Y. Zhang

The paper examines S. commune fruiting bodies and hyphae to confirm the presence of calcium oxalate crystallites, demonstrating biomineralization in this fungus.

The paper develops a framework to quantify DOM-microbe associations under global change, finding that molecular traits and nutrient enrichment influence these interactions differently in subarctic and subtropical climates.

mRNA-1273 boosted nonhuman primates show increased neutralizing antibody responses and protection against SARS-CoV-2 beta variant infection.

The paper identifies a novel Tudor domain in the Sds3 subunit of the Sin3L/Rpd3L complex that binds nucleic acids, expanding the known functions of this HDAC complex.

This study compares bioenergetic properties across mole-rats and comparator species, finding lower respiration and reliance on glycolysis in mole-rats linked to longevity.

This paper develops a novel PROTAC, ZL216, using an aptamer as a targeting ligand to selectively degrade nucleolin in breast cancer cells, inhibiting their proliferation and migration.

This study shows Brsk2 amplifies parasympathetic signals to promote type 2 diabetes by enhancing β-cell insulin secretion in obese mice and associates human BRSK2 variants with metabolic disorders.

This study identifies {beta}{gamma}-CAT as a secretory pore-forming protein that drives macropinocytosis and exosome release to aid water uptake in toads under hypertonic stress.

The paper introduces a database that compiles antibody responses and clinical data from COVID-19 patients for analysis and visualization.

This study investigates neophobia in 10 corvid species, finding species differences and socio-ecological influences on novelty responses across 241 subjects in 10 labs.

This study shows that 1,25(OH)2D3 reduces hepatic insulin resistance in diabetic rats by improving antioxidant status and enhancing AKT/GLUT2 expression.

This study shows GC-derived exosomes induce EMT in peritoneal mesothelial cells via TGF-β1/Smads pathway, enhancing GC cell migration and adhesion.

The paper analyzes transcriptome and metabolome data from plum fruits at different developmental stages to identify pathways and genes associated with fruit color changes.

This study reports a pan-drug-resistant Klebsiella pneumoniae isolate carrying NDM-5 and MCR-8.2 genes, along with chromosomal resistance mechanisms to colistin and tigecycline.

The paper uses single-cell transcriptomics to profile viral receptor expression in masked palm civets, identifying potential tissue tropisms for 132 viruses.

TaBln1 negatively regulates wheat resistance to stripe rust by reducing Ca2+ influx through its interaction with TaCaM3 on the plasma membrane.

This paper demonstrates the use of optical tweezers to manipulate membrane proteins on model membranes, measuring their dynamics with high spatiotemporal resolution.

This study shows that higher precursor abundance of YopE69-77-specific CD8+ T cells explains their dominance over OVA257-264-specific cells during Y. pseudotuberculosis infection.

This paper presents a drug candidate, NANA-Me, that prevents and treats ADAA-based diseases caused by pathogenic anti-spike antibodies in COVID-19 and vaccines.

This study identifies KPNB1 and RUVBL2 as key regulators of NFAT5's unconventional tonicity-dependent nuclear trafficking.

This study classifies wheat WAKs and WAKLs, identifies structural features, and shows that TaWAK75 and TaWAK76b are involved in resistance to Bgt.

The paper screens a fragment-based library to identify inhibitors of Lassa virus endonuclease, finding two benzotriazole compounds that inhibit viral minigenome activity and show synergistic antiviral effects.

This study shows that complete depletion of linker histone H1 in Arabidopsis disrupts correlations between chromatin compartmentalization, DNA methylation, and gene expression.

This study identifies a major QTL on chromosome A09 associated with water-use efficiency and seed yield in Brassica napus, linked to homoeologous exchanges and gene expression differences.

The paper uses structural and sequence data to predict responsiveness to pharmacological chaperone treatment for Gaucher disease variants, finding that protein topology and mutation stability influence treatment effectiveness.

The study tracks IgG antibody levels against SARS-CoV-2 RBD in convalescent plasma donors over 12 months, showing sustained positivity and gender/age-related differences.

The paper introduces an open-source personal pipetting robot compatible with live-cell incubation and microscopy, designed for non-specialists to automate experiments.

This study manually resolves viral dark matter in a large infant gut virome dataset, identifying over ten thousand viral species across 248 families and expanding bacteriophage taxonomy.

This study compares clonal evolution across right-sided colon cancer, left-sided colon cancer, and rectal cancer patients, finding differences in evolutionary patterns and identifying polyclonal origins of lymph node and extranodal tumor deposits.

The paper analyzes T cell responses to SARS-CoV-2 variants and finds minimal impact on CD4+ and CD8+ T cell reactivity in convalescents and vaccinees.