Q. Liu

This study shows that Smad4 loss promotes lung cancer metastasis by upregulating PAK3 through miRNA regulation, suggesting Smad4 LOF as a prognostic marker and therapeutic target.

This study identifies ZmHXK7 as a maize hexokinase gene that improves salt tolerance in transgenic Arabidopsis by enhancing seedling growth and reducing stress inhibition.

This study identifies EXOSC1 as an endogenous source of mutation in KIRC that promotes DNA damage and sensitizes cells to PARP inhibitors.

This study shows that the Hippo pathway regulates density-dependent proliferation of iPSC-derived cardiac myocytes by modulating YAP/TAZ activity, with small molecules enhancing proliferation in low-density conditions.

This study identifies S6K2 as a vulnerability in MAPK inhibitor-resistant NRAS-mutant melanoma, showing its abrogation disrupts lipid homeostasis and triggers cell death.

This study identifies DDX21 cleavage by caspase-3/6 during virus infection as a mechanism to suppress IFN-β signaling by disrupting the DDX1-DDX21-DHX36 complex.

The paper uses multi-scale predictive modeling to identify ibudilast as a potential therapeutic for Alzheimer's disease by improving cognition and reducing pathology in a transgenic rat model.

This study shows that two rice pests, the brown planthopper and the rice striped stem borer, cooperate by jointly attacking rice plants, improving plant quality and reducing parasitism risk.

This study develops and evaluates two multi-epitope vaccines against H. pylori using computer-aided design, showing they reduce bacterial colonization and stomach damage in infected mice.

The paper determines the structure of the SARS-CoV-2 E protein-PALS1 complex using cryo-EM, revealing a hydrophobic interaction that explains viral spread and suggesting therapeutic targets.

This study shows that SARS-CoV-2 N protein modulates innate immunity by both suppressing and promoting IFN-I and inflammatory responses depending on its dosage.

This study develops a multi-epitope chimeric antigen (MECU) that generates a broadly reactive antibody response against H. pylori and reduces stomach colonization in mice.

The paper identifies and evaluates strong constitutive promoters in Listeria monocytogenes to enhance foreign antigen expression, finding P18 as the most effective.

This study identifies CTPS1 as a target for antiviral therapy by showing it suppresses interferon induction and promotes viral replication in SARS-CoV-2 infection.

This study develops an OMV-based vaccine using Salmonella Typhimurium to deliver Shigella flexneri 2a O-polysaccharide antigen, showing protection against lethal pulmonary infection in mice.

This study shows that inhaled anesthetics reduce neural excitability by disrupting multiple-water entanglement networks, which amplify hydroxide ion concentration changes.

This study identifies a novel folliculogenesis and follicular placentation mechanism in black rockfish, highlighting hormonal changes and conserved genes in placental development.

This study identifies FDA-approved drugs that inhibit urease activity in H. pylori, offering potential new treatments for infections.

This study links phospholipid and lysophospholipid levels to faster HIV rebound after treatment interruption, suggesting their role in viral persistence and inflammation.

This paper develops data-informed strategies to design hydrolytic nanozymes with enhanced catalytic activity and broad substrate specificity.

This study identifies VAP-A as a key regulator of RNA-containing extracellular vesicle biogenesis and shows its role in miR-100 transfer and tumor formation.

This study uses graph theory to analyze how intranasal oxytocin affects frontal brain network properties and links these changes to personality traits.

The paper investigates the mechanical anisotropy of ZIKV xrRNA1 using single-molecule nanopore sensing and molecular dynamics simulations, revealing its dependence on Mg2+ and tertiary interactions.

This study identifies a new orthonairovirus, SGLV, associated with human febrile illness in northeastern China, showing its presence in ticks and clinical symptoms in infected patients.

This study shows that influenza A virus pre-infection increases SARS-CoV-2 infectivity in multiple cell types and worsens lung damage in mice.

This study shows heat stress inhibits meiotic recombination in Arabidopsis by reducing DSB formation and homolog synapsis, affecting chromosome axis stability and recombinase levels.

This study identifies spermidine and spermine as natural substrates of the Acinetobacter baumannii AmvA efflux pump, revealing its role in polyamine transport and antibiotic resistance.

This study identifies CVB3 VP1 as an inhibitor of cell proliferation by disrupting MAT1 interaction with the CAK complex, thereby blocking CAK-CDK4/6-Rb signaling in pancreatic cells.

This study shows that dyclonine inhibits TRPV3 channels in keratinocytes, rescuing cell death and reducing pruritus in a mouse model.

The paper shows that many bat species cannot host SARS-CoV or SARS-CoV-2 due to ACE2 receptor incompatibility, with genetic analysis identifying restrictions to viral entry.