J. Li

This study shows that DeltaNp63 is essential for maintaining epidermal homeostasis, stemness, and inflammation suppression in adult skin, with its loss causing psoriasis-like inflammation and impaired wound healing.

This paper identifies a 4-bp deletion in the maize ZmSOS1 gene that causes salt sensitivity and develops a molecular marker to improve salt tolerance in breeding programs.

The paper identifies native peptide substrates for bacterial Hsp70 DnaK, finding conserved and divergent binding properties among them, with VP5 showing potential as an antibacterial lead.

This study identifies ZmGL8 as a key gene regulating the balance between cuticular wax production and jasmonic acid-mediated defenses in maize, showing its role in modulating plant defense responses.

This study shows that pacsin 2 regulates N-cadherin internalization, affecting collective migration of bladder cancer cells.

This study shows that mitochondrial dysfunction triggers a retrograde signaling program that reduces cellular maturity in metabolic tissues, and blocking this signaling can restore cell identity and improve hyperglycemia.

This paper develops multispecific antibodies that neutralize all SARS-CoV-2 variants, including Omicron, by targeting multiple epitopes on the spike protein.

The paper identifies a post-translational mechanism where Nardilysin cleaves Plk3 to generate an active form that suppresses pancreatic cancer development and metastasis.

The paper develops an agent-based model to predict pollen deposition in a dioecious crop by integrating plant-pollinator interactions and management scenarios.

This paper identifies Marinifilaceae bacteria as key players in deep-sea organic matter mineralization, revealing their metabolic versatility and role in carbon and nitrogen cycling.

This study shows that p53 restoration in SCLC can induce necrosis via cyclophilin-dependent mechanisms, revealing subtype-specific responses and potential therapeutic targets.

This study identifies CD47 as a regulator of insulin secretion and islet transplant outcomes, showing that its inhibition enhances insulin release and transplant efficiency.

The paper generates and analyzes an mcr-1 mutant library to assess the impact of mutations on colistin resistance, finding that most mutations in the catalytic domain reduce resistance.

This paper identifies FcγRIIB-mediated capture of antibody-coated bacteria by liver sinusoidal endothelial cells as a mechanism for superior vaccine efficacy.

The paper investigates how IFN-gamma-secreting CD4+ T-cells alter the transcriptional output of IL-6 by redirecting STAT1 and STAT3 to Alu-like retroelements during inflammation.

This study identifies a conserved Trp-Pro motif in PPARγ AF-1 that undergoes cis/trans isomerization, enabling interdomain communication with the LBD and affecting transcriptional activity.

The paper was withdrawn due to duplicate submission and is not intended for citation.

This study examines age-related changes in knee osteoarthritis, pain behaviors, and dorsal root ganglia immune profiles in male and female mice, revealing sex-specific differences in cartilage degeneration and immune cell composition.

This study reports cryo-EM structures of modified IGF1R and IR complexes, showing that disulfide-linked CTs are critical for receptor activation and signaling.

This study identifies FOXP2 as an oncogene in prostate cancer that activates MET signaling, promoting tumorigenicity through both full-length and truncated forms.

This study creates 3D printed neural tissues with embedded optical dopamine sensors and demonstrates their ability to detect dopamine with high sensitivity.

This study demonstrates the safety of synthetic oxidized β-carotene (OxBC) in rats and shows its uptake and distribution in mice tissues.

This study shows that inhibiting EZH2 enhances pro-inflammatory SASP in pancreatic cancer, improving NK and T cell infiltration and tumor control in mouse models.

An intranasal SARS-CoV-2 beta variant subunit booster vaccine induced protective immunity against beta variant infection in rhesus macaques one year after initial vaccination.

This study combines transcriptome and metabolome analysis to identify molecular responses of Desmodesmus sp. to sewage treatment, revealing key pathways and metabolite changes.

This study investigates the effects of FABP1 and FAS overexpression on collagen III and cross-linking in Zongdihua pig tissues, identifying their roles in fat deposition.

This study shows that benzo(a)pyrene induces chaperone-mediated autophagy (CMA) and DNA damage through heat shock protein 90 (HSP90) in lung cells.

The paper investigates subtype-specific mechanics of β1 integrins in cell spreading, showing different tension thresholds and cytoskeletal remodeling for integrin α4β1 versus RGD-binding integrins.

This study shows that deep learning-based contact map predictions can capture structural information of multiple states, enabling exploration of alternative conformations of a known protein structure.

This study demonstrates that optical modulation of the blood-brain-tumor barrier enhances drug delivery and suppresses tumor growth in glioblastoma models.