Q. Yang

This study shows that loss of TCF-1 in mature CD4 T cells reduces GVHD severity and persistence by impairing T cell function and increasing exhaustion.

This study shows TCF-7 is not needed for anti-tumor response but is required for long-term function of mature CD8 T cells.

This study identifies and characterizes two CoAT enzymes from bacteria, showing CPB6-CoAT can catalyze both butyrate and caproate synthesis, while BEY8-CoAT only catalyzes butyrate synthesis.

The paper assembles a chromosome-scale, allele-aware autotetraploid genome of alfalfa cultivar Zhongmu-4 and identifies 101 SNPs associated with 27 agronomic traits using GWAS.

The paper uses machine learning to analyze sperm morphology and collective motility in Peromyscus mice, finding that head elongation correlates with aggregation behavior.

This study shows that ssc-miR-132 reduces inflammation and apoptosis in IPEC-J2 cells caused by C. perfringens beta2 toxin by targeting DACH1.

This study shows that blocking N- and O-glycan biosynthesis reduces SARS-CoV-2 viral entry by affecting Spike protein proteolysis and RBD presentation.

This paper develops a LAMP assay for rapid detection of the nirS gene in denitrifying bacteria, showing high specificity and sensitivity compared to conventional PCR.

The paper introduces PreQual, an automated pipeline that preprocesses and quality assures diffusion weighted MRI images using multiple tools and generates QA reports.

The paper shows ATFS-1 promotes {Delta}mtDNA replication by recruiting POLG, while LONP-1 inhibition increases wildtype mtDNA binding and improves heteroplasmy ratio and OXPHOS function.

This study shows that MT1-MMP regulates tissue homeostasis via a non-proteolytic mechanism by controlling skeletal stem cell differentiation, independent of its proteolytic activity.

This paper identifies a novel allele of the chromogen gene C from wild rice that regulates anthocyanin biosynthesis differently in indica and japonica subspecies.

This paper shows that inhibiting ITK in donor T cells reduces GVHD while preserving GVT effects in allo-HSCT using murine models and a novel peptide inhibitor.

The paper investigates whether pre-existing cutaneous conditions increase SARS-CoV-2 infection risk by examining ACE2 expression and skin barrier function in human and mouse models.

This study shows UNC-45A weakens and breaks microtubule lattices independently of its effect on non-muscle myosin II, with implications for disease treatment.

The paper analyzes CpG Island gene regulation across cancers, finding that PRC2+-CGI genes show both upregulation and hypermethylation in different cancer types, indicating regulatory plasticity.

The paper identifies two SNPs in SARS-CoV-2 genomes prevalent in North America, traces their origin to Europe, and suggests they could be targets for surveillance and treatment.

This study uses a network-based simulation model to show that combining direct and indirect contact increases FMD outbreaks among beef cattle farms, while effective information-sharing networks can prevent spread and reduce economic loss.

This study investigates abortion rates and risk factors in dairy cows and sheep in Ili, China, identifying Brucella melitensis as the main pathogen and highlighting management factors contributing to reproductive issues.

This study uses an agent-based model to analyze how truck contamination and information sharing affect foot-and-mouth disease spread in U.S. cattle production systems, showing increased disease spread with indirect contact and improved resilience with information sharing.

This study shows that prenatal arsenic exposure in mice leads to transgenerational impairments in spermatogenesis, associated with epigenetic changes in Igf2 and H19.

This paper identifies a dual activity in LanD-like flavoproteins for forming aminovinyl-cysteine residues through oxidative decarboxylation and cyclization of peptides.

This study shows that maternal thrombophilia, specifically through EPCR deficiency, leads to placental abruption and severe pregnancy complications, with potential therapeutic targets in thrombin-mediated platelet activation.

This study shows that Bacillus subtilis spore enhances mucosal immunity by promoting intestinal-resident memory T cells through ICAM-1 expression on dendritic cells.

The paper analyzes non-additive effects in mixed-species litter decomposition, finding synergistic and antagonistic effects under different conditions.

The paper identifies lineage-specific activation of HNF4A in gastrointestinal adenocarcinomas through epigenomic and genomic analysis, revealing its role in promoting cancer proliferation.

The paper investigates whether Wolbachia naturally occurs in Aedes aegypti by reviewing evidence and conducting field and lab surveys, finding no confirmation of natural Wolbachia infections.

This study identifies glucose starvation and SGLT2 inhibition as synthetic lethal strategies for EGFR-WT/LKB1-mutant NSCLC, showing efficacy in xenograft models.

The paper identifies differentially expressed proteins in tumor-associated vascular endothelial cells of colorectal cancer and links some to angiogenesis and metastasis.

This study characterizes the viral community of the South Scotia Ridge using metagenomic analysis, revealing novel viral sequences and high diversity.