T. Wang

This study develops an FcRn-targeted mucosal vaccine that reduces SARS-CoV-2 infection and transmission in mice and hamsters by inducing protective immune responses in the airways.

The paper maps single-cell lysis probabilities to population-level biomass dynamics during antibiotic treatment, showing how filamentation extent influences lysis and validates this with experiments.

This study examines renal markers in autoimmune diseases, finding that autoantibodies significantly affect marker levels and are more frequent in severe renal damage.

This study examines the prevalence and risk factors of HIV-1 associated thrombocytopenia and its link to neuroinflammation in a hospital in western China.

This study develops a computational pipeline combining metagenomics and metaproteomics to identify proteins' metabolic and ecological roles in gut microbiomes using simulated and real data.

The paper presents a single-cell transcriptomic atlas of human inner ears, revealing increased regeneration in diseased utricles and new cell type markers.

This study identifies and characterizes long non-coding RNAs (lncRNAs) in Plasmodium falciparum, revealing their role in gene regulation, pathogenicity, and sexual differentiation.

This study identifies recurrent DNA methylation alterations in primary non-small cell lung cancer samples from smokers and never-smokers, highlighting differences in hypomethylation patterns and their association with oncogenes and transcription factor binding motifs.

The paper evaluates DLP 3D printing for PDMS microfluidics, optimizing parameters and demonstrating applications in cell viability, drug response, concentration gradients, and live-cell invasion.

This study identifies SAID1/2 as negative regulators of miRNA biogenesis in Arabidopsis by inhibiting the microprocessor complex through phase condensation and SE degradation.

The paper shows that embryonic vitamin D deficiency in HSCs leads to diabetes in mice by altering epigenetic pathways and macrophage function.

This study identifies mitochondrial Ca+2 dysregulation via MAM-STAT3 as a driver of immunosenescence in type A mandibuloacral dysplasia.

This study identifies Tmem100 as a lung-specific endothelial gene through single-cell RNA-sequencing analysis.

This paper introduces snPATHO-Seq, a method for high-quality single nucleus RNA sequencing from FFPE samples, showing improved sensitivity and accuracy compared to existing methods.

This study shows that asparagine restriction induces a biphasic response in CD8 T cells, enhancing their metabolic fitness and antitumoral function through ATF4/NRF2-dependent mechanisms.

The paper was withdrawn due to insufficient cell culture data to clarify the mechanism of ticagrelor and aspirin's effect on the gut microbiome and immuno-inflammatory response in atherosclerosis.

The paper shows that gut microbiota balance immune responses in neonatal lungs, promoting recovery from pneumonia by modulating tissue repair and inflammation.

This study characterizes the entry mechanisms and antibody neutralization resistance of Omicron variants BA.1, BA.1.1, BA.2, and BA.3 compared to the D614G strain.

The paper integrates single-cell RNA and protein data from breast cancer samples to identify novel lymphocyte phenotypes and their clinical relevance.

This study examines how a breast cancer-associated mutation in CAV1, P132L, affects its structure and oligomerization, revealing its impact on caveolae formation.

The paper introduces PERSIST, a deep learning framework that selects optimal gene panels for spatial transcriptomics using scRNA-seq data, improving prediction accuracy and generalization across technologies.

This paper introduces a chemical derivatization method using N-Me aziridination to precisely identify C=C bond positions in lipids via mass spectrometry.

This paper develops a DNA vaccine targeting dendritic cells that enhances isoniazid efficacy against tuberculosis by inducing strong immune responses and reducing Mtb burden.

The paper investigates how acetylation reading and writing enable long-range chromosomal interactions through the BRD4-NUT oncogenic fusion protein and p300 activation.

The paper develops a consumer-resource model to show that thermodynamic constraints drive functional convergence in slow-growing microbial communities, validated by experimental data from anaerobic digesters.

This study shows that alveolar regeneration after viral infection occurs independently of tuft cells, with ectopic basal progenitor cells generating alveolar epithelial cells through distinct differentiation paths.

This study compares the chemo-mechanical properties of cardiac ventricular and slow skeletal myosins with the same heavy chain isoform, finding distinct kinetic and mechanical behaviors.

The paper shows that MLC1sa in soleus myosin slows actin gliding compared to MLC1sb/v in ventricular myosin, likely due to increased actin affinity and reduced dissociation rate.

The paper investigates how alternative 3' UTRs regulate gene expression in response to high salt stress in Spartina alterniflora, showing that 3' UTR lengthening enhances RNA stability and protein synthesis of stress-related genes.

This study identifies how residual triple negative breast cancer cells adapt mitochondrial structure and function to survive chemotherapy, showing that DNA-damaging agents promote mitochondrial fusion and OXPHOS, which can be targeted with OPA1 inhibitors.