Advanced MRI Techniques and Applications

Iterative delay correction improves breath-hold cerebrovascular reactivity mapping in clinical populations

This paper introduces an iterative delay correction method to improve breath-hold cerebrovascular reactivity mapping in clinical populations by adjusting the temporal search range for each voxel.

Pooling quantitative MRI data: A multi-protocol study of healthy subcortical ageing

This study evaluates how protocol and hardware differences affect pooling quantitative MRI data across sites in healthy aging studies, finding both benefits and drawbacks for analysis outcomes.

Blood volume sensitive laminar fMRI with VASO in human hippocampus: Capabilities and biophysical challenges at clinical 7T scanners

This study optimizes VASO for submillimeter laminar fMRI in the human hippocampus, enabling differentiation of neural activity from vein bias in memory tasks.

Laminar CBV and BOLD response-characteristics over time and space in the human primary somatosensory cortex at 7T

This study characterizes laminar BOLD and VASO responses to digit stimulation in human somatosensory cortex, revealing triphasic dynamics and potential excitation-inhibition mechanisms.

Motion-Corrected Structural Realignment and Quantitative Voxel Targeting in Magnetic Resonance Spectroscopy

This paper improves voxel targeting accuracy in MRS by correcting motion-induced displacement and quantifying anatomical targeting using a voxel-ROI overlap metric.

Processing strategies for improving cortical thickness correspondence between low-field and high-field MRI in young people

This study evaluates low-field MRI processing strategies to improve cortical thickness correspondence with high-field MRI in young people, finding that recon-all-clinical on multi-orientation T2w images provides the best results.

In vivo longitudinal mapping of brain iron accumulation after pilocarpine-induced status epilepticus

This study uses QSM to track brain iron accumulation in a pilocarpine-induced epilepsy model, finding increased iron deposits in specific brain regions over time.

Evaluating BOLD functional MRI biophysical simulation approaches: impact of vascular geometry, magnetic field calculations, and water diffusion models

This paper compares eight BOLD fMRI simulation approaches, finding that most are accurate but some are biased, with intravascular signal differences affecting results.

MICAFlow: Fast and Robust MRI Preprocessing Bridging Research Neuroimaging and Clinical Practice

MICAFlow provides a fast and robust MRI preprocessing pipeline that translates research workflows into clinical practice, achieving high registration accuracy and data reliability across diverse datasets.

Fast-cWDM Brain MRI: Fast Conditional Wavelet Diffusion Model for Synthesis Brain MRI Modality

This paper introduces a fast conditional wavelet diffusion model for synthesizing missing MRI modalities, achieving competitive performance and high segmentation accuracy.

Calibration of MRI-based reference intervals to new samples

This paper introduces ReForm, a method to calibrate MRI-based reference intervals for new samples without sharing reference data, showing comparable or better false positive rate control than alternative methods.

The Consequences of Statistical Tests on Using Proxy Measurements in Place of Gold Standard Measurements: An Application to Magnetic Resonance Spectroscopy

This paper examines how proxy measurements in magnetic resonance spectroscopy affect statistical test outcomes, showing inflated false positive and negative rates due to bias and correlation with gold-standard measurements.

The effects of elevated serum lactate on measures of apparent cerebral metabolism and perfusion in the anesthetised rodent brain.

This study investigates how elevated serum lactate affects cerebral perfusion and metabolism in anesthetized rodents using hyperpolarized 13C MRI, finding significant changes in perfusion and lactate:pyruvate ratios but not bicarbonate:pyruvate ratios.

The Hemodynamic Response Function Varies Across Anatomical Location and Pathology in the Epileptic Brain

This study identifies four distinct HRF shape groups in the epileptic brain, showing HRF variability is linked to both anatomical location and pathology.

Cross-modal quality transfer: enhancing MEG spatial resolution using BOLD-fMRI and Explainable machine learning.

This paper enhances MEG spatial resolution using BOLD-fMRI and explainable machine learning, achieving high predictive performance and detailed upsampled maps.

Investigating the variability of physiological response functions across individuals and brain regions in functional magnetic resonance imaging

This study examines how physiological response functions (PRFs) vary across individuals and brain regions in fMRI data and shows that allowing spatial and subject-specific variability improves PRF model performance.

BOLD signal changes can oppose oxygen metabolism across the human cortex

The paper shows that BOLD signal changes can oppose oxygen metabolism in 40% of voxels, particularly in the default mode network, challenging the canonical interpretation of fMRI.

MRS4Brain: a processing toolbox for preclinical MR spectroscopy and spectroscopic imaging data

MRS4Brain provides a MATLAB-based toolbox for preclinical MR spectroscopy and imaging, streamlining data processing and improving reproducibility and accessibility.

Identifying out-of-voxel echoes in edited MRS with phase cycle inversion

The paper introduces a method to identify out-of-voxel signals in MRS by analyzing phase cycles, leading to improved suppression of artifacts through optimized gradients.

Multimodal MR Imaging for quantification of brain lipid in mice at 9.4T

This study evaluates the repeatability and sensitivity of NOEMTR, tNOE, and MWF for quantifying lipid and myelin content in mouse brains, finding tNOE to be the most sensitive for detecting myelin lipids.

Hyperintense signals in cerebral blood flow maps acquired with pseudo-continuous arterial spin labeling MRI in mice

This study characterizes hyperintense signals in pCASL MRI of mice, showing they appear in arteries, veins, and ventricles, differing from humans, and identifies optimal PLD and crusher gradient settings for accurate CBF measurement.

Concurrent assessment of neurometabolism and brain hemodynamics to comprehensively characterize the functional brain response to psychotropic drugs: an S-ketamine study

This study uses combined phMRI and phMRS to assess brain responses to S-ketamine, showing dose-dependent hemodynamic and neurometabolic changes in specific brain regions.

DeepCor: Denoising fMRI Data with Contrastive Autoencoders

DeepCor improves fMRI denoising by using contrastive autoencoders, outperforming CompCor on simulated data and enhancing connectivity differences in real datasets.

Gradient scheme optimization for PRESS-localized edited MRS using weighted pathway suppression

This paper optimizes a gradient scheme for PRESS-localized edited MRS to suppress out-of-voxel artifacts using a volume-based likelihood model and genetic algorithm.

Stimulus-modulated approach to steady-state: A new paradigm for event-related fMRI.

This paper introduces a stimulus-modulated approach to steady-state in fMRI to improve sensitivity by using initial high tSNR volumes, reducing trial numbers needed for statistical thresholds.

Precision functional imaging in infants using multi-echo fMRI at 7T

This paper demonstrates that 7T MRI improves spatial resolution and data quality for functional brain mapping in infants compared to 3T MRI, enabling more reliable developmental studies.

From Peaks to Patterns

The paper develops an interactive visual analysis system for MRS signals to improve the evaluation and interpretation of metabolite data in neurological and metabolic disorders.

Paediatric MRI: High-Resolution in vivo 3T Methods

The paper develops high-resolution MRI methods for paediatric brain imaging, enabling detailed structural analysis in under nine minutes.

Test-retest reliability of multi-metabolite edited MRS at 3T using PRESS and sLASER

This study compares the test-retest reliability of HERMES and HERCULES multi-metabolite editing methods using PRESS and sLASER for volume localization in MRS.

Generalization of Optimal Control Saturation Pulse Design for Robust and High CEST Contrast

This paper develops a generalized optimal control pulse for CEST imaging that improves contrast and robustness across varying parameters and field strengths.