Mto2 stabilize γ-tubulin positions in fission yeast γ-TuRCs, enabling microtubule nucleation through structural modulation.

This study reveals how mitochondrial complex III assembles from preformed matrix domain modules, showing dynamic subunit exchange and the role of specific residues in assembly and disease.

The paper shows that FACT facilitates Ubp10 release from nucleosomes after H2B deubiquitination, revealing release as the rate-limiting step for Ubp10 turnover.

This study identifies three distinct pathways maintaining kinetochore integrity during meiosis in budding yeast, with distinct temporal requirements and interactions involving Ctf19cCCAN, Mif2CENP-C, and Cse4CENP-A-Okp1CENP-Q-Ame1CENP-U.

This study identifies extensive horizontal gene transfer in the fungus gnat Bradysia coprophila, showing these genes contribute to stress tolerance and ecological adaptation.

The paper uses R-DeeP to show stress-induced compartment-specific RNA buffering of protein aggregation in yeast, with nuclear RNA retention protecting nuclear proteins from aggregation.

The paper identifies widespread Saccharomyces hybridization in agave fermentations, showing multiple independent origins and asymmetric parental genetic diversity.

The paper develops a pipeline to collect, characterize, and scale wild yeast for beer brewing, identifying interventions to overcome industrial fermentation challenges.

This study shows that evolution can restore cellular function without conserving microscopic organization, leading to novel molecular phenotypes in budding yeast.

This paper introduces two methods, SLED and GTD, to infer modular structure in genotype-phenotype maps by combining epistasis and pleiotropy, showing they yield similar modular architectures in yeast data.

The paper uses computational methods to analyze antioxidant effects on stress response mechanisms in Candida albicans, identifying naringenin and quercetin as potential modulators of Sir2/SIRT3 pathways.

This study shows that non-homologous end joining (NHEJ) facilitates rapid adaptation to caspofungin in Nakaseomyces glabratus by enabling FKS2 mutations, while NHEJ-deficient strains adapt less efficiently through alternative pathways.

GOParsimony filters GO terms to identify the most parsimonious functional annotations for gene/protein sets, outperforming existing methods in yeast and human data.

This paper develops a tunable auxin-based trans-kingdom signaling system that enables cross-species communication by engineering auxin biosynthesis and response mechanisms in different organisms.

This study engineers Saccharomyces cerevisiae to produce polyphosphate more efficiently by modifying metabolic pathways and growth conditions.

The paper investigates the mcm4Chaos3 mutation in yeast, showing it causes genome instability by impairing specific centromere-proximal origins.

This study identifies structural features of Hmg2 that mediate GGPP-dependent misfolding and regulation, revealing that GGPP binding occurs in the transmembrane domain and loops in the lumenal domain transmit the response.

This study investigates coenzyme specificity in yeast GDH3, showing how mutations alter coenzyme preference and revealing structural and evolutionary mechanisms of coenzyme regulation.

This study uses biosensor-guided CRISPR screens in yeast to identify genetic targets that enhance production of cis,cis-muconic acid and protocatechuic acid.

This study shows that Lac1-dependent ceramide synthesis is essential for proper septum assembly and cell separation in fission yeast.