S. Kim

This study develops a computational framework to describe embryonic tissue dynamics, revealing a tension-fluctuation-driven rigidity transition.

This study identifies distinct B cell signatures and tertiary lymphoid structures in HPV+ and HPV- HNSCC, highlighting their role in antitumor immunity.

The paper identifies a novel activation switch loop in Plexin-B1 that enhances its GAP activity towards Rap1b through a cooperative mechanism involving conformational changes.

The paper identifies miR-24-3p as a regulator of DNA damage responses and COPD susceptibility, showing its suppression in COPD and its role in modulating apoptosis and DNA repair.

This paper shows that the ClpXP protease regulates the abundance of σAntA, an ECF σ factor controlling antimycin biosynthesis in Streptomyces.

This paper introduces DNA micro-disks with index and WORM memory features to improve DNA-based data storage reliability and accessibility.

This study generates a TBT-bp2 knockout medaka strain to investigate the function and detoxification mechanisms of tributyltin-binding proteins.

The paper identifies Linc00402 as a novel lncRNA regulating allogeneic T-cell responses through RNA-seq analysis of human T-cells post-HSCT.

This study identifies USP9X as a deubiquitylase that regulates ZNF598 stability, impacting ribosomal quality control through modulation of di-ribosome resolution.

This study shows miR-155 shifts PGE2/PGD2 balance towards an oncogenic state by regulating enzymes involved in prostaglandin synthesis.

This study screens 48 FDA-approved drugs for antiviral efficacy against SARS-CoV-2 and identifies 24 drugs with IC50 values between 0.1 M and 10 M, including niclosamide and ciclesonide.

This study identifies mitochondrial complex II disruption in intestinal epithelial cells as a key driver of T-cell mediated intestinal immunopathology across multiple disease models.

This study compares the sensitivity of primer-probe sets for detecting SARS-CoV-2 RNA in N and Orf1 genes, identifying the most sensitive sets for each.

This study identifies TM4SF5's role in modulating SIRT1 and STAT3 signaling during NAFL to NASH progression, showing age-dependent effects and potential therapeutic targets.

This study develops a computer vision method to analyze C. elegans swimming behavior and identifies genetic factors influencing exercise-induced quiescence.

This paper develops a biosensor capable of continuously measuring multiple analytes in live animals with high sensitivity and temporal resolution, demonstrating its use for glucose and insulin detection in diabetic rats.

This study examines the relationship between gut microbiota composition and monocyte recovery after hematopoietic stem cell transplantation, finding no significant association in a small cohort.

The paper benchmarks predictive models for kinase inhibitor potencies using crowdsourced data and identifies new compound-kinase interactions.

This study develops an anti-somatostatin receptor 2 antibody-drug conjugate (ADC) that effectively targets and kills neuroendocrine tumors with minimal toxicity.

This study shows that the MyD88-Syk axis drives inflammatory responses in macrophages by promoting ROS/RNS generation and phagocytic activity through Src, F-actin, and Rac1.

This study identifies METTL18 as an actin histidine methyltransferase that enhances breast cancer metastasis by promoting actin polymerization and Src activation.

This study identifies 3′-UTR shortening as a mechanism driving subtype-specific cancer growth by disrupting ceRNA networks involving housekeeping genes in breast cancer.

This study investigates how RNA could emerge from prebiotic mixtures of ribonucleotides, arabinonucleotides, and 2'-deoxyribonucleotides through nonenzymatic template-directed synthesis.

The paper identifies PSY2 as a compensatory gene for PSY1 loss in yellow pepper fruit color development.

RNF144A regulates cytokine signaling hierarchy in T cells to enhance anti-influenza immunity by promoting STAT5 activation and limiting MAPK signaling.

This study identifies two residues in Kv1.2 that act as a pH switch, showing how protonation disrupts electrostatic balance and causes channel closure through dewetting of the water cavity.

This study compares immune response kinetics between two chicken lines infected with Eimeria maxima, finding early cytokine responses in resistant chickens.

This study identifies S2Lb as a co-regulator of H3K4me3 with SDG2 in Arabidopsis, showing H3K4me3 deposition is H2Bub-independent and important for gene induction during cellular transitions.