Gut microbiota and health

Evolutionary history and microbial cross-feeding shape lifestyle-stratified dominance of Bifidobacterium longum subspecies in infants

The paper analyzes the evolutionary history and microbial interactions of Bifidobacterium longum subspecies in infants, finding that subspecies distribution is shaped by ecological factors and cross-feeding rather than host-specific factors.

Sex-dependent effects of a glutamine supplementation on metabolic disorders, intestinal barrier function and gut microbiota in mice with diet-induced obesity.

This study examines sex-dependent effects of glutamine supplementation on metabolic disorders, intestinal barrier function, and gut microbiota in diet-induced obese mice, finding protective effects in males and harmful effects in females.

Infant acquisition of Stickland-metabolizing bacteria prevents Clostridium botulinum infection

The paper shows that infant acquisition of Stickland-metabolizing bacteria prevents Clostridium botulinum infection by competing for amino acids.

Gut Microbiome Alterations in Canine Idiopathic Epilepsy: A Pairwise Case-Control Study

This study compares gut microbiomes of dogs with idiopathic epilepsy and healthy controls, finding a significant shift in microbial composition associated with epilepsy.

Early-life antibiotic exposure leads to gut microbial dysbiosis associated with neurodevelopment and neuroregeneration

This study shows that early-life antibiotic exposure disrupts gut microbiota and metabolites, which negatively affect neurodevelopment and neuroregeneration in offspring.

Integrative metagenomics and structural bioinformatics identify explainable gut microbial variants associated with Crohns disease

Senescence-associated loss of intestinal α1,2-fucose disrupts a modifiable host-microbiome homeostasis axis in people with HIV

This study identifies loss of intestinal 1,2-fucose in HIV-treated individuals as a modifiable host-microbiome mechanism linked to inflammation, barrier dysfunction, and aging.

Human gut flagellome profiling using FlaPro reveals TLR5-related phenotype-specific alterations in IBD

The paper introduces FlaPro, a tool to profile the human gut flagellome, revealing TLR5-related changes in IBD patients.

Gut microbiota promote early-life digestive function in songbirds

This study shows that gut microbiota colonization is essential for digestive development in House sparrows, increasing intestinal structure and function.

Early-life acquisition of Lactobacillaceae protects against experimental cholera

This study shows that early-life acquisition of Lactobacillaceae bacteria protects neonatal mice from experimental cholera by reducing V. cholerae colonization.

PFOS aggravates atherosclerosis via Bacteroides caecimuris expansion-driven bile acid remodeling and subsequent intestinal FXR-TLR3 signaling cascade

This study shows PFOS worsens atherosclerosis by expanding Bacteroides caecimuris, altering bile acids, and activating FXR-TLR3 signaling in the gut.

Isolation and characterization of microbiota from human pancreatic tumors and small intestine

This study isolates and characterizes microbiota from human pancreatic tumors and small intestine, revealing how a Klebsiella oxytoca strain affects the tumor microenvironment and therapy response.

Distinct colorectal cancer genotypes shape microbial ecosystems and reveal stage-specific microbiota dependencies

This study shows that different colorectal cancer genotypes create distinct microbial ecosystems and that microbiota dependence decreases as tumors progress.

The mouse gut microbiota responds to predator odor and predicts host behavior

This study shows that predator odor exposure alters mouse gut microbiota, which predicts host behavior through gene expression and microbial interactions.

Maternal effects shape scale-dependent convergence in gut microbial responses to environmental change

This study examines how gut microbial communities in red squirrels respond to seasonal variation and episodic resource pulses, finding that maternal effects influence microbial convergence during resource pulses but not seasonal changes.

Females Adapt to Dietary Protein Restriction on Enhanced Gut-Brain Axis during Aging

This study shows that dietary protein restriction improves metabolic and cognitive health in aged female mice by altering the gut microbiome.

MAAMOUL: Metabolic network-based discovery of microbiome-metabolome shifts in disease

MAAMOUL identifies disease-associated microbial metabolic modules by integrating metagenomic and metabolomic data through a metabolic network framework.

IBD stress impacts gut microbiome intra-species diversity

The paper investigates how IBD stress affects intra-species diversity in the gut microbiome, finding species- and function-specific genetic changes associated with motility and iron-scavenging.

Genome-scale metabolic models predict diet- and lifestyle-driven shifts of ecological interactions in the gut microbiome

The paper uses genome-scale metabolic models to predict how diet and lifestyle affect microbial interactions in the gut microbiome, finding shifts from collaboration to competition with high sugar intake.

Two Key Actinomycetota Taxa in the Human Gut Microbiota are Associated with Schistosoma mansoni Infection Burden

Oral and gut microbiomes reveal latent physiological constraints on release readiness in rehabilitating Javan slow lorises

The paper assesses oral and gut microbiomes in Javan slow lorises to evaluate release readiness, finding oral microbiome changes correlate with dental perturbations.

Cadmium toxicity to the human gut microbiome varies depending on composition

This study examines how human gut microbiomes respond to cadmium exposure, identifying distinct responses based on microbial composition and highlighting the role of Anaerostipes in Cd resilience.

Uncoupling Drug and Microbiota Contributions to Chemotherapy-Induced Gut Toxicity

This study shows that both chemotherapy drugs and altered gut microbiota independently damage the intestinal barrier, but through different host transcriptional pathways.

Industrialization restructures the domestic dog gut microbiome while preserving host specificity

This study examines how industrialization affects the gut microbiome of domestic dogs across different lifestyles and finds that lifestyle is the strongest correlate of microbiome composition, with industrialization causing directional genus-level turnover and shifts in functional potential.

MeLSI: Metric Learning for Statistical Inference in Microbiome Community Composition Analysis

MeLSI learns data-adaptive distance metrics for microbiome community composition analysis, improving detection of biologically meaningful differences compared to fixed metrics.

Unveiling correlational nexus among environment, gut microbiota, and personality traits in the Iberian Lynx (Lynx pardinus)

This study examines the relationship between gut microbiota, behavior, and environment in captive Iberian lynxes, finding associations between microbial profiles and personality traits.

Gut microbiome composition and predicted functions relate to growth and behavior in a Japanese preschool cohort

The paper links gut microbiome composition and predicted functions to growth and behavior in Japanese preschool children, showing distinct microbial signatures for different behavioral domains.

Fragmented gut-airway microbial networks and airway Moraxella clusters in preschool wheeze

This study compares nasal and stool bacterial communities in preschool wheezers and healthy controls, finding fragmented microbial networks and Moraxella enrichment in wheezers despite similar overall diversity.

Gut Microbiota Dysbiosis and Short-chain Fatty Acid alterations in Pediatric New-Onset Type 1 diabetes with Ketoacidosis

This study examines gut microbiota and short-chain fatty acid (SCFA) levels in children with new-onset type 1 diabetes (T1D) with and without diabetic ketoacidosis (DKA), finding reduced SCFAs and SCFA-producing bacteria in DKA patients.

Dominance of metabolically flexible fermenters drives intestinal gas production in Crohn's disease

The paper identifies metabolically flexible fermenters as drivers of increased intestinal gas production in Crohn's disease by analyzing microbial genomes and metagenomes.