development & morphogenesis

Genome reorganisation and expansion shape 3D genome architecture and define a distinct regulatory landscape in coleoid cephalopods

The paper investigates how genomic changes in coleoid cephalopods shape 3D genome architecture and regulatory landscapes, revealing species-specific chromatin loops and their role in neural development.

Genomic signatures of coevolving phage-bacteria interaction networks

This study investigates how coevolution between phages and bacteria affects interaction networks by analyzing genetic changes in both hosts and phages.

Lymph node contraction links sex-biased naive CD8 T cell decline to compromised antigen recognition during middle age

This study identifies sex-biased mechanisms of immune aging in males, showing lymph node contraction reduces naive CD8 T cell availability and compromises cancer antigen recognition, with potential therapeutic interventions.

RAP2.3 is required for MYB51 and SIGMA3 expression during the response of Arabidopsis thaliana to multifactorial stress combination

This study identifies RAP2.3 as essential for MYB51 and SIGMA3 expression during Arabidopsis thaliana's response to multifactorial stress combinations, revealing a regulatory pathway critical for survival under combined stress conditions.

Live-cell imaging and ultrastructure expansion microscopy reveal the dynamic intracellular life cycle of the microsporidian parasite Encephalitozoon intestinalis

3D vascular quantitation with application to computational modeling: a pre-clinical light sheet microscopy, high resolution ultrasound, nano-computed tomography comparison study

The paper compares 3D vascular imaging modalities to assess their accuracy in quantitative measurements and computational modeling of vascular morphology.

The geometry of gametic dispersal in a flying mammal, Rhinolophus hipposideros

The paper estimates natal and mating dispersal distances in Rhinolophus hipposideros, showing how mating dispersal decorrelates gene and individual flows.

Ontogeny of settlement behaviours in response to Grammatophora marina diatom biofilms in the marine polychaete, Platynereis dumerilii

This study examines age-related changes in settlement behaviors of Platynereis dumerilii larvae in response to Grammatophora marina diatom biofilms, finding increased crawling and discrimination with development.

Inter-strain diversity among coastal picocyanobacteria across salinity gradients

The paper examines how picocyanobacterial strains from different salinities adapt their growth and metabolism across varying salinity and light conditions.

Feeding a low-protein diet exacerbates the susceptibility to Citrobacter rodentium and Dextran Sulfate Sodium-induced intestinal injury in mice.

This study shows that low-protein diets increase susceptibility to intestinal injury from DSS or C. rodentium in mice, with more severe symptoms and systemic inflammation.

Conserved RGF1 peptide signaling regulates root meristem development through ROS in Arabidopsis and rice

This study shows that RGF1 peptide signaling via ROS regulates root meristem development in Arabidopsis and rice, with conserved function across dicots and monocots.

Rapid protamine evolution suppresses meiotic drive in Drosophila

A rapidly evolving essential protamine suppresses sex-chromosome meiotic drive in Drosophila.

Maternal repression of imprinted genes in endosperm by gene body demethylation

The paper shows that maternal removal of gene body methylation drives imprinting of PEGs in maize, with implications for gene regulation in rice but not Arabidopsis.

Auxin-inducible degron-mediated protein depletion in Diplonema papillatum

This study introduces an auxin-inducible degron system in Diplonema papillatum to enable conditional protein depletion and assesses its effects on key cellular processes.

Embryonic origin of cancer in newborn twins

The paper uses whole genome sequencing to study cancer spread between monozygotic twins, revealing asymmetrical embryonic lineage contributions to the placenta and twins.

Maternal ranging strategies facilitate offspring social play at energetic cost in the most solitary ape

The paper shows orangutan mothers adjust their ranging behavior to increase offspring social play, at an energetic cost.

Thioesterase modulates antibacterial Type VI secretion system via alteration in oxidative stress responses in Burkholderia

This study shows that thioesterase modulates the T6SS in Burkholderia gladioli by affecting oxidative stress responses, enhancing antibacterial activity and sensitivity to oxidative stress.

CflP couples magnesium availability to CovS signaling in Group B Streptococcus

This study identifies CflP as an accessory regulator of CovS in GBS, linking magnesium availability to virulence gene repression and immune cell cytotoxicity.

Decoupled recovery of soil physicochemistry, microbiome and methane sink function during secondary forest succession in the Eastern Himalayas

Formation of a swelling gel underlies a morphological transition in Bacillus subtilis biofilms

This study shows Bacillus subtilis biofilms use polymer composition to drive gel formation and morphological transitions through swelling and cross-linking.

Host Cellular Remodeling, Not Viral Transcriptional Inhibition, Drives Quorum Sensing Signal-Mediated Evasion of Viral Lysis in Gephyrocapsa huxleyi

The paper shows that HHQ enables Gephyrocapsa huxleyi to evade viral lysis by remodeling host processes, not by inhibiting viral transcription.

Gut Microbiota Fuel Aging Induced by Mitochondrial Dysfunction

This study shows mitochondrial dysfunction accelerates aging by disrupting gut microbiota structure and inducing immune dysregulation and inflammation through metabolic reprogramming.

Environmental control of morphological color changes in the Bigfin Reef Squid, Sepioteuthis lessoniana

This study shows that environmental conditions and age influence chromatophore density and size in squid, revealing a trade-off between number and expansion of color cells.

Distinct roles for TANGO1S domains in maintaining ER-Golgi architecture

This study investigates the functional roles of TANGO1S domains in maintaining ER-Golgi architecture by analyzing domain-deletion mutants in knockout cells.

Early rhizosphere assembly during the onset of photosynthesis reveals inoculum-constrained succession with increased phylogenetic clustering, filtering and diversity

This study tracks rhizosphere microbiome assembly in tomato plants during early development, showing inoculum-constrained succession with increased phylogenetic clustering and diversity.

Endosome motility controls light-responsive reproductive development and secondary metabolite production in Aspergillus

This study shows that endosome motility in Aspergillus species affects light-responsive development and secondary metabolite production.

Heterosis in crosses between remnant populations of the rare prairie forb Silene regia: implications for restoration genetics

This study quantifies heterosis in crosses between remnant populations of Silene regia, finding strong positive effects in two populations and varied patterns across environments.

Human spinal cord organoids recapitulate developmental and disease-associated oligodendrocyte lineage signatures

This study develops human spinal cord organoids and assembloids to model oligodendrocyte development and disease states, showing they recapitulate developmental signatures and cytokine-induced dysfunction seen in multiple sclerosis.

Mechanisms of CD4+ T tolerance to a corneal epithelial neoantigen

This study identifies inducible regulatory T cells as the mechanism for immune tolerance to corneal epithelial antigens, showing that this tolerance can be overcome by inflammatory priming.

The Longest 3D-preserved Plumage Reveals Stepwise Pennaceous Feather Evolution

The paper describes a 105 mm-long pennaceous feather from Burmese amber, showing advanced branching but incomplete tissue differentiation, suggesting asynchronous evolution of feather structures.