Z. Zhang

This study shows that UTX promotes glioblastoma progression by upregulating periostin expression, and its knockdown inhibits tumor growth and promotes apoptosis.

This paper identifies CaMK1D as a key mediator of ghrelin-induced food intake in AgRP neurons, showing its role in promoting orexigenic neuropeptide expression and obesity resistance.

This study identifies how Omicron evades neutralizing antibodies by analyzing mutations and their effects on different epitope groups, showing over 85% of tested antibodies are escaped.

This study shows MAL suppresses OSCC by maintaining epithelial differentiation, with MAL and its co-functional genes as potential biomarkers for prevention and therapy.

This study shows dihydroartemisinin (DHA) enhances anti-PD-1 therapy in hepatocellular carcinoma by inhibiting YAP1 and disrupting immune evasion through PD-L1, JAK1/STAT1, and JAK3 pathways.

The paper improves the reference genome annotation of Brassica rapa using PacBio RNA sequencing, identifying novel genes, correcting splicing errors, and characterizing alternative splicing and lncRNAs.

This study shows that SVP interacts with TPL to repress flowering by inhibiting FT gene expression in chrysanthemum and Arabidopsis, highlighting a conserved mechanism across species.

This study identifies Nrf2/FAM134B-mediated ER-phagy as a protective mechanism against oxidative damage in intervertebral disc degeneration.

The paper identifies a conserved CTL epitope in the SARS-CoV-2 spike protein that is compatible with most HLA alleles and suitable for evaluating CD8+ T cell responses.

The paper investigates age-dependent H3K9 acetylation changes in rice flag leaf senescence, finding increased H3K9ac levels correlate with gene expression and identify regulatory networks.

A third dose of inactivated SARS-CoV-2 vaccine significantly enhances plasma neutralization and generates high-affinity anti-RBD memory B cells against variants like Beta, Delta, and Lambda.

The paper introduces a cost-effective flat-field illumination module for TIRF-based super-resolution microscopy to address uneven illumination issues.

The paper identifies PIRAT, a lncRNA regulating monocyte immunity in COVID-19 via PU.1 feedback, and shows its role in alarmin production.

The paper investigates the role of parthenogenetic Asian longhorned ticks in spreading SFTSV, finding they contribute to rapid spread and long-range movement.

This study shows inhibiting ferroptosis reduces MHV-A59 infection by suppressing viral propagation and inflammation.

This study identifies increased RNA polymerase II pausing as a mechanism of acquired radiotherapy resistance in cancer cells and suggests CDK7 inhibitors as a potential therapeutic strategy.

The paper identifies a Klebsiella strain from the gut of Spodoptera frugiperda larvae that degrades PVC, using multi-omics to characterize the degradation pathway.

This paper shows metformin reduces anxiety and depression-like symptoms in mice during methamphetamine withdrawal by modulating gut microbiota-derived inosine.

This study shows that loss of Nrf1, not Nrf2, causes lipid and ROS accumulation in hepatoma cells, which can be reduced by 2-bromopalmitate.

This study shows that Celastrol reduces colitis by modulating gut microbiota, improving immune balance, and increasing metabolites like pyruvate and adenosine.

This study shows that CD147 antibody inhibits SARS-CoV-2 infection and cytokine storm in variants by blocking viral entry and reducing inflammatory responses.

This study shows that defective endosome-TGN retrograde transport enhances NLRP3 inflammasome activation in macrophages, leading to increased inflammation and susceptibility to sepsis.

The paper identifies CDC20 missense variants linked to familial cancer, showing they impair SAC binding and promote mitotic slippage.

This study identifies SNP markers associated with salt tolerance traits in upland cotton through genome-wide association analysis.

This study identifies on-target point mutations caused by CRISPR-Cas9 in yeast, showing sequence dependence and involvement of NHEJ components.

This study investigates how kinesin binding induces directional asymmetry in microtubule structure through long-range allosteric effects, explaining the directionality of kinesin stepping.

This study identifies CaMYB101 as an anthocyanin biosynthesis repressor in pepper through genome-wide R2R3-MYB analysis and virus-induced gene silencing.

This study examines correlations between SNPs in 13 language genes and culture/education parameters across 26 countries using PCA.

This study identifies STK11IP as a lysosome-specific mTORC1 substrate that regulates lysosomal acidification and autophagy, with implications for therapeutic targeting of autophagy-related diseases.

The paper tests how combined nutrient and light availability affect alien plant competitiveness and finds that multiple resources increase alien plant dominance over natives.