Salmonella and Campylobacter epidemiology

Distinct adaptation and epidemiological success of different genotypes within Salmonella enterica serovar Dublin

This study analyzes the genomic and epidemiological differences between two Salmonella Dublin lineages, revealing distinct adaptations that influence their success in different regions.

Genetic diversity and antimicrobial resistance of Campylobacter jejuni isolates from Gambian children under five with moderate-to-severe diarrhoea and healthy Controls

This study analyzes the genetic diversity and antimicrobial resistance of Campylobacter jejuni isolates from Gambian children with diarrhoea and healthy controls, finding high genotypic diversity and low-level antibiotic resistance.

Harnessing the pangenome for genomic surveillance: Salmonella enterica serotype Typhi as a paradigm

The paper introduces a method to measure pangenome relatedness using Jaccard Index and a novel distance metric to capture both vertical and horizontal gene transfer in Salmonella Typhi, enhancing genomic surveillance.

CemR atypical response regulator impacts energy conversion in Campylobacteria

The paper shows that CemR regulates metabolic pathways in Campylobacteria to adapt to oxygen availability, impacting ATP production and growth.

From Acute to Persistent Infection: Revealing Phylogenomic Variations in Salmonella Agona

The paper examines phylogenomic variations in Salmonella Agona during acute and persistent infections, finding increased genome rearrangements and SNP variation in early carriage.

Structure classification of the proteins from Salmonella enterica pangenome revealed novel potential pathogenicity islands

The paper classifies proteins from Salmonella enterica pangenome, identifies potentially pathogenic proteins, and reveals their clustering in the genome.

Evolutionary and functional connections between the typhoid toxins encoded by S. Typhi and S. bongori

This study examines the evolutionary and functional links between typhoid toxins from S. Typhi and S. bongori, showing that S. Typhi's toxin is more potent in infecting human cells when derived from S. bongori.

Healthy carriage of Salmonella within cattle lymph nodes is a key source of ground beef contamination with strains of clinical significance

This study examines Salmonella strains from cattle lymph nodes and ground beef, finding genetic links between them and public health risks.

Widespread dissemination of ESBL-producing Salmonella enterica serovar Infantis exhibiting intermediate fluoroquinolone resistance and harboring blaCTX-M-65-positive pESI-like megaplasmids in Chile

This study sequenced 396 Salmonella Infantis genomes from Chile, revealing widespread dissemination of MDR isolates associated with ESBL-producing plasmids and intermediate fluoroquinolone resistance across multiple niches.

Global diversity and evolution of Salmonella Panama, an understudied serovar causing gastrointestinal and invasive disease worldwide: a genomic epidemiology study

This study analyzes 836 Salmonella Panama genomes to reveal population structure, antimicrobial resistance, and genetic markers of invasiveness across global regions.

The spread of pESI-mediated extended-spectrum cephalosporin resistance in Salmonella serovars - Infantis, Senftenberg, and Alachua isolated from food animal sources in the United States

This study investigates the origin, prevalence, and evolution of the pESI plasmid in Salmonella isolates from food animals in the US, identifying clusters and tracking the spread of antibiotic resistance genes.

Persistent Salmonella infections in humans are associated with mutations in the BarA/SirA regulatory pathway

The paper identifies mutations in the BarA/SirA regulatory pathway in persistent Salmonella infections, showing they reduce virulence and inflammation.

Salmonella enterica serovar Typhimurium ST313 sublineage 2.2 has emerged in Malawi with a characteristic gene expression signature and a fitness advantage

The paper identifies a new sublineage of Salmonella Typhimurium ST313 in Malawi with a gene expression signature and increased fitness compared to its parent lineage.

Evaluation of Loop-Mediated Isothermal Amplification (LAMP) for Rapid Detection of Campylobacter jejuni

This study evaluates a LAMP assay for rapid detection of Campylobacter jejuni, showing 100% sensitivity and specificity compared to whole-genome sequencing.

bettercallsal: better calling of Salmonella serotypes from enrichment cultures using shotgun metagenomic profiling and its application in an outbreak setting.

bettercallsal identifies multiple Salmonella serotypes from enrichment cultures using shotgun metagenomics, outperforming existing tools in accuracy and throughput for outbreak analysis.

