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A Novel GelMA-OrnMA Electrically Conductive Bioink for Developing Engineered Neural Tissues

This paper introduces a novel conductive bioink, GelMA-OrnMA, that supports astrocyte proliferation, matches native neural tissue stiffness, and provides electrical conductivity for engineered neural tissues.

Preserving Tissue Integrity Under the Beam: High-Energy, Low-Dose Synchrotron CT for in situ Imaging of Bovine Intervertebral Discs

This study shows that low-dose synchrotron CT can image bovine intervertebral discs repeatedly without damaging their mechanical, microstructural, or molecular properties.

Improving Growth Predictions in Aquaculture through an Improved Bioenergetics Model Incorporating Feed Composition and Nutrient Digestibility for Largemouth Bass (Micropterus salmoides)

This paper improves growth predictions for largemouth bass by introducing a bioenergetics model that incorporates feed composition and nutrient digestibility, showing better accuracy than traditional models.

Strengthening Antisense Oligonucleotide-Mediated Anti-Tumor Immunity via Metal-Organic Framework Nanoparticles

This study uses metal-organic framework nanoparticles to deliver antisense oligonucleotides, enhancing their stability and reducing PD-L1 expression in cancer cells.

Surface Transmon Resonance (STR): a handheld nanogap biosensor for real-time, label-free molecular binding kinetics

This paper introduces a handheld electronic biosensor, STR, that enables real-time, label-free detection of molecular interactions with performance comparable to optical biosensors.

A Systems-Level Framework Integrating Geometry-Controlled Plasmonics, AI-Driven Molecular Kinetics, and Organoid Validation for Next-Generation Biosensing

This paper introduces a systems-level framework combining plasmonic nanosensors, AI-driven molecular kinetics, and organoid validation to enhance biosensing capabilities.

Preservation Strategies for Vascularized Composite Allotransplantation: An Updated Systematic Review of a Rapidly Expanding Field

This paper reviews recent advances in vascularized composite allotransplantation preservation strategies, highlighting machine perfusion and supercooling as promising methods to extend graft viability.

An automated image analysis pipeline for wide-field optical redox imaging of patient-derived cancer organoids

The paper develops an automated image analysis pipeline for wide-field optical redox imaging of patient-derived cancer organoids, achieving high accuracy and significantly faster processing than manual methods.

Targeted shedding of extracellular membrane proteins by induced protease recruitment

This paper develops Shedders, bispecific antibodies that recruit ADAM10 to induce ectodomain shedding of cell surface proteins, demonstrating efficacy in depleting LAG-3 and identifying new targets for therapeutic intervention.

Electrical Surface Polarization as a Functionalization Strategy to Improve Bone Regeneration of Apatite-Based Graft Materials

This study shows electrical surface polarization improves bone regeneration of apatite-based grafts by enhancing osteoclast activity and implant-bone integration in vivo.

Distinct Chiral Nanostructures of Graphene Quantum Dots Govern Divergent Passive and Active Enantioselective Transport across Biological Membranes

This study investigates how chiral ligand modulated graphene quantum dots (GQDs) form distinct nanostructures that influence passive and active enantioselective transport across biological membranes.

Growth-adaptive spring electronics for long-term, same-neuron mapping in the developing rat brain

This paper introduces growth-adaptive spring electronics and a spike processing pipeline to enable long-term, same-neuron mapping in developing rat brains, revealing neuron-specific developmental decorrelation.

The Role of Glycan Structures in Modulating GM-CSF Bioactivity: Insights from Glycoengineering

This study investigates how glycan structures affect GM-CSF bioactivity by engineering glycoforms in Chinese hamster ovary cells and testing their effects on TF-1 cell proliferation.

LiverMap pipeline for 3D imaging of human liver reveals volumetric spatial dysregulation of cirrhotic vasculobiliary architecture

The paper uses 3D imaging to analyze human liver tissue and identifies spatial dysregulation in cirrhotic vasculobiliary architecture.

3D, multi-omic imaging reveals molecular biomarkers of the pre-metastatic niche in lung cancer

This study uses 3D multi-omic imaging to identify biomarkers of the pre-metastatic niche in lung cancer, revealing myeloid and senescent cell signatures associated with metastasis risk.

Iliac vein morphology and wall shear stress: a statistical shape modelling and CFD analysis of patient-specific geometries

This study compares how different levels of anatomical detail in venous models affect haemodynamic risk metrics using statistical shape modelling and CFD.

Mechano-activation of synovial fibroblasts and macrophages during OA progression in the dynamically stiffening synovial microenvironment

This study investigates how synovial microenvironment stiffness changes during OA progression and how it affects fibroblast and macrophage behavior through mechanosignaling and cell-cell interactions.

Radiotherapy Enhancement by Gold Nanocluster-functionalized Nanoliposomes Using Polychromatic Orthovoltage X-ray Irradiation

This study evaluates gold nanocluster-functionalized nanoliposomes under orthovoltage X-ray irradiation for enhanced radiotherapy in pancreatic cancer, showing increased reactive oxygen species but challenges in formulation.

A NOVEL DEEP LEARNING MODEL, RDBCYCYLEGAN-CBAM FOR LOW-DOSE CT IMAGE DENOISING

This paper introduces RDBCycleGAN-CBAM, a deep learning model for low-dose CT image denoising, achieving higher PSNR and SSIM than existing methods.

Microfluidic Agarose Microdroplets for DNA-Encoded Chemical Library Screening

This paper introduces a microfluidic agarose-droplet platform for cellular-context DNA-encoded library screening, demonstrating its effectiveness in identifying hit molecules under near-native conditions.