Y. Wang

The paper shows that the ratio of toxic to nontoxic miRNAs in RISC predicts platinum sensitivity in ovarian cancer.

The paper shows that using human airway cells prevents SARS-CoV-2 from mutating its multibasic cleavage site during propagation.

This study reports cryo-EM structures of CALHM1 channels and proposes a mechanism for ATP permeation through dynamic N-helix movement.

This study identifies the ZmCd1 gene controlling cadmium accumulation in maize grains and develops molecular markers for breeding low-Cd maize varieties.

The paper identifies two RNA fragments that can synthesize a 9-mer poly-lysine in Mg2+ solution, suggesting a mechanism for protein-free peptide ligase.

This paper introduces a novel EGFR-TKI, CM93, which shows improved brain penetration and efficacy against EGFR-mutated glioblastoma in vitro and in vivo.

This paper demonstrates that iRGD-liposomes enhance the delivery and efficacy of AR-ASO in treating prostate cancer and bone metastasis without increasing toxicity.

This study uses visible-light OCT to analyze IPL sublayers in glaucoma and healthy subjects, finding that middle sublayer thinning is most significant in glaucoma.

This study examines SFD patient-derived iPSC-RPE for extracellular matrix dysfunction and oxidative stress, finding increased sub-RPE deposits and elevated 4-hydroxyproline levels.

The paper identifies how Met30 senses sulfur status through hydrogen sulfide to regulate Met4 ubiquitination and control sulfur amino acid metabolism in yeast.

This study determines the crystal structure of pDLA-88*001:01 and identifies its peptide-binding motif, revealing structural differences between two categories of DLA-88 alleles in dogs and their implications for antiviral immunity.

This study characterizes and corrects noise non-uniformity in back-illuminated sCMOS cameras, showing that corrections can improve image quality for microscopy applications.

This study compares the immunogenicity of mRNA-LNP vaccines to protein vaccines in nonhuman primates, finding comparable or superior HIV-1 antibody responses.

This study shows that helical pitch size determines microtubule plus end dynamic instability through stochastic simulations, finding that 1.5 dimer pitch optimizes growth and shrinkage phases.

This paper develops an ultrasensitive biosensor to quantify SARS-CoV-2 RBD and ACE2 interactions in cells and in vitro, enabling rapid evaluation of viral mutants and drug candidates.

This study uses fMRI to show that amblyopia causes layer-specific changes in subcortical visual pathways, with reduced feedforward signals in the geniculostriate pathway and altered feedback signals in the retinotectal pathway.

This study investigates the toxic effects of 1,4-dioxane in mice using histopathology and multi-omics approaches, finding DNA damage counterbalanced by repair mechanisms with no systemic metabolic impact.

This paper introduces an automated algorithm to improve AI-augmented molecular dynamics by maximizing time-scale separation, tested on three benchmark problems.

This paper develops a microengineered lung organ chip model to study SARS-CoV-2-induced lung injury and immune responses, revealing distinct cellular responses and the role of immune cells in inflammation.

This study identifies a brain-muscle signaling axis activated by infections and chronic diseases that reduces muscle performance through cytokine-dependent mechanisms.

This study presents the first de novo genome of Jasminum sambac and identifies gene clusters and pathways involved in flower fragrance biosynthesis.

This study shows that DSS-induced colitis in mice damages colonic crypts, leading to reduced smooth muscle tension and impaired myogenic contractions.

The paper develops a novel isothermal amplification method (LMCP) for detecting Oryza sativa ITS with higher sensitivity and speed compared to LAMP.

This study isolates and identifies phosphate-solubilizing bacteria from soybean rhizosphere soil, finding strains that promote plant growth through organic acid secretion and indole acetic acid production.

The paper analyzes ARG hosts in WWTPs using metatranscriptomics, finding 45% of genomes express multi-antibiotic resistance genes, with pathogens and denitrifying bacteria as key hosts.

This study identifies ImuA's role in Myxococcus xanthus by showing it interacts with RecA1 and ImuB, inhibits RecA1 activity, and participates in both TLS and template switching pathways.

The paper identifies four linear B-cell epitopes on the SARS-CoV-2 spike protein that can elicit neutralizing antibodies in multiple species.

This study identifies rosmarinic acid as a potent inhibitor of amylin aggregation and shows its efficacy in reducing amyloid deposits and mitigating diabetic pathology in HIP rats.

This paper develops a BSL-2 cell culture system for producing SARS-CoV-2 virus-like particles to enable safe antiviral screening and life cycle studies.

This study develops a high-throughput single-cell DNA library preparation method for CNV detection and applies it to identify clonal evolution in hepatocellular carcinoma recurrence.