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Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
41 papers
Recent·Most cited
This study develops an organotypic in vitro model that recapitulates spontaneous vascular maturation processes, including vessel sprouting, smooth muscle cell recruitment, and coverage, enabling the study of vascular development and disease treatment.
bioRxiv · Aug 3, 2020 · PreprintBioengineering
R. Huang, M. Xu, H. Zhu, C. Z. Chen, E. Lee, S. He, K. Shamim, D. Bougie, W. Huang, M. Hall, D. Lo, A. Simeonov, C. Austin, X. Qiu, H. Tang, W. Zheng
This paper develops a biological activity-based modeling approach to identify novel antiviral compounds against SARS-CoV-2 with high hit rates in live virus assays.
bioRxiv · Jul 27, 2020Cell Biology
W. N. Chaudhry, E. Lee, A. Worthy, Z. Weiss, M. Grabowicz, N. Vega, B. R. Levin
The paper shows that mucoidy in E. coli allows lytic phages to persist in bacterial populations through frequent transitions between mucoid and non-mucoid states.
bioRxiv · Jun 14, 2020Microbiology
J. Kirk, J. Y. Lee, Y. Lee, C. Kang, S. Shin, E. Lee, J.-J. Song, S. Hohng
This study uses single-molecule techniques to show that yeast CHD1 remodels nucleosomes through unique DNA unwrapping and translocation dynamics involving ATP binding and hydrolysis.
bioRxiv · Feb 6, 2020 · PreprintBiophysics
W. Chaudhry, N. Vega, A. R. Govindan, R. Garcia, E. Lee, I. C. McCall, B. R. Levin
This study uses a mathematical model and experimental tests to determine the evolutionary conditions favoring lytic or temperate phage replication modes in bacterial populations.
bioRxiv · Oct 30, 2019 · PreprintEvolutionary Biology
E. Lee, B. Vila Nova Santana, E. Samuels, F. Benitez Fuente, E. Corsi, M. A. Botella, J. Perez Sancho, S. Vanneste, J. Friml, A. Macho, A. Alves Azevedo, A. Rosado
The paper identifies a Ca2+-sensitive complex at ER-PM contact sites that relocalizes in response to REE-induced endocytosis, influencing cytosolic Ca2+ signaling and ER-PM communication during stress.
bioRxiv · Jul 31, 2019Plant Biology
J. L. Martinez, F. Arnoldi, E. M. Schraner, C. Eichwald, D. Silva-Ayala, E. Lee, E. Sztul, O. R. Burrone, S. Lopez, C. F. Arias
This study shows that GBF1 is required for rotavirus replication by facilitating VP7 and NSP4 processing and virion assembly.
bioRxiv · Apr 29, 2019Microbiology
L. Huang, P. Deighan, J. Jin, Y. Li, E. Lee, S. S. Mo, H. Hoover, S. Abubucker, N. Finkel, L. McReynolds, A. Hochschild, J. Lieberman
The paper uses p19 to capture RNase III-cleaved dsRNA in E. coli, revealing widespread antisense transcription and its potential role in stress responses.
bioRxiv · Jan 4, 2019Microbiology
I. Shats, J. Liu, J. G. Williams, L. J. Deterding, C. Lim, E. Lee, W. Fan, M. Sokolsky, A. V. Kabanov, J. Locasale, X. Li
This paper shows bacteria enhance mammalian NAD metabolism by using a deamidated biosynthesis pathway, contributing to drug resistance and improving NAD-boosting efficiency.
bioRxiv · Dec 7, 2018Biochemistry
C. L. Sawyers, E. Lee, J. Wongvipat, D. Choi, P. Wang, D. Zheng, P. A. Watson, A. Gopalan
This study identifies GREB1 as a driver of antiandrogen resistance in prostate cancer by amplifying androgen receptor output through enhanced DNA binding and p300 recruitment.
bioRxiv · Oct 2, 2018Cancer Biology
G. Kim, M. Lee, S. Youn, E. Lee, D. Kwon, J. Shin, S. Lee, Y. S. Lee, Y. Park
This study measures 3D refractive index and membrane properties of live erythrocytes from Pelophylax nigromaculatus to compare interspecific differences with mammals.
bioRxiv · Oct 20, 2017Biophysics