Advanced Neuroimaging Techniques and Applications

Investigating the sensitivity of the diffusion MRI signal to magnetization transfer and permeability via Monte-Carlo simulations

This study uses Monte-Carlo simulations to show that permeability and magnetization transfer significantly affect diffusion MRI signal and parameter estimation in cylindrical substrates.

Connectome-based spatial statistics enabling large-scale population analyses of human connectome across cohorts

This paper introduces CBSS, a framework for analyzing structural connectomes across multiple cohorts, showing its reliability and utility in cross-cohort diffusion MRI studies.

Assessing the Influence of Tractography Methods on Detected White Matter Microstructure in Alzheimer's disease

The paper compares deterministic and probabilistic tractography methods in ADNI data, finding bundle-level differences in white matter microstructure metrics between the two approaches.

Deep-Learning Cortical Registration Guided by Structural and Diffusion MRI and Connectivity

This paper introduces a deep-learning method that improves cortical registration by integrating structural and diffusion MRI data with connectivity features, showing better functional alignment than FreeSurfer.

Evaluating Sample-Size Efficiency and Sensitivity of Tractometry in Alzheimer's Disease

This study evaluates how sample size and resolution affect tractometry's sensitivity and specificity in detecting dementia and amyloid-related effects in Alzheimer's disease.

Hierarchical X-ray microscopy and mesoscopic diffusion MRI in the same brain reveal the human connectome across scales

The paper presents a multimodal imaging pipeline that combines diffusion MRI and high-resolution X-ray microscopy to map the human connectome across multiple scales.

Bridging the microstructural gap in human connectomics using hierarchical phase-contrast tomography as a reference for diffusion MRI in the human brain

This paper uses HiP-CT to image microstructural fiber orientations in the human brain, showing greater complexity than dMRI while being non-destructive.

Modeling a Shared Reality of Tractography through Varied Structural Imaging

This paper introduces a method to generate white matter tractograms from FLAIR images without diffusion data, showing it captures structural probabilities similar to diffusion-based tractography.

A human subcortical connectome at 400 μm resolution

This paper presents the first extensive reconstruction of human subcortical fiber pathways using ultra-high-resolution dMRI, providing a high-definition atlas with clinical applications.

Analysis of cortical dysplasias using b-tensor encoding diffusion MRI in an animal model

This study uses b-tensor encoding diffusion MRI in a murine model to assess microarchitectural changes in cortical dysplasias, finding reduced fractional anisotropy and dysorganized myelinated fibers in treated animals.

Heterogeneity of white matter structure in the human brain

The paper characterizes the 3D organization of large axons in human white matter, revealing distinct architectural patterns across different brain regions.

Encoder-based Curvature-Aware Regularization for estimating asymmetric fiber orientation distribution functions in diffusion MRI

This paper introduces EnCAR, a method for estimating asymmetric fiber orientation distribution functions in diffusion MRI, showing improved performance in complex regions.

Analytic Bounds on GAMLSS Model Variability of Normative White Matter Brain Charts

The paper evaluates the variability of GAMLSS-based brain charts using analytic and empirical methods, finding low coefficient of variation across most white matter features.

Bridging Histology and Tractography: First In-Vivo Visualization of Short-Range Prefrontal Connections Informed by Primate Tract-Tracing

This study maps short-range prefrontal connections in the human brain using tractography informed by primate histology, achieving high precision and accuracy.

Multidimensional MRI reveals cellular-scale microstructural phenotypes in human brain aging

This study uses multidimensional MRI to analyze cellular-scale microstructural changes in the human brain across aging, revealing increased heterogeneity and loss of microscopic restriction.

Along-Tract Microstructural Alterations Associated with Stimulant Misuse Localized using Diffusion MRI Tractometry

This study uses diffusion MRI tractometry to identify localized white matter microstructural changes associated with stimulant misuse, finding distinct patterns for amphetamine use compared to cocaine use.

Surface-based Tractography uncovers 'What' and 'Where' Pathways in Prefrontal Cortex

The paper uses tractography to show that FEF connects to dorsal visual streams and IFJ to ventral visual streams, supporting their roles in spatial and non-spatial processing.

The role of white matter myelin in structural-functional network coupling

This study integrates multi-feature white matter connectivity into structure-function brain models, showing that myelin strongly predicts functional connectivity across brain regions and timescales.

Multi-dimensional diffusion MRI at ultra-high gradient strength for mapping axonal architecture and microstructure in the primate brain

This paper presents high-resolution diffusion MRI data from macaque and human brains, enabling detailed mapping of axonal architecture and microstructure.

Frequency-dependent diffusion tensor distribution imaging in the evaluation of ischemic stroke

This study introduces frequency-dependent diffusion tensor distribution imaging (ωDTD) combined with machine learning to better characterize ischemic tissue damage in rats, showing improved representation of microstructural changes compared to conventional DTI.

Spatiotemporal Variation in White-Matter Development Across Early Childhood

This study examines spatiotemporal patterns of white matter development in children using longitudinal diffusion imaging data, revealing distinct developmental axes within tracts.

Individuals born with congenital cataracts exhibit both persisting impairment and considerable recovery of white matter microstructure after sight restoration

This study examines white matter microstructure changes in individuals with congenital cataracts after sight restoration, finding both persistent impairment and significant recovery compared to controls.

Characterising the diffusion functional signature of negative BOLD with interleaved TMS-fMRI in the human brain

The paper investigates negative BOLD responses using interleaved TMS-fMRI and dfMRI in the human brain, finding no ADC-fMRI response and suggesting sensitivity to subtle neural activity in ipsilateral regions.

The effect of microstructural variations in tendon and ligament on diffusion tensor MRI

This study investigates how microstructural variations in tendon and ligament affect diffusion tensor MRI metrics through simulations of fiber networks.

Data-driven classification of tissue water populations by massively multidimensional diffusion-relaxation correlation MRI

This paper uses unsupervised clustering on diffusion-relaxation MRI data to classify tissue water populations in rat and human brains, revealing more complex tissue structures than traditional methods.

Dynamic structural connectivity changes in cortical and cortico-striatal strokes in mice

This study compares structural connectivity changes in two stroke models in mice, finding that lesion size and location affect dynamic connectivity patterns in sensorimotor regions.

Modelling motion-induced signal corruption in steady-state diffusion MRI

This paper models and corrects motion-induced signal corruption in DW-SSFP diffusion MRI using an extended phase graph framework and provides open-source software for future studies.

Gene dosage effects of 22q11.2 copy number variants on in-vivo measures of white matter axonal density and dispersion

Age-related cerebello-thalamo-cortical white matter degradation and executive function performance across the lifespan

This study examines age-related changes in cerebello-thalamo-cortical white matter and their association with executive function performance across adulthood.

Reproducibility and reliability of Free-Water-corrected Diffusion Tensor Imaging of the brain: Revisited

This study evaluates the reproducibility and reliability of free-water-corrected diffusion tensor imaging (DTI) in healthy human brain white matter across different acquisition settings and correction methods.