N. Zhang

This study examines age-related changes in vitellogenin vesicles and yolk organelles in C. elegans, finding significant expansion and fusion of these structures in post-reproductive worms.

This study characterizes the enhanced infectivity and antibody evasion properties of the SARS-CoV-2 Omicron subvariant BA.2.75 compared to BA.5 and other variants.

This study identifies 933 heat tolerance genes in Chlamydomonas reinhardtii through genome-wide mutant screens, showing 50% have orthologs in crops and Arabidopsis mutants are heat sensitive.

This study uses immuno-electron microscopy to map the subcellular localization of vitellogenins in C. elegans, showing they follow the classic exocytic pathway.

This study identifies Bsk830 as a tomato kinase involved in flagellin-triggered immunity, showing it regulates pre-invasion immunity and JA signaling.

The paper identifies effector recognition specificities of NbPtr1 and NbZAR1 in N. benthamiana and shows their distinct and overlapping roles in detecting bacterial effectors.

This study identifies a toxin-mediated policing system in Bacillus that punishes phenotypic cheaters, enhancing population fitness in plant rhizosphere and under stress.

This study investigates antibody evasion by SARS-CoV-2 Omicron sublineages BA.2.12.1, BA.4, and BA.5 against plasma from vaccination and BA.1 infection, showing increased neutralization escape.

This study shows that Ffar4 loss worsens cardiac inflammation and remodeling in male HFpEF-MetS mice by altering oxylipin balance.

This study introduces a new remote sensing index for urban ecological monitoring by integrating air quality data with existing ecological factors, showing improved assessment in Beijing.

This study shows that both tree species and genetic diversity increase productivity through functional diversity and trophic feedbacks, with genetic diversity effects varying between monocultures and mixtures.

The paper analyzes a segregating population of Orobanche species to investigate the genetic basis of germination specificity in parasitic plants.

This study shows that neutrophil extracellular traps (NETs) disrupt airway epithelial barrier function by causing cell death and E-cadherin degradation, which can be mitigated by alpha-1 antitrypsin.

This study shows that pancreas resident macrophages (TRMs) have distinct roles in pancreatitis and pancreatic cancer, promoting fibrosis in inflammation but driving cancer progression.

This study shows that BA.2 causes stronger antibody evasion than BA.1, particularly in SARS convalescents, and identifies key mutations responsible for this escape.

This study engineers bispecific antibodies against SARS-CoV-2, showing that one design outperforms a cocktail in neutralizing activity and breadth against variants.

This study compares the phenotypes of two Chlamydomonas reinhardtii strains, CC-1690 and CC-5325, revealing differences in growth, photosynthesis, cell wall, and circadian rhythms.

The paper identifies trafficking molecules that polarize apical membranes and PAR complexes, showing biosynthetic-secretory pathways asymmetrically expand the apical domain before PARs.

This study shows elevated ozone and nitrogen addition increase poplar rust severity by altering phyllosphere microbial communities, with clone-specific responses observed.

This study shows that homogeneous antibody-drug conjugates (ADCs) improve therapeutic efficacy in glioblastoma models compared to heterogeneous ADCs.

This study shows that the PIKA-adjuvanted SARS-CoV-2 spike protein vaccine YS-SC2-010 maintains high neutralizing activity against Omicron and other variants for up to 596 days post-vaccination in animal serum.

The paper shows that FoSir5 decrotonylates key targets to regulate metabolic state switching during conidial germination in Fusarium oxysporum.

This study shows that loss of Nrd1 function in tomato enhances resistance to Pseudomonas syringae pv. tomato by suppressing the defense gene Agp1.

The paper identifies STAT2 as a regulator of PD-L1 expression through multi-omics analysis and experimental validation, linking it to tumor immune evasion.

This study identifies increased RNA polymerase II pausing as a mechanism of acquired radiotherapy resistance in cancer cells and suggests CDK7 inhibitors as a potential therapeutic strategy.

This study identifies a novel cannibalism mechanism in Bacillus velezensis SQR9 mediated by bacillunoic acids, enhancing biofilm formation and interspecies competition through a two-component regulatory system.

This study uses hydrogen-deuterium exchange mass spectrometry to analyze Mtr4-RNA interactions, revealing substrate-dependent dynamics and interfaces in the arch domain.

This study identifies on-target point mutations caused by CRISPR-Cas9 in yeast, showing sequence dependence and involvement of NHEJ components.

The paper investigates the relationship between antagonism and phylogeny in Bacillus by analyzing biosynthetic gene clusters (BGCs) and finds a positive correlation between BGC distance and phylogenetic distance.

This study identifies shared and unique cellular responses to moderate and acute high temperatures in Chlamydomonas reinhardtii, revealing mechanisms for thermotolerance.