L. Yu

The paper shows that disordered spring climate disrupts migration and breeding of a short-distance fish, leading to population decline and larval flux reduction.

This study demonstrates that iDPC-STEM provides superior contrast and structural detail in biological samples compared to conventional TEM, especially at low doses and for thick sections.

The paper shows that loss of KMT5B in DIPG cells depletes retained H3K27me3 loci, leading to transcriptional changes that promote tumorigenesis.

The paper uses a land surface model and foliar nitrogen isotope data to assess global nitrogen limitation, finding that leaf δ15N trends cannot alone determine nitrogen limitation and that model integration reveals underlying drivers.

The paper uses RNA-seq to show that GmSALT3 improves ROS detoxification in salt-stressed soybean roots by enhancing antioxidant activity and related pathways.

The paper identifies CSA1 as a TIR-NBS-LRR protein required for autoimmune cell death in Arabidopsis when BAK1 and BIR3 are mutated, linking BAK1 to NLR proteins in immune responses.

This study identifies OsNLP3 as a key regulator of nitrogen use efficiency and grain yield in rice under nitrate-sufficient conditions.

The paper identifies two distinct GUX clades in softwood that produce different glucuronic acid patterns on xylan, affecting biomass recalcitrance.

This study validates stable GPCR:Gs complexes without Nb35 stabilizers and evaluates 200kV vs 300kV cryo-EM imaging for drug discovery.

This paper demonstrates that polymer bilayers are stable and leak-free at high guanidinium chloride concentrations, enabling reliable protein channel recordings.

This study characterizes the dynamic changes in B-cell receptor repertoires of COVID-19 patients using next-generation sequencing, revealing clonotype overlap, lineage expansion, and V gene usage patterns.

Heated Ni-foam filters effectively catch and kill airborne SARS-CoV-2 and Bacillus anthracis spores.

The paper identifies cross-reactivity of a commercial NCAPH2 antibody with SWI/SNF complex components, affecting immunoprecipitation experiments.

This paper demonstrates achieving atomic resolution cryo-EM structures for membrane proteins and apo-ferritin using advanced hardware, enabling detailed structural analysis and hydrogen bonding visualization.

The paper identifies a novel copper-sensing two-component system, DsbRS, in Pseudomonas aeruginosa that activates the dsbDEG operon involved in copper resistance.

The paper shows that the interaction between UTX and DNMT1 regulates diet-induced myogenic remodeling in brown fat by maintaining brown adipocyte identity and thermogenic function.

This study shows an inactivated SARS-CoV-2 vaccine induces neutralizing antibodies and CTL responses in rhesus macaques, effectively preventing viral replication and lung inflammation.

The paper identifies that HPV oncogenes are expressed from a single integration site in cervical cancer cell lines, revealing mechanisms of viral-host fusion transcript production and their impact on cell growth.

This study assesses the effectiveness of riverine water eDNA for monitoring aquatic and riparian biodiversity, finding it effective for detecting species and bioinformation in specific conditions.

This study shows that extracellular vesicles from thy1-positive spermatogonia suppress the proliferation of spermatogonial stem cells in vitro without inducing apoptosis.

This study evaluates givinostat's efficacy in treating NASH by reducing inflammation and fibrosis in mouse models.

This study identifies NTF3 as a fat-derived neurotrophic factor that regulates sympathetic innervation and thermogenesis in adipose tissue, influencing energy metabolism and obesity.

This paper shows that the FDA-approved drug Nelfinavir inhibits lytic cell-free transmission of certain human adenoviruses but not non-lytic transmission.

This study examines the impact of thrombotic microangiopathy (TMA) on renal outcomes in Brazilian IgA nephropathy patients, finding that TMA is associated with worse clinical outcomes and progression to chronic kidney disease.

The paper introduces EER data format for cryoEM DDD movies, preserving spatial and temporal resolution without increasing file size.

The paper uses a two-step molecular approach to delimit species in the spider genus Heptathela, identifying 20 putative species from 180 sampled individuals.

The paper introduces PALP, an imaging method that detects and quantifies polyunsaturated phospholipids by inducing peroxidation with laser pulses, enabling non-invasive monitoring of lipid unsaturation and ferroptosis in live cells.

This study shows that POMK phosphorylates core M3 to enable LARGE to elongate matriglycan on dystroglycan, preventing muscular dystrophy.

This study simulates mosquito behavior in response to spatial repellents and insecticide resistance using a modified self-propelled particle model, finding that resistant mosquitoes may be less affected by repellents.