Sleep and Wakefulness Research

Using EEG Microstates to Examine Post-Encoding Quiet Rest and Subsequent Word-Pair Memory

The paper examines EEG microstate dynamics during post-encoding rest and finds increased microstate D and decreased microstate C, associated with memory consolidation and encoding strength.

Sleep spindles preferentially consolidate weakly encoded memories

The paper shows sleep spindles help consolidate weakly encoded memories, reducing forgetting rates compared to staying awake.

Kleine Levin syndrome is associated with birth difficulties and genetic variants in the TRANK1 gene loci.

This study identifies a genetic association between Kleine-Levin Syndrome and variants in the TRANK1 gene, with increased risk linked to birth difficulties.

A model of Ponto-Geniculo-Occipital waves supports bidirectional control of cortical plasticity across sleep-stages

The paper builds a neural mass model of PGO waves to show how sleep stages influence cortical plasticity through bidirectional synaptic changes.

Binocular disparity-based learning does not generalize to the other visual hemifield

This study investigates whether sleep enhances visual disparity discrimination and its generalization across the vertical meridian, finding no significant effect of sleep on consolidation of this perceptual skill.

A Sub-Minute Resolution Prediction of Brain Temperature Based on Sleep-Wake State in the Mouse

The paper develops a model to predict brain temperature in mice based on sleep-wake state and time-of-day, finding sleep-wake sequences explain most of the variance.

Medulla glutamatergic neurons control wake-sleep transitions

This study identifies medulla glutamatergic neurons projecting to the preoptic area that control wake-sleep transitions through chemogenetic and optogenetic manipulations.

Splitting sleep between the night and a daytime nap reduces homeostatic sleep pressure and enhances long-term memory

This study shows that splitting sleep between night and a daytime nap improves memory and reduces sleep pressure in adolescents.

Glutamatergic neurons in the preoptic hypothalamus promote wakefulness, destabilize NREM sleep, suppress REM sleep, and regulate cortical dynamics

Electrophysiological signatures of acute systemic lipopolysaccharide: potential implications for delirium science

This study examines how lipopolysaccharide (LPS) affects electrophysiological activity in mice, linking inflammation to changes in slow wave activity and potential delirium mechanisms.

Daily orexinergic modulation of the rat superficial layers of the superior colliculus - implications for intrinsic clock activities in the visual system

The paper investigates daily orexinergic modulation of the rat superior colliculus, showing circadian coordination between orexin input and visual system activity.

The chromatin remodeler ISWI acts during Drosophila development to regulate adult sleep

The paper identifies ISWI as a chromatin remodeler required for adult sleep in Drosophila, with distinct developmental roles in sleep and other behaviors.

Dynamic Auditory Remapping Across the Sleep-Wake Cycle

The paper examines how auditory neural responses change across the sleep-wake cycle, finding state- and stimulus-dependent reorganization of auditory processing.

Travelling spindles create necessary conditions for spike-timing-dependent plasticity in humans

The paper analyzes spindles in humans to show they create spatiotemporal patterns of neuronal co-firing that may support memory consolidation during NREM sleep.

Slow oscillation-spindle coupling is negatively associated with emotional memoryformation following stress

The paper examines how stress affects the relationship between slow wave sleep and emotional memory, finding that slow oscillation-spindle coupling negatively correlates with memory in stressed individuals.

Investigation of the Stress and Sleep Physiology Correlates of Next-Day Memory for Details of a Social Stressor Testing Environment

The paper investigates how stress and sleep affect memory of a social stressor environment, finding that NREM sleep physiology, not stress reactivity, is linked to memory retention in non-stressed individuals.

Correlates of Sleep and Arousal via Matrix Methods

The paper presents a matrix-based method to infer arousal state by integrating neural, metabolic, and immune system data.

Vast amounts of encoded items nullify but do not reverse the effect of sleep on declarative memory

The paper shows that sleep does not enhance forgetting of large amounts of declarative memory, contradicting the hypothesis that sleep increases forgetting at high information loads.

Stability of neocortical synapses across sleep and wake

This study investigates whether sleep and wake states drive changes in neocortical synaptic strength in juvenile rats, finding no significant changes in synaptic strength across these states.

Multiple memories can be simultaneously reactivated during sleep as effectively as a single memory

The paper shows that multiple memories can be reactivated during sleep without reducing their consolidation benefits, suggesting parallel memory processing during sleep.

Altered sleep intensity upon DBS to hypothalamic sleep-wake centers in rats

This study investigates the effects of high-frequency DBS on sleep-wake characteristics in rats, finding that it modulates sleep intensity without altering sleep proportions or stability.

Neuropeptide VF neurons promote sleep via the serotonergic raphe

The paper identifies a neural circuit in zebrafish where neuropeptide VF neurons promote sleep by activating serotonergic raphe nuclei.

CRISPR knockdown of GABAA alpha3 subunits on thalamic reticular neurons enhances deep sleep

Power and coherence in the EEG of the rat: impact of behavioral states, cortical area, lateralization and light/dark phases

The paper analyzes iEEG power and coherence in rats across behavioral states, cortical areas, and light/dark phases, finding state- and area-dependent changes and REM sleep-specific hemispheric differences.

Immunization with Mycobacterium vaccae NCTC 11659 prevents the development of PTSD- like sleep and behavioral phenotypes after sleep disruption and acute stress in mice

CREB is Required in Excitatory Neurons in the Forebrain to Sustain Wakefulness

This study shows that CREB is necessary in forebrain neurons for maintaining wakefulness but not in the locus coeruleus.

Vesicular GABA-transporter neurons in the zona incerta are maximally active during non rapid-eye movement (NREM) and rapid-eye movement (REM) sleep

The paper identifies vGAT neurons in the zona incerta that are most active during NREM and REM sleep using in vivo calcium imaging.

The laminar profile of sleep spindles in humans

This study investigates the laminar profiles of sleep spindles in humans using EEG and microelectrode recordings, finding no strong association between spindle types and laminar profiles.

Sleep is required for odor exposure to consolidate memory and remodel olfactory synapses

The paper shows that sleep is necessary for memory consolidation and synaptic remodeling in C. elegans after odor training.

The zebrafish mutant dreammist implicates sodium homeostasis in sleep regulation

The paper identifies a novel zebrafish sleep mutant, dreammist, and shows that disruption of a sodium pump regulator affects sleep duration through altered sodium homeostasis.