L. Wang

This paper introduces a nonparametric method to estimate multiple latencies in the auditory system from auditory steady-state responses using a single EEG channel.

A cocktail of neutralizing antibodies targeting SARS-CoV-2 spike protein's NTD and RBD, when used as immunogens in rabbits, elicited strong protective immune responses.

This paper develops a prediction tool for atherosclerotic plaque progression using patient-specific multi-physical modeling and microenvironmental indicators to differentiate stable from unstable plaques.

This study shows baricitinib reduces lung inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques without affecting viral shedding or immune responses.

This paper introduces a hierarchical 3D-motion learning framework to map animal spontaneous behavior by capturing kinematics and learning dynamic behavior patterns.

This study shows that RANKL from bone marrow adipocytes regulates trabecular osteoclast formation and bone loss in mice, with implications for therapeutic targeting of bone marrow adiposity.

This study establishes a murine model of COVID-19 using MHV-A59 and shows that type-I interferons limit viral dissemination, reducing lethality and recapitulating key clinical features.

This study uses multi-region single-cell sequencing to map the spatial and cellular architecture of early-stage lung adenocarcinoma, revealing geospatial lineage evolution and potential therapeutic targets.

This study analyzes single-cell RNA and TCR profiles from AML patients before and after PD-1 blockade therapy to identify factors influencing response and resistance.

This study induces bipedal posture in mice to create a model of lumbar ligamentum flavum hypertrophy and shows increased stress leads to degeneration.

This study identifies Dhx36 as essential for skeletal muscle stem cell regeneration by regulating mRNA translation through binding and unwinding 5' UTR G-quadruplex structures.

This study uses single-cell RNA-seq and TCR sequencing to analyze CMV-reactivated CD4+ T cell subsets, revealing their heterogeneity, functional roles, and interactions.

This study identifies an epigenetic vulnerability in PI3K/AKT inhibitor-resistant cancers, showing that targeting bromodomain or HDAC inhibitors can overcome resistance by modulating histone acetylation at growth factor/receptor gene loci.

This study constructs a single-cell atlas of liver cancer tumor clonality using machine learning and identifies osteopontin as a key driver of tumor evolution and immune reprogramming.

This study shows that whey protein from human and other animal milk inhibits SARS-CoV-2 and GX_P2V in vitro by blocking viral attachment, entry, and replication.

The paper identifies a Rubisco-binding motif that targets proteins to the pyrenoid and maintains its three sub-compartments.

This paper reports the first known natural SARS-CoV-2 transmission from humans to animals in the USA, documenting clinical signs, diagnostic findings, and prolonged fecal RNA shedding in tigers and lions.

This paper develops membrane nanoparticles from ACE2-rich cells that effectively block SARS-CoV-2 infection by trapping the viral S1 protein and inhibiting its interaction with host cells.

This study evaluates three fecal immunoassay technologies for detecting canine Echinococcus infection in China, finding that sensitivity is lower than expected and further development is needed.

This study investigates how posture affects intestinal absorption of glucose and fat by comparing plasma insulin curves in different positions in rats.

This paper shows that HBV uses aerobic glycolysis to support its biosynthesis by interacting with PKM2, and that restoring PKM2 activity can reduce viral production and oncogenesis.

This study shows an inactivated SARS-CoV-2 vaccine induces neutralizing antibodies and CTL responses in rhesus macaques, effectively preventing viral replication and lung inflammation.

This study introduces a non-invasive imaging method to quantitatively track tumor growth in living mice, finding that tumor volume is not well correlated with cell quantity.

This study identifies molecular parallelism in highland maize landraces, showing convergent adaptation through shared SNPs, genes, and pathways related to flowering time.

This study shows that encapsulating human mesenchymal stromal cells in alginate microcapsules modulates their paracrine signaling and improves therapeutic outcomes in established osteoarthritis.

The paper shows that susceptible Pi-ta alleles are retained due to their fitness benefit by acting as an off-switch for immune signaling.

The paper identifies extracellular vesicle proteins from Schistosoma haematobium and shows that vaccinating mice with recombinant tetraspanins reduces egg burdens in a heterologous schistosomiasis model.

The paper reports the first natural SARS-CoV-2 infections in tigers and lions at the Bronx Zoo, identifying two distinct viral strains and suggesting human-to-animal transmission.

This study identifies a Vitamin D-driven mechanism that suppresses excessive Th1 responses in COVID-19, suggesting potential therapeutic use of Vitamin D analogs.

HiFi-SIM improves structured illumination microscopy image fidelity by reducing artifacts and enhancing axial resolution without requiring precise PSF calibration or parameter tuning.