Henri Berger

Inactivation of CDK4/6, CDK2, and ERK in G1-phase triggers differentiation commitment

The paper shows that inactivation of CDK4/6, CDK2, and ERK in G1-phase is necessary for irreversible cell cycle exit and differentiation commitment during terminal cell differentiation.

Synthetic chromosome fusion: effects on genome structure and function

The paper synthesizes a shorter yeast chromosome and studies its fusion with other chromosomes, revealing new 3D structural interactions and Red1 binding patterns.

Resurrecting essential amino acid biosynthesis in a mammalian cell

This paper demonstrates the successful restoration of valine biosynthesis in mammalian cells by integrating synthetic pathways from E. coli, showing that ancient metabolic pathways can be reactivated in metazoans.

De novo assembly, delivery and expression of a 101 kb human gene in mouse cells

The paper describes a pipeline for de novo assembly, delivery, and expression of a 101 kb human gene in mouse cells, demonstrating functional evaluation of a full-length gene.