Neurotransmitter Receptor Influence on Behavior

The paper identifies genetic loci and pathways associated with cocaine self-administration in mice using GWAS and TWAS, highlighting Trpv2 as a key gene.

This study investigates the role of dopamine in motor vigor, showing that it acts permissively rather than directly specifying movement speed and amplitude.

This study shows that biological sex moderates how personality traits like anxiety and sign-tracking affect remifentanil self-administration in rats.

The paper compares microdialysis and fiber photometry for measuring dopamine in awake mice after amphetamine exposure, finding good correlation between the two methods.

This study compares dopamine synthesis and cognitive flexibility between hormonal contraceptive users and non-users using PET imaging and behavioral assessments.

This study shows chronic restraint stress reduces resistance to punishment during cocaine self-administration in male rats, an effect mediated by dopamine D1-like receptors in the prelimbic cortex.

The paper withdraws its manuscript as its contents have been merged into another preprint.

This study uses a novel pH-sensitive reporter to show cocaine induces transient DAT internalization and prolonged membrane reinsertion in axons.

This study investigates the role of tonically active neurons (TANs) in primate striatum, finding that their activity reflects interactions between time processing and reward prediction.

The paper investigates sex-specific neural encoding of threat and non-threat cues in nucleus accumbens afferents of male and female mice, revealing differences in behavior suppression.

This study shows chronic corticosterone impairs reward-seeking in both sexes by sex-specific effects on dopamine content and transporter function in the dorsomedial striatum.

This study examines how adding nicotine to cocaine self-administration in rats affects behavior under different reinforcement schedules, finding reduced responding under long access but increased responding under progressive ratio conditions.

The paper shows that locus coeruleus norepinephrine enhances visual attention by selectively improving sensory discrimination in non-human primates without affecting motor processing.

The paper identifies common brain regions activated by both physiologically and socially needed stimuli and links them to serotonin receptor distribution.

This study investigates dopamine's role in human reinforcement learning using pharmacological interventions and fMRI, finding reduced decision thresholds under dopaminergic manipulations.

This study shows that compulsive coping behaviors in rats develop through dopamine-dependent mechanisms in the dorsolateral striatum after prolonged adjunctive drinking.

The paper identifies how specific neurons in the medial accumbens shell encode reward preference and show distinct roles in driving reward behavior.

This study shows that activating mGlu2/3 receptors in the dorsal striatum reduces cocaine-seeking behavior in rats after intermittent cocaine use.

This study investigates the rapid effects of dopaminergic modulation on striatal spiking activity and finds that physiological DA levels do not strongly influence spiking, except when DA exceeds reward-matched levels.

The paper investigates how restoring D2-to-D1-neuron functional correspondence in aged mice enhances goal-directed action by manipulating striatal neurons.

The paper identifies a correlation between low Arc mRNA levels in specific locus coeruleus neurons and the development of compulsive polydipsic drinking in rats.

This study examines how long-term methamphetamine self-administration affects glutathione levels, mitochondrial respiration, and dopamine neuron activity in mice.

This study investigates how D3 receptor antagonists modulate Akt/mTOR and ERK1/2 pathways in response to different stressors during cocaine relapse.

The paper investigates how dopamine and acetylcholine interact in the striatum during decision making, revealing their dynamic relationship and the role of local and long-range inputs.

The paper shows that dopamine and acetylcholine levels in the striatum of mice fluctuate spontaneously with the same temporal relationship as during reward, driven by glutamatergic afferents rather than direct interactions between the neuromodulators.

This study shows that postpartum estrogen withdrawal in mice increases anxiety-like behavior and ΔFosB expression in nucleus accumbens D1 and D2 neurons.

The paper identifies cell type-specific gene regulatory changes in the amygdala of rats with varying cocaine addiction-like behaviors, linking them to energy metabolism, GABAergic inhibition, and chromatin accessibility.

This study shows NPAS4 regulates drug-cue associations and relapse-like behavior by controlling the activation balance between D1- and D2-MSNs in the nucleus accumbens.

The paper identifies a slow serotonergic recurrent inhibitory network in the dorsal raphe nucleus that generates non-linear dynamics and winner-take-all computations, affecting reward-conditioned behavior.