J. Ding

Fast inactivation of Na+ current in rat adrenal chromaffin cells involves two independent inactivation pathways

The paper investigates two independent inactivation pathways of Na+ current in rat adrenal chromaffin cells and shows how they contribute to use-dependent changes in Nav availability.

Molecular and morphological analyses clarify species delimitation and reveal a new Betula species in section Costatae

The paper uses molecular and morphological data to clarify species boundaries in Betula section Costatae, identifying a new species, Betula buggsii, within the group.

Multiple glacial refugia across northern and southern China and unexpected patterns of spatial genetic diversity in Betula albosinensis: a widespread temperate deciduous tree species

The paper tests hypotheses about genetic diversity patterns in Betula albosinensis, finding support for the central-marginal hypothesis and the role of multiple glacial refugia.

Identification of Lysine Isobutyrylation as A New Histone Modification Mark

The paper identifies lysine isobutyrylation as a new histone modification mark and shows its role in epigenetic regulation and cellular physiology.

Structure and allosteric regulation of human IDH3 holoenzyme

This study reports the structure of human IDH3 holoenzyme and identifies key residues and domains involved in its assembly and allosteric regulation.

Bidirectional introgression between Betula tianshanica and Betula microphylla and its implications for conservation

The paper uses molecular markers and ecological niche models to study introgression between Betula tianshanica and Betula microphylla, finding bidirectional gene flow with implications for conservation.

Spatial and functional links between cellular virological state and progression of liver fibrosis in chronic hepatitis B

This study links cellular virological stages in chronic hepatitis B to liver fibrosis progression through spatial and functional analysis of viral and host gene expression.

Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment

This study shows that β-adrenergic receptor signaling regulates cardiomyocyte cytokinesis, and β-blockers like propranolol can enhance division in ToF/PS cardiomyocytes, potentially improving heart function in CHD patients.

Phenological matching drives wheat pest range shift under climate change

This study shows that climate change has caused a northward shift in the range of wheat pests, leading to increased crop damage despite pesticide use.

HBEGF+ macrophages identified in rheumatoid arthritis promote joint tissue invasiveness and are reshaped differentially by medications

A newly identified human macrophage phenotype in RA promotes joint tissue invasiveness and shows variable responses to anti-inflammatory medications.

Shigella flexneri adherence factor expression in in vivo-like conditions

This paper shows that Shigella flexneri expresses adherence factors under in vivo-like conditions, challenging previous assumptions about its inability to produce traditional adherence factors.

Exosomes exploit the virus entry machinery and pathway to transmit IFN-α-induced antiviral activity.

This study identifies TIM-1 and endocytic pathways as key mediators of exosome entry and cargo delivery for IFN-α-induced antiviral activity transfer from macrophages to hepatocytes.

Physiological and transcriptome analysis of indica rice ‘MH86’ overexpressing OsSPL14

This study shows that overexpressing OsSPL14 in rice leads to shorter growth period, altered leaf morphology, and changes in hormone levels and culm composition.

Structural basis and mechanism of the unfolding-induced activation of an acid response chaperone HdeA

This study uses NMR to reveal the structural basis of HdeA activation under acidic conditions, identifying key disordered regions and client binding sites.

A potential role for epigenetic processes in the acclimation response to elevated pCO2 in the model diatom Phaeodactylum tricornutum

This study examines transcriptomic changes in the diatom Phaeodactylum tricornutum under elevated pCO2, finding down-regulation of chromatin structure genes and up-regulation of histone acetylation enzymes and transposable elements.

A major locus controls local adaptation and adaptive life history variation in a perennial plant

The paper identifies a major genetic locus, PtFT2, that controls local adaptation and adaptive life history variation in European aspen across a latitudinal gradient.

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

This study identifies 535 novel genetic loci associated with blood pressure traits in over one million individuals of European ancestry.