X. Sun

This study identifies a new structural class of fungal effectors in Fusarium oxysporum f. sp. lycopersici using experimental and computational methods, revealing structural relationships and immune recognition mechanisms.

This paper tests a computational model's ability to generalize from visual to olfactory navigation in insects and shows how a neural mechanism enables robust navigation across sensory inputs.

This paper develops a type 2 diabetes model in nude athymic rats using high-fat diet and streptozotocin, showing features of diabetic cardiomyopathy suitable for xenograft studies.

This study shows that loss of Nrd1 function in tomato enhances resistance to Pseudomonas syringae pv. tomato by suppressing the defense gene Agp1.

This study identifies TRIM67 as an oncogene in oligodendrogliomas that promotes cell motility, tumor growth, and membrane blebbing through Rho GTPase/ROCK signaling.

This study identifies AI-2 as a quorum sensing signal that inhibits sporulation in Bacillus velezensis SQR9 by interacting with RapC and ComA, revealing a population-level regulatory mechanism.

This study investigates how grafting affects anthocyanin synthesis in grapevines by analyzing metabolomic and transcriptomic profiles across different grafting conditions.

This study shows that CD147 antibody inhibits SARS-CoV-2 infection and cytokine storm in variants by blocking viral entry and reducing inflammatory responses.

This paper develops a cellulose-based method using nanobodies to capture and neutralize SARS-CoV-2 pseudoviruses, showing effectiveness against wildtype and D614G variants.

This paper improves the production of disulfide-bonded fungal effectors in E. coli using CyDisCo and FunCyDisCo co-expression systems, enabling functional studies and crystallisation.

The paper investigates the relationship between antagonism and phylogeny in Bacillus by analyzing biosynthetic gene clusters (BGCs) and finds a positive correlation between BGC distance and phylogenetic distance.

The paper uses machine learning to predict DNA sequences that create strong optical responses to serotonin in DNA-carbon nanotube sensors, discovering five new sensors with improved performance.

This study presents a chromosome-scale spinach reference genome and resequences 305 accessions to explore evolution, domestication, and genetic basis of agronomic traits.

This paper develops a novel PROTAC, ZL216, using an aptamer as a targeting ligand to selectively degrade nucleolin in breast cancer cells, inhibiting their proliferation and migration.

This study shows that Bacillus velezensis SQR9 uses a type VII secretion system to acquire iron from plant roots, enhancing its colonization.

This study identifies host cell master regulators affected by SARS-CoV-2 and develops a method to find drugs that reverse their inactivation without harming beneficial immune responses.

This study identifies metabolic interactions between Bacillus velezensis and Pseudomonas stutzeri in the cucumber rhizosphere that enhance plant growth and salt stress tolerance.

The paper reviews efforts to create human anatomical structures, cell types, and biomarkers tables and 3D reference organs to support a Human Reference Atlas, with use cases showing their utility in biomedical research.

This study shows that FliW and CsrA regulate flagellin (FliC) synthesis in C. difficile R20291, affecting virulence and physiology through a mechanism similar to the 'FliW-CsrA-Hag' switch in B. subtilis.

The paper maps the central and peripheral projections of lung-innervating sensory neurons, identifying their targets and marker expression.

This study identifies two non-coding A-to-T mutations at the Kozak site of the N gene as potentially contributing to the transmissibility of Alpha, Delta, and Omicron SARS-CoV-2 variants.

The paper investigates how AKR1C and NADH contribute to cis-platin resistance in HepG2 cells using transcriptomic and metabolic analysis.

The paper identifies PD-L1-lncRNA, a long non-coding RNA splice variant of PD-L1, that promotes lung adenocarcinoma progression by enhancing c-Myc activity.

This study develops a method to sequence nearly full-length rRNA genes from environmental samples, achieving high accuracy and coverage in microbial community analysis.

This study identifies AcMNPV orf13 as essential for efficient nuclear egress of nucleocapsids during virion budding but not for occlusion body formation.

This paper develops a chemiluminescence immunoassay for detecting ASFV antibodies in serum, showing high specificity, sensitivity, and consistency with a commercial kit.

This study engineers the STING protein as a delivery system to enhance CDN delivery and restore STING signaling in cancer cells.

This study quantitatively examines how glycosyltransferases remain in the Golgi by analyzing their post-Golgi trafficking and identifying retention mechanisms through chimeric protein analysis.

This study identifies MAP2 phosphorylation changes in schizophrenia, linking them to neuronal structure and synaptic function impairments through phosphoproteomics and transgenic mouse models.

The paper shows that bacterial DNA recombination increases tRNA levels early in antibiotic stress, aiding resistance before efflux pumps or mutations.