Salmonella injectisome penetration of macrophages triggers rapid translation of transcription factors and protection against cell death

The paper shows that Salmonella uses the SPI-1 injectisome to trigger rapid translation of transcription factors in macrophages, which suppresses inflammation and cell death to aid infection.

Urbanization spreads antimicrobial resistant enteric pathogens in wild bird microbiomes

The paper investigates how urbanization affects the spread of antimicrobial resistant Campylobacter jejuni in wild birds, finding a positive correlation between urban proximity and AMR gene prevalence.

Genomic analysis unveils the role of genome degradation events and gene flux in the emergence and persistence of S. Paratyphi A lineages

The paper analyzes S. Paratyphi A isolates to show genome degradation and gene flux drive lineage evolution, with implications for public health surveillance.

Human variation impacting MCOLN2 restricts Salmonella Typhi replication by magnesium deprivation

The paper identifies genetic variation in MCOLN2 that limits Salmonella Typhi replication via magnesium deprivation in human cells.

Stochastic modeling of the dynamics of Salmonella infection of epithelial cells

This paper develops a stochastic model to simulate Salmonella infection dynamics in epithelial cells, predicting infection rates and bacterial load over time.

Management factors influence Salmonella persistence in reused poultry litter over three successive flocks

This study examines how management practices affect Salmonella persistence in poultry litter across three flocks, finding that copper sulfate may select for metal-resistant strains.

Broiler house environment and litter management practices impose selective pressures on antimicrobial resistance genes and virulence factors of Campylobacter

The paper examines how broiler house environments and litter management practices influence antimicrobial resistance and virulence factors in Campylobacter isolates from chicken flocks.

Multidrug resistance plasmids underlie clonal expansions and international spread of Salmonella enterica serotype 4,,12,i:- ST34 in Southeast Asia

This study investigates the genomic structure and evolution of Salmonella ST34 in Southeast Asia, showing that multidrug resistance plasmids drive its clonal expansion and international spread.

Genomic epidemiology and multilevel genome typing of Australian Salmonella enterica serovar Enteritidis

This study uses multilevel genome typing to analyze Australian Salmonella Enteritidis isolates, finding strong epidemiological links to Asian strains and a local outbreak linked to European isolates.

Large-scale comparative genomics of Salmonella enterica to refine the organization of the global Salmonella population structure

This paper analyzes 180,098 Salmonella genomes to refine genomic typing nomenclature by identifying polyphyletic serovars and proposing a stable population structure based on core genome MLST thresholds.

Spatial-temporal and phylogenetic analyses of epidemiologic data to help understand the modes of transmission of endemic typhoid fever in Samoa

This study analyzes spatial-temporal and phylogenetic data from typhoid fever cases in Samoa to identify transmission patterns and the role of asymptomatic carriers.

Persistence of rare Salmonella Typhi genotypes susceptible to first-line antibiotics in the remote islands of Samoa

This study characterizes the genomic structure and evolutionary history of Salmonella Typhi in Samoa, revealing dominant rare genotypes with low antimicrobial resistance.

Population structure and evolution of Salmonella enterica serotype Typhi in Zimbabwe before a typhoid conjugate vaccine immunization campaign

The paper analyzes the population structure and evolution of Salmonella enterica serotype Typhi in Zimbabwe before a typhoid vaccine campaign, identifying dominant resistant genotypes and their AMR mechanisms.

Multiplex PCR Assay for Clade-typing Salmonella Enteritidis

The paper develops a real-time PCR assay to differentiate Salmonella Enteritidis clades for public health surveillance in resource-limited settings.

Comparative analysis of the caecal tonsil transcriptome in two hen lines experimentally infected with Salmonella Enteritidis

The paper compares gene expression in caecal tonsils of two chicken lines infected with Salmonella Enteritidis to identify genes and pathways associated with differences in bacterial carriage.