Memory and Neural Mechanisms

Homeostatic Binary Networks: A simple framework for learning with overlapping patterns

This paper introduces a framework called Homeostatic Binary Networks that learns to represent overlapping memory patterns through recurrent dynamics and plasticity mechanisms.

Representations in the hippocampal-entorhinal system emerge from learning sensory predictions

This paper introduces a computational model that generates diverse neural representations in the hippocampal-entorhinal system through contrastive learning, capturing spatial coding patterns observed in real neural data.

Spatial Coding Dysfunction and Network Instability in the Aging Medial Entorhinal Cortex

This study examines spatial coding dysfunction and network instability in aged medial entorhinal cortex using in vivo electrophysiology and gene expression analysis in mice.

Learning a shared vocabulary between episodic and semantic memory enhances recall and compositional consolidation

The paper proposes a computational model where semantic vocabulary is shared between episodic and semantic memory, enhancing recall and compositional consolidation through replay mechanisms.

Three types of remapping with linear decoders: a population-geometric perspective

The paper presents a framework to understand hippocampal remapping through three mechanisms using a linear decoder and population geometry perspective.

Hippocampal sequences represent working memory and implicit timing

This study investigates how hippocampal sequences represent working memory and implicit timing in a rodent task where odor identity predicts delay duration.

Sex Based Differences in Active Avoidance and Approach Strategy in the Platform Mediated Avoidance Task

This study investigates sex differences in avoidance strategies using a modified platform-mediated avoidance task in rats, finding females prioritize safety while males pursue rewards despite risk.

Neurogenesis-dependent transformation of hippocampal memory traces during systems consolidation

The paper shows that hippocampal memory resolution decreases over time, and this transformation depends on adult hippocampal neurogenesis.

Ca2+ Plateau Potentials Reflect Cross-Theta Cortico-Hippocampal Input Dynamics and Acetylcholine for Rapid Formation of Efficient Place-Cell Code

The paper investigates the cellular mechanisms of BTSP-LTP in the hippocampus, showing that theta-oscillation-paced inputs and acetylcholine modulate Ca2+ plateau potentials for efficient place-cell coding.

Hippocampal-cortical interactions in the consolidation of social memory

This study identifies specific hippocampal-cortical circuits involved in social memory consolidation using optogenetic and imaging techniques.

Encoding of interdependent features of head direction and angular head velocity in navigation

The paper investigates how neurons encode interdependent features of head direction and angular head velocity in mice, revealing distinct encoding strategies and their functional implications.

Learning induces persistent chromatin loops underlying robust gene expression during memory recall

The paper identifies persistent chromatin loops in hippocampal neurons after fear conditioning that correlate with gene expression changes during memory recall.

Diverse calcium dynamics underlie place field formation in hippocampal CA1 pyramidal cells

This study investigates the role of calcium dynamics in place field formation in hippocampal CA1 pyramidal cells using in vivo two-photon imaging in head-restrained mice.

Adolescent alcohol exposure disrupts retrosplenial cortex physiology in adult males

This study shows that adolescent alcohol exposure reduces intrinsic excitability in adult male retrosplenial cortex pyramidal cells, suggesting vulnerability in males.

Unsilenced inhibitory cortical ensemble gates remote memory retrieval

The paper identifies a subset of GABAergic neurons in the ACC that gate remote memory retrieval through persistent activity and synchronization.

The Reinstatement of a Forgotten Infantile Memory

This paper investigates how forgotten infantile memories persist in the hippocampus and can be reinstated through specific network processes involving contextual and aversive reminders.

Gustatory Thalamic Neurons Mediate Aversive Behaviors

This study shows that gustatory thalamic neurons mediate aversive behaviors by responding to noxious stimuli and fear memory, with chemogenetic and optogenetic manipulation affecting aversive responses.

An Implementation Intention Combining Reappraisal and Anger Counteraction Reduces Fear Reinstatement

This paper introduces an implementation intention combining reappraisal and anger counteraction to reduce fear reinstatement during extinction learning.

CS - plasticity and behavioral-state integration in the posterior insula during auditory fear learning

The paper identifies plastic encoding of an auditory conditioned stimulus in the posterior insula during fear learning, driven by LTP at the auditory cortex input.

Exponential Map Models as an Interpretable Framework for Generating Neural Spatial Representations

This paper introduces an exponential map framework to generate interpretable neural spatial representations, showing how algebraic conditions enable path and translational invariance and biologically relevant spatial tuning.

Corticonigral projections recruit substantia nigra pars lateralis dopaminergic neurons for auditory threat memories

The paper identifies robust corticonigral projections to substantia nigra pars lateralis dopaminergic neurons involved in auditory threat memory, contrasting with sparse cortical input to other nigral populations.

Brain-wide representational drift: memory consolidation and entropic force

This paper links microscopic neuronal representational drift to macroscopic memory consolidation using a statistical physics model, predicting engram dynamics in the mouse brain.

Extinction and subsequent updating of innate fear responses to a visual looming stimulus rely on hippocampus-dependent mechanisms

The paper shows that innate fear responses to visual looming stimuli in mice can be reduced through repeated exposure and that hippocampal engrams are required for learned fear responses.

Functional independence of entorhinal grid cell modules enables remapping in hippocampal place cells

The paper shows that differential phase shifts in grid cell modules enable hippocampal place cell remapping, suggesting a mechanism for orthogonalizing spatial codes during environmental changes.

Transcriptomic Signatures of Hippocampal Subregions and Neuronal Nuclei in Active Place Avoidance Memory Maintenance

This study identifies transcriptomic changes in hippocampal subregions and neurons during offline memory maintenance using spatial transcriptomics and snRNA-seq.

Neuronal signatures of successful one-shot memory in mid-level visual cortex

The paper identifies neuronal signatures of one-shot memory in mid-level visual cortex, showing sparse coding and population response consistency predict memory performance.

Differential functional connectivity between hippocampus and prefrontal cortex is associated with heterogeneity in open field exploration

The paper identifies two distinct behavioral modes in rats during open field exploration, showing differential functional connectivity between hippocampus and prefrontal cortex.

Unifying spatial and episodic representations in the hippocampus through flexible memory use

This paper proposes that the hippocampus's primary function is storing and retrieving episodic memories, with spatial representations emerging as a byproduct, using a computational model to demonstrate this.

Hippocampus serves as a repository for spoken and heard word meanings during conversations

The paper shows hippocampal neurons encode meanings of spoken and heard words using shared geometric embeddings, enabling abstract cross-personal representations while preserving speaker identity binding.

Not a global map, but a local hash: grid cells decorrelate the representation of position and scramble long-range distance information

The paper shows grid cells decorrelate position representations and act as a pattern separation device, similar to a hash function, enhancing episodic memory.