Khaled A. Khairy

BRD4 recruitment desilences transcription without erasure or depletion of repressive chromatin

This study shows that BRD4 recruitment can desilence transcription within repressive chromatin without removing H3K9me3 or HP1, challenging conventional models of chromatin regulation.

Suppression of non-canonical autophagy induces endothelial and cardiac dysfunction

This study shows that disrupting non-canonical autophagy (LANDO) impairs endothelial and cardiac function by disrupting VEGFR2 recycling and Hb- expression.

Canonical Hedgehog Signaling Controls Astral Microtubules and Mitotic Spindle Orientation in Neural Progenitors and iPSCs

This study shows that Hedgehog signaling regulates mitotic spindle orientation in neural progenitors and iPSCs by affecting astral microtubules and transcriptional regulation of microtubule dynamics.

A Scalable and Modular Automated Pipeline for Stitching of Large Electron Microscopy Datasets

The paper presents a scalable pipeline for assembling large electron microscopy datasets into 3D volumes, achieving high throughput and modular design for efficient processing.

A Connectome and Analysis of the Adult Drosophila Central Brain

The paper presents a detailed connectome of the adult Drosophila central brain, including new methods for data analysis and biological insights into neural circuit organization.

A Connectome of the Adult Drosophila Central Brain

A dense electron-microscopy reconstruction of half the fly central brain, with nearly every cell typed and queryable online, turns months of tracing partners into a database lookup.

A Complete Electron Microscopy Volume Of The Brain Of Adult Drosophila melanogaster

The paper provides a complete electron microscopy volume of the adult Drosophila melanogaster brain, revealing new insights into synaptic connectivity and neuronal circuitry.