Sleep and Wakefulness Research

Delta-rhythmic activity in the medulla develops coincident with cortical delta in sleeping infant rats

The paper investigates the development of delta-rhythmic activity in the medulla of sleeping infant rats and finds it coincides with cortical delta emergence, suggesting a role for medullary structures in regulating sleep.

Regulation of stress-induced sleep fragmentation by preoptic glutamatergic neurons

This study identifies POA glutamatergic neurons as regulators of stress-induced sleep fragmentation through optogenetic manipulation and calcium activity analysis in mice.

Modulating social learning-induced evaluation updating during human sleep

The paper investigates whether sleep can modulate social learning-induced evaluation changes by reactivating memories during sleep, finding that cue-elicited EEG activity predicts enhanced evaluation updates.

Maturation-dependent changes in cortical and thalamic activity during slow waves of light sleep: insights from a combined EEG-fMRI study

This study uses EEG-fMRI to examine age-related changes in cortical and thalamic activity during slow waves in children, showing posterior-to-anterior shifts and thalamic maturation.

Adenosine Kinase regulates Sleep Timing and the Homeostatic Sleep Response through Distinct Molecular Pathways

This study investigates how Adenosine Kinase affects sleep timing and homeostatic sleep response through distinct molecular pathways in mice.

Sleep loss impairs myelin function by altering cholesterol metabolism in oligodendroglia

This study shows sleep loss impairs myelin function by disrupting cholesterol metabolism in oligodendrocytes, leading to conduction delays and motor deficits.

Phase-amplitude coupling of NREM sleep oscillations is unaffected by pre-sleep learning but related to overnight memory gains depending on the declarative learning paradigm

This study finds that phase-amplitude coupling between spindles and slow oscillations during NREM sleep is stable and not affected by pre-sleep learning, but correlates with memory consolidation in a specific learning paradigm.

Synaptic strength dynamics at cortical pathways is encoded by vigilance states duration

The paper shows that synaptic strength at hippocampal pathways correlates with vigilance state durations, suggesting sleep architecture influences memory through synaptic modulation.

Post-training sleep modulates motor adaptation and task-related beta oscillations.

This study shows that sleep after motor adaptation training improves performance and alters beta oscillations and EEG spectral slope, with sleep spindles predicting success.

Non-REM parasomnia experiences share EEG correlates with dreams

The paper investigates EEG correlates of parasomnia experiences and finds similarities with dream-related neural activity.

Spatial transcriptomics reveals unique gene expression changes in different brain regions after sleep deprivation

This study uses spatial transcriptomics to show that sleep deprivation causes region-specific gene expression changes in the brain, with the hippocampus showing the most significant alterations.

Sleep-state dependent cerebellar processing in adult mice

This study investigates how sleep affects cerebellar processing in adult mice by examining correlations between muscle twitches, EEG, and climbing fiber activity during different sleep stages.

Medial temporal lobe functional network architecture supports sleep-related emotional memory processing in older adults

This study examines how network integration and centrality in the medial temporal lobe during NREM sleep relate to emotional memory retention in older adults.

Thalamocortical Spindles occur during Rapid Eye Movement Sleep in Mouse Somatosensory Pathway

The paper identifies two substates of REM sleep in mice, showing alternating high and low activation states in the somatosensory pathway involving thalamocortical spindles.

CBD lengthens sleep, shortens ripples and leads to intact simple but worse cumulative memory

This study shows CBD extends sleep and alters NonREM oscillations in rats, improving sleep but impairing cumulative memory consolidation while leaving simple memory unaffected.

Hypothalamic control of noradrenergic neurons stabilizes sleep

The paper investigates the role of hypocretin neurons in stabilizing sleep by examining their interaction with noradrenergic neurons.

Targeted memory reactivation is not more effective during slow wave sleep than sleep stage 2

This study tests if memory reactivation during slow wave sleep (SWS) is more effective than during sleep stage 2 (S2), finding no significant difference in memory performance.

Sleep spindle maturation enhances slow oscillation-spindle coupling

This study examines how sleep spindle maturation affects slow oscillation-spindle coupling across different age groups in children.

Individual differences in information processing during sleep and wake predict sleep-based memory consolidation of complex rules

The paper investigates how individual differences in wake EEG and sleep neurophysiology predict memory consolidation of complex rules in healthy adults.

Targeted memory reactivation during post-learning sleep does not enhance motor memory consolidation in older adults

This study investigates whether targeted memory reactivation during sleep improves motor memory consolidation in older adults, finding no enhancement despite modulation of brain responses to auditory cues.

Sleepiness, not total sleep amount, increases seizure risk

The paper shows that sleepiness, not total sleep amount, increases seizure risk in Drosophila models by identifying the role of sleep-promoting circuits and serotonin receptors.

Sleep and circadian rhythm disruption by NPTX2 loss of function

This study investigates the role of NPTX2 loss of function in sleep and circadian rhythm disruption, showing that NPTX2 KO mice exhibit disrupted circadian rhythms and sleep fragmentation.

Opiate anticipation,opiate induced anatomical changes in hypocretin (Hcrt, orexin) neurons and opiate induced microglial activation are blocked by the dual Hcrt receptor antagonist suvorexant, while opiate analgesia is maintained

This study shows that suvorexant blocks morphine-induced changes in Hcrt neurons, microglial activation, and anticipatory behavior but preserves morphine analgesia.

State dependent constraints on claustrocortical communication and function

This study investigates how claustrum neurons interact with the cortex during different vigilance states, finding that their activity and communication efficacy are modulated by cortical synchronization and cholinergic tone.

Criticality of neuronal avalanches in human sleep and their relationship with sleep macro- and micro-architecture

The paper characterizes neuronal avalanche criticality during sleep and links it to sleep architecture, showing power law distributions and scaling relations consistent with mean-field directed percolation.

The neurophysiology of closed-loop auditory stimulation in sleep: a magnetoencephalography study

This study investigates how closed-loop auditory stimulation during sleep affects brain activity using magnetoencephalography, finding that ventral frontal regions are critical for slow oscillation generation.

Dopamine receptor type 2-expressing medium spiny neurons in the ventral lateral striatum have a non-REM sleep-induce function

This study shows that D2-MSNs in the lateral ventral striatum induce NREM sleep and coordinate with medial VS D2-MSNs in sleep regulation.

Difficulty in artificial word learning impacts targeted memory reactivation and its underlying neural signatures

This study examines how word learning difficulty affects targeted memory reactivation during sleep, finding that easy words benefit more from TMR than difficult ones, with neural correlates in spindle-band power.

Sleep pressure modulates single-neuron synapse dynamics in zebrafish

The paper shows that sleep-dependent synapse loss in zebrafish neurons is regulated by sleep pressure, with synapse gains during wake and losses during sleep, particularly after prolonged wakefulness.

Neural and behavioral organization of rapid eye movement sleep in zebrafish

This study identifies two distinct quiescent sleep states in larval zebrafish, qREM and qNREM, and challenges the scanning hypothesis for REM sleep origin.