M. Wang

The paper identifies two small proteins, MHA1 and MHA1L, that modulate ACD6 activity in Arabidopsis thaliana, affecting growth and defense trade-offs through calcium influx regulation.

This study evaluates the neutralization resistance of SARS-CoV-2 variants B.1.1.7 and B.1.351 to monoclonal antibodies and sera, finding increased resistance in B.1.351.

The paper compares the tumor-repressing effects of TCF11 and Nrf1, showing TCF11 is more potent, while both have similar regulatory profiles distinct from Nrf2.

The paper reports the crystal structure of bromide-bound GtACR1, showing structural changes that relax constrictions in the anion tunnel, indicating a transition to a pre-activated state.

This study characterizes the dynamic changes in B-cell receptor repertoires of COVID-19 patients using next-generation sequencing, revealing clonotype overlap, lineage expansion, and V gene usage patterns.

This study develops a high-throughput method using near-infrared spectroscopy to assess sugarcane stalk quality, achieving high prediction accuracy with RPD values up to 6.3.

This paper identifies a mutualistic interaction between non-motile Dietzia and dimorphic Glycocaulis bacteria that enables surface motility through biosurfactant-mediated mechanisms and nutrient exchange.

This study compares the early host responses to SARS-CoV-2, SARS-CoV, and MERS-CoV infections using transcriptome analysis, revealing distinct patterns of cytokine and antiviral gene expression.

The paper shows that substrate traits determine microbial community structure in metabolic division of labor by using mathematical models and synthetic consortia experiments.

This study shows osteosarcoma tumors retain transcriptional heterogeneity during bone and lung colonization despite selective pressures.

This study identifies the specific FLI regions in EWS/FLI critical for oncogenic transformation in Ewing sarcoma, showing the DNA-binding domain and a carboxyl-terminal alpha-helix are essential for transcriptional regulation and tumorigenesis.

This paper determines the cryo-EM structure of Favipiravir bound to SARS-CoV-2 polymerase, revealing its base-pairing mechanism and implications for antiviral drug development.

The paper investigates the ftin gene's role in wheat under cold stress, finding it inhibits spike development through multiple pathways and phenotypic changes.

This study investigates how MFG-E8 signaling contributes to age-related arterial damage, showing that its deficiency reduces elastolysis, fibrosis, and calcification in mice.

This study shows heat stress inhibits meiotic recombination in Arabidopsis by reducing DSB formation and homolog synapsis, affecting chromosome axis stability and recombinase levels.

This paper introduces FSEC-Nb, a method using nanobody technology to screen membrane protein expression without GFP fusion, successfully identifying ZAC orthologs and SARS-CoV-2 membrane proteins with high monodispersity.

The paper develops a shrimp aquaculture ecosystem using predatory fish to control WSSV transmission, effectively preventing outbreaks.

This study identifies SIRT5 as essential for melanoma cell survival and tumor formation, showing it regulates chromatin dynamics and gene expression through histone modifications.

BacAnt is a webserver that simultaneously annotates antibiotic resistance genes, integrons, and transposable elements in bacterial DNA sequences, generating automated genbank files.

The paper identifies public antibody clones in the human repertoire, including virus-neutralizing and anti-PD1 clones, and introduces a tool for analyzing Rep-seq data.

This study uses 3D printing to create vessel architectures that induce more physiologically relevant phenotypes in vascular smooth muscle cells compared to 2D cultures.

This study analyzes S:A ratios across species to understand dosage compensation mechanisms in sex chromosomes, finding clade-specific patterns and supporting the sex chromosome insensitivity hypothesis.

The paper compares genomes of male and female mosses to study sex chromosome evolution, finding gene-rich, non-degenerated UV sex chromosomes.

This study uses NMR spectroscopy to analyze metabolic changes in Arabidopsis seedlings treated with ES7, revealing tissue-specific metabolic alterations and disrupted homeostasis in primary metabolism.

This study identifies callose deposition as essential for cytokinesis in the unicellular alga Penium margaritaceum, showing conserved roles in cell division and wall assembly.

This paper develops CNN models to automatically classify Nugent scores from vaginal microscopy images, achieving higher accuracy than human experts.

The paper examines the expression of SARS-CoV-2-related molecules in human tissues and immune cells across health and disease states, identifying age, comorbidities, and immune cell types associated with altered expression.

The paper identifies two SNPs in SARS-CoV-2 genomes prevalent in North America, traces their origin to Europe, and suggests they could be targets for surveillance and treatment.

This study identifies TAZ as an inhibitor of GR that regulates hepatic glucose homeostasis by modulating gluconeogenic gene promoter binding.

This study shows that genetic background strain influences aortic fibrosis in hypertensive mice, with C57BL/6J mice showing more maladaptive remodeling than 129SvEv mice.