Z. Sun

The paper evaluates an antibody domain's ability to neutralize SARS-CoV-2 variants with mutations in the RBD, showing it neutralizes the triple mutation variant but not others.

This study shows that a low sugar diet increases body size in both male and female Drosophila larvae, but affects their insulin/TOR signaling and metabolism differently.

This study shows sulfur limitation increases duckweed starch yield without reducing growth, making it a promising method for biofuel production.

This study identifies MAP2 phosphorylation changes in schizophrenia, linking them to neuronal structure and synaptic function impairments through phosphoproteomics and transgenic mouse models.

This study shows that lauric acid intake leads to endogenous production of DLPC, an LRH-1 ligand, and enhances LRH-1 transcriptional activity in multiple tissues.

This paper introduces 2bRAD-M, a low-cost metagenome-sequencing method that enables species-level microbial profiling of low-biomass and degraded samples with high accuracy.

The paper builds a comprehensive Pseudomonas aeruginosa PeptideAtlas with high proteome coverage, providing a valuable resource for proteomic studies of this pathogen.

This study identifies widespread sigma70-dependent promoter-proximal pausing in E. coli regulated by Gre factors through NET-seq and RNase I footprinting.

The paper identifies a suboptimal-health gum state (SoH) during experimental gingivitis, characterized by microbiome and metabolite changes similar to periodontitis.

This study shows that altering insulin/insulin-like growth factor signaling (IIS) activity in Drosophila larvae has sex-biased effects on body size, with inhibition reducing female size more than males and augmentation increasing male size more than females.

This paper develops a deep learning system for gastric cancer detection using histopathological images, achieving high sensitivity and robust performance across different scanners.

This study shows that the S1/S2 boundary of the SARS-CoV-2 spike protein affects cell entry and transmission by altering the pathway used for viral entry.

The paper shows that the N34S mutation in SPINK1 reduces its inhibitory efficiency, leading to earlier trypsin release in the pancreas due to kinetic effects and autocatalytic conversion.

This study uses PacBio sequencing to analyze milk microbiota from healthy and mastitis cows, finding significant differences in diversity, richness, and composition, and develops a predictive model for mastitis risk.

This study shows that activating CAR with HBx in mice leads to liver tumors with strong β-catenin activation, mirroring human HBV-related HCC.

HiFi-SIM improves structured illumination microscopy image fidelity by reducing artifacts and enhancing axial resolution without requiring precise PSF calibration or parameter tuning.

This study shows that immunization with SARS-CoV-2 RBD induces antibodies that neutralize both SARS-CoV-2 and SARS-CoV without causing antibody-dependent enhancement.

This study identifies FSTL1-expressing adipocyte progenitors as drivers of age-related brown adipose tissue involution in rabbits and humans, with loss of FSTL1 causing iBAT atrophy in mice.

This study rapidly identifies a potent human monoclonal antibody against SARS-CoV-2 that neutralizes the virus in animal models and shows promise for therapeutic use.

This study identifies Ppd-1's role in regulating floral development and spike architecture in wheat, linking it to grain yield through phenotypic and transcriptomic analyses.

This study shows that protoporphyrin IX and verteporfin inhibit SARS-CoV-2 infection in vitro and in a human ACE2-expressing mouse model by blocking ACE2-S protein interaction.

The paper characterizes the biochemical diversity of CRISPR-Cas9 orthologs, identifying varied PAM recognition and gRNA requirements across 79 Cas9 proteins.

The paper identifies a female-specific increase in insulin pathway activity as the mechanism behind sex differences in nutrient-dependent body size plasticity in Drosophila.

The paper develops CAR-expressing iPSC-derived macrophage cells with antigen-dependent anti-cancer functions effective against both liquid and solid tumors.

This study uses a CRISPR screen in mouse Tregs to identify genes regulating Foxp3 expression, finding Usp22 and Atxn7l3 as stabilizers and Rnf20 as a destabilizer.

This study uses AFM to examine how PriA helicase interacts with stalled DNA replication forks in the presence or absence of SSB, revealing specific binding preferences and remodeling roles.

This study shows that Coxiella burnetii phase II can grow under normoxic conditions in ACCM-2 with tryptophan, and its transformant grows robustly without tryptophan, suggesting tryptophan and a temperature-sensitive signal are involved in normoxic growth.

The paper shows that iron-deficiency and estrogen increase transferrin, leading to hypercoagulability and worsened ischemic stroke.

This study uses bibliometric analysis to examine soil remediation research trends from 1988-2018, identifying key topics and institutional contributions.

The paper uses solid-state NMR to study a constitutively open mutant of KcsA, finding reduced potassium binding affinity at the selectivity filter, supporting allosteric coupling in C-type inactivation.