Circadian rhythm and melatonin

Diel and seasonal rhythmicity in activity and corticosterone in an Arctic migratory herbivore: A multifaceted approach

This study examines diel and seasonal rhythmicity in activity and corticosterone in barnacle geese during their Arctic breeding season using a multifaceted approach.

Circadian rhythmicity and reinforcement processing: a dataset of MRI, fMRI, and behavioral measurements

The paper presents a dataset combining MRI, fMRI, and behavioral measurements to study circadian rhythmicity and its relationship with reinforcement processing.

Mapping the Regulatory Architecture of Circadian Clock Adaptation: A Genome-Wide eQTL Analysis in Drosophila melanogaster

The paper identifies eQTLs associated with circadian clock gene expression variation in Drosophila melanogaster using GWAS and the DGRP dataset.

Evolutionary Origins of Self-sustained Kai Protein Circadian Oscillators

The paper investigates the evolutionary origin of self-sustained Kai protein circadian oscillators in cyanobacteria by analyzing ancestral Kai proteins and their functional and structural development.

CK1a-Mediated Two-Step Subunit Remodeling of the Circadian FRQ-FRH Complex

The paper reveals how CK1a-mediated phosphorylation of FRQ leads to a two-step remodeling of the FRQ-FRH complex, enabling precise circadian regulation through temporal decoding of phosphorylation states.

Upstream open reading frames dynamically modulate CLOCK protein translation to regulate circadian rhythm and sleep

This study shows that uORFs in the Clock gene regulate circadian rhythm and sleep by modulating CLK protein translation in Drosophila.

Expression of clock genes tracks daily and tidal time in brains of intertidal crustaceans Eurydice pulchra and Parhyale hawaiensis

The paper identifies circadian and circatidal clock gene expression patterns in the brains of intertidal crustaceans, revealing conserved neural networks for daily and tidal rhythms.

The cellular mammalian clock regulates Staphylococcus aureus invasion in epithelial cells

This study shows that the host circadian clock modulates Staphylococcus aureus invasion into epithelial cells via the SraP-GP340 pathway.

Light and sex modify Snord116 genotype effects on metabolism, behavior, and imprinted gene networks following circadian entrainment

The paper examines how Snord116 genotype interacts with light and sex to influence metabolism, behavior, and imprinted gene networks in mice after circadian entrainment.

Full-length Cryptochrome 1 in the outer segments of the retinal blue cone photoreceptors in humans and great apes suggests a role beyond transcriptional repression

The paper detects full-length CRY1 protein in blue cone photoreceptors of human and great ape retinas, suggesting non-clock functions and potential isoform diversity.

Sexually Dimorphic Circadian Regulation of Eclosion and Clock Gene Expression in a Migratory Moth Spodoptera frugiperda

This study examines circadian regulation of eclosion and clock gene expression in Spodoptera frugiperda, finding sexually dimorphic patterns in timing and gene expression.

Environmental and molecular noise buffering by the cyanobacterial clock in individual cells

The paper shows how the cyanobacterial clock buffers noise through its core phosphorylation loop, using single-cell analysis and a stochastic model.

Ancient cyanobacterial proto-circadian clock adapted to short day-night cycles ~ 0.95 billion years ago

The paper reconstructs an ancient cyanobacterial circadian clock from ~0.95 billion years ago and shows it adapts to 18-h day-night cycles but lacks endogenous oscillation.

Discrete photoentrainment of mammalian central clock is regulated by bi-stable dynamic network in the suprachiasmatic nucleus.

The paper identifies discrete light responses in SCN neurons and proposes a bi-stable network model for circadian photoentrainment in mammals.

Evolution of pineal non-visual opsins in lizards and the tuatara (Lepidosauria)

The paper identifies a novel opsin gene, OPNLEP, in lepidosaurs and shows its correlation with the presence of a parietal eye and losses of non-visual opsins in certain lizard clades.

Single-Cell Multiomic Analysis of Circadian Rhythmicity in Mouse Liver

This study uses single-nucleus multiomics to analyze circadian rhythms in mouse liver, revealing gene expression and chromatin accessibility patterns across the day.

Light Impact on Thalamo-Cortical Connectivity During a Cognitive Task Depends on Time of Day and is Different in Teenagers

This study shows that light affects thalamo-cortical connectivity during a cognitive task, with differences based on time of day and age group.

Coevolution of Drosophila-type Timeless with Partner Clock Proteins

This study analyzes the evolution of Drosophila-type timeless across animals, identifying key sequence changes and their association with loss of clock proteins.

An integrative approach prioritizes the orphan GPR61 genomic region in tissue-specific regulation of chronotype

This study identifies a genetic correlation between chronotype and ease of getting-up, prioritizing the GPR61 locus and variant rs12044778 through colocalization and functional analysis.

Circadian Coupling Orchestrates Cell Growth

This study shows that extracellular circadian communication coordinates the circadian clock and cell cycle, and its disruption impairs tissue growth and links circadian disruption to oncogenic processes.

Molecular basis underlying specific interaction of mammalian melanopsins with an antagonist AA92593

This study identifies five amino acid residues in mammalian melanopsins responsible for the specific interaction with the antagonist AA92593.

Lack of circadian entrainment and limited nocturnal plasticity in response to a cyclic aversive stimulus in a diurnal rodent, the antelope ground squirrel (Ammospermophilus leucurus)

This study shows that diurnal antelope ground squirrels do not shift their activity patterns in response to cyclic aversive stimuli, unlike nocturnal rodents.

Hsp90 buffers behavioral plasticity by regulating Pdf transcription in clock neurons of Drosophila melanogaster

This study shows HSP83 regulates Pdf transcription in clock neurons, affecting behavioral plasticity and circadian rhythms in Drosophila under stress.

Melatonin Protects Against Palmitate-Induced Lipid Accumulation and Leptin Resistance via PI3K/AKT in 3T3-L1 Cell line

This study shows melatonin reduces lipid accumulation and leptin resistance in 3T3-L1 cells by activating PI3K/AKT signaling through MT1/MT2 receptors.

Dim Light at Night Disrupts the Sleep-Wake Cycle and Exacerbates Seizure Activity in Cntnap2 Knockout Mice: Implications for Autism Spectrum Disorders

This study shows that dim light at night increases seizure-like events and disrupts sleep in Cntnap2 knockout mice, with sex-specific effects.

Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus

This study identifies ZFHX3's role in regulating circadian gene expression in the SCN by mapping its genomic binding sites and analyzing transcriptomic changes in ZFHX3 mutants.

Expression of Non-Visual Opsins in the Green Anole Lizard (Anolis carolinensis)

This study identifies non-visual opsin expression in multiple tissues of the green anole lizard, highlighting tissue-specific patterns and evolutionary conservation.

Mitofusin 2 controls mitochondrial and synaptic dynamics of suprachiasmatic VIP neurons and related circadian rhythms including sleep

This study shows that mitofusin 2 regulates mitochondrial and synaptic dynamics in SCN VIP neurons, affecting circadian rhythms and sleep in mice.

Subunit shuffling dynamics in KaiC's central hub reveal the synchronization mechanism of the cyanobacterial circadian clock

The paper investigates subunit shuffling dynamics in KaiC's central hub, revealing how ATPase activity regulates this process in the cyanobacterial circadian clock.

Non-linear effects of evening light exposure on cognitive performance

This study examines how different levels of melanopic illuminance affect cognitive performance and workload, finding non-linear relationships with both positive and negative effects at moderate and extreme light levels.