J. Park

The paper shows that Prochlorococcus in iron-depleted regions uses siderophores for iron uptake, with this trait more common in the North Pacific than the North Atlantic.

This study identifies HSBP as a repressor of HEI10 transcription and meiotic crossovers in Arabidopsis by binding to HSFs and maintaining DNA methylation at the HEI10 promoter.

The paper introduces a multi-camera array microscope (MCAM) that enables high-resolution, multi-scale imaging of behavior and neural activity in model organisms.

The paper proposes a deep learning algorithm for detecting hollow heart in potato tubers using consumer-grade hardware, achieving improved classification performance compared to human scoring and X-ray methods.

This study shows an inactivated multivalent influenza A vaccine provides broad protection against diverse IAV subtypes in mice and ferrets, including non-vaccine strains, suggesting its potential as a universal vaccine.

This study identifies spartin as a receptor mediating selective autophagy of lipid droplets and links its dysfunction to Troyer syndrome.

This study shows that capicua (CIC) regulates thymic T cell development by controlling positive and negative selection and TCR signaling, preventing autoimmunity.

This paper develops a framework for rapid bacterial species identification using 3D quantitative phase imaging and artificial neural networks, achieving 99.9% accuracy with single colony-forming units.

The paper analyzes immune cell diversity across 15 human tissues using single-cell RNA sequencing and VDJ sequencing, revealing tissue-specific features and clonal architecture of T and B cells.

The paper examines how tumor mutation burden affects antigen presentation pathway genes and finds that APG mutations are linked to improved progression-free survival with PD-1 inhibitors.

This study tests virtual prism adaptation therapy using a depth-sensing camera and fNIRS in healthy adults to assess behavioral and cortical changes during adaptation phases.

The paper links Florida milk production to phosphate levels in Lake Okeechobee over 47 years, suggesting phosphorus may have driven a recent decline in water column loading.

This study identifies systemic tissue and cellular disruption from SARS-CoV-2 infection using autopsy and spatial omics data, showing tissue-specific damage and transcriptional changes.

The paper shows red blood cells detect and bind DNA, triggering immune responses during infections.

This paper presents a computationally designed dual-ring biobot that demonstrates robust forward motion and rotational steering through differential electrical stimulation.

This study identifies P4HA2-dependent prolyl hydroxylation of YAP1 as a suppressor of prostate cancer cell migration, invasion, and metastasis.

The paper shows IL-33 enhances ILC-mediated resistance to Toxoplasma gondii by promoting IFN-γ production and reducing parasite replication.

This study shows that PD-L1-PD-1 interactions regulate Treg cell populations at homeostasis and during infection, limiting their numbers to enhance pathogen-specific CD4+ T cell responses.

This study identifies four subtypes of castration-resistant prostate cancer using ATAC-seq and RNA-seq data, revealing novel therapeutic targets and classification for 370 patients.

This paper introduces metrics to group pathology cohorts for deep learning cancer diagnosis, balancing model count and performance without linearly increasing models with cohort numbers.

This paper introduces MOAlmanac, a clinical interpretation algorithm that integrates genomic and transcriptional data to improve precision cancer treatment decisions by considering second-order molecular features.

The paper identifies proximal tubule cell state and metabolism as coupled by nuclear receptors in kidney disease using single-cell RNA-sequencing.

This study shows lopinavir and ritonavir do not inhibit SARS-CoV-2 main protease activity in vitro, suggesting they may not be effective for COVID-19 treatment.

The paper designs genetically-encoded biosensors to measure SWEET transporter activity in plants and develops a mathematical model to explain their response.

A single dose of the STARR-based SARS-CoV-2 vaccine LUNAR-COV19 induces protective adaptive immunity in mice, including strong antibody and CD8+ T cell responses, and full protection against viral challenge.

This study identifies redundant mechanisms by which Candida albicans spreads in zebrafish, using immune cells or blood flow.

This study designs and characterizes prefusion-stabilized SARS-CoV-2 spike variants to improve protein yield and stability for vaccine and diagnostic development.

This study characterizes the molecular features and immune profile of sarcomatoid and rhabdoid renal cell carcinoma, showing their responsiveness to immune checkpoint inhibitors and identifying key genetic and transcriptional determinants.

This study identifies SDE2's role in stabilizing the TIMELESS-TIPIN complex to protect stalled replication forks and maintain genomic integrity.