P. Zhang

This study develops a hydrodynamic model to explain fish orientation in channel flow, identifying a critical flow speed for successful rheotaxis through bidirectional fluid-fish interactions.

The paper uses high-speed imaging to show that dense core vesicle exocytosis occurs in two distinct modes with different kinetics and regulatory mechanisms.

This study shows AMPK and UPR interact via a positive feedback loop in muscle cells exposed to palmitate, with AMPK agonists enhancing UPR gene expression.

This study identifies HNF1B as a key mediator of prostate cancer risk through its interaction with TMPRSS2-ERG fusion, revealing germline-somatic interplay in disease progression.

This study shows that OsLEC1 inhibits photosynthesis in rice embryos to promote seed dormancy by regulating hormonal pathways and gene networks.

This study shows that reducing DAF-2 in the intestine of C. elegans nearly doubles lifespan without affecting development or reproduction.

The paper presents a chromosome-level genome assembly of Thlaspi arvense and uses it to analyze genetic variation and gene structure differences between accessions.

The paper identifies TAZ as a molecular switch driving phenotypic transition and metastasis in SCLC by analyzing mouse models and human data.

This study establishes three clinical breakpoint values for danofloxacin against Glaesserella parasuis using epidemiological, pharmacodynamic, and clinical data.

The paper classifies decidual vasculopathy into types, finding atherosis of trophoblast type is distinct and linked to lower placental weight but not specific clinical features.

The paper identifies ubiquitination of G3BP1 as a mechanism required for heat shock-induced stress granule disassembly through interaction with FAF2 and p97/VCP.

This paper identifies and characterizes a phage-derived depolymerase, Dpo71, which enhances antibiotic efficacy and immune response against multidrug-resistant Acinetobacter baumannii.

The paper investigates thylakoid membrane biogenesis in cyanobacteria by modulating light intensity, revealing the spatial-temporal dynamics of protein complex insertion and membrane organization.

The paper uses cryo-ET to analyze budding yeast meiosis and finds meiotic triple helices (MTHs) instead of expected synaptonemal complexes.

This study identifies METTL9 as a tumor-promoting methyltransferase that methylates zinc transporters, disrupting zinc homeostasis and promoting cancer growth.

This study identifies that biofilm-forming E. coli from slaughter plant equipment are more prevalent and resilient than those from cattle, suggesting that current antimicrobial interventions may inadvertently select for robust biofilm-formers.

The paper examines IFN-I autoantibodies in critical COVID-19 patients through longitudinal single-cell analysis, revealing suppressed ISG-I responses in myeloid cells.

The paper characterizes the microbiota of Chlamydomonas reinhardtii's phycosphere and finds it shares taxonomic and functional features with plant root microbiota.

The paper investigates syncytia formation between SARS-CoV-2 infected and ACE2-expressing cells, finding that it leads to pyroptosis via Caspase-9 and GSDME activation, contributing to severe COVID-19 inflammation.

This study examines genome-wide transcriptional responses of marine nematode Litoditis marina to hyposaline and hypersaline stresses, identifying conserved and specific gene expression patterns.

The paper examines how three plant metabolites affect soil bacterial communities, finding distinct impacts on taxa abundance and diversity.

This paper develops an immuno-fluorescent magnetic nanobead system for capturing, isolating, and detecting circulating tumor cells with high efficiency and viability.

This study characterizes the structure, conformation, and glycosylation of the SARS-CoV-2 spike protein expressed by the ChAdOx1 nCoV-19/AZD1222 vaccine, confirming its native-like properties.

The paper investigates host preference and invasiveness of commensal bacteria in the root microbiota of Lotus and Arabidopsis, showing host-specific adaptation and competitive advantages.

This study creates non-GMO hybrids between Saccharomyces jurei and ale yeasts to develop craft beer strains with improved fermentation and complex flavor profiles.

This study identifies ERK1/2-mediated phosphorylation of NRF1 as critical for proteasome production and stress resistance, showing therapeutic potential in cancer.

This study uses fMRI to show that amblyopia causes layer-specific changes in subcortical visual pathways, with reduced feedforward signals in the geniculostriate pathway and altered feedback signals in the retinotectal pathway.

The paper introduces IRCA to infer metabolite conversion networks from single-cell Raman spectra of isogenic populations without time-series data.

This study shows that loss of Tmem30a in podocytes causes albuminuria and glomerulosclerosis in mice, with reduced TMEM30A expression observed in human podocytopathies.