M. Yu

Species packing and the latitudinal gradient in beta-diversity

The paper tests whether beta-diversity contributes to the latitudinal gradient in species richness by analyzing tree species data across East Asia.

Structural basis of TRPC4 regulation by calmodulin and pharmacological agents

The paper reports structures of TRPC4 in complex with inhibitors, activators, and calmodulin, revealing how ligand binding and calmodulin interaction regulate the channel's conformation.

Biodegradation of polyester polyurethane by Aspergillus flavus G10

This study investigates the biodegradation of polyester polyurethane by Aspergillus flavus G10 using multiple analytical techniques and identifies conditions that enhance degradation.

Phenotype Spectrum reflects Synergies among the Cell Architecture over Stages of the Cell Cycle

The paper investigates the relationship between cell cycle phases and migratory behaviors in NIH 3T3 fibroblasts, showing synergies between cell cycle regulators and migration.

Inhibition of 2-Hydroxyglutrate Elicits Metabolic-reprograming and Mutant IDH1 Glioma Immunity

This study shows that inhibiting 2-hydroxyglutarate in mIDH1 gliomas with ATRX/TP53 inactivation improves survival and induces anti-tumor immunity through immunological memory and reduced T-cell exhaustion.

Predicting Metastasis with a Novel Biophysical Cell-Adhesion Force Technique

This paper introduces a novel bead-pipette assay to measure cell adhesion forces and demonstrates its effectiveness in distinguishing metastatic from non-metastatic cells.

Distinct trends in chemical composition of proteins from metagenomes in redox and salinity gradients

The paper analyzes protein composition trends in metagenomes across redox and salinity gradients, finding that salinity affects hydration states while redox gradients are better captured by carbon oxidation state differences.

Limited Environmental Serine Confers Sensitivity to PHGDH Inhibition in Brain Metastasis

This study shows that brain metastases rely on PHGDH-mediated serine synthesis due to limited environmental serine, making them sensitive to PHGDH inhibition.

A hydrogen dependent geochemical analogue of primordial carbon and energy metabolism

This paper demonstrates that hydrothermal minerals catalyze CO2 fixation with H2 under alkaline conditions, producing organic compounds similar to the acetyl-CoA pathway.

Diversity and Structural Variability of Bacterial Microbial Communities in Rhizocompartments of Desert Leguminous Plants

This study examines bacterial community diversity and structure across different rhizocompartments of desert leguminous plants, revealing significant niche-driven variability and core microbiomes.

Identification of Escherichia coli ClpAP in regulating susceptibility to type VI secretion system-mediated attack by Agrobacterium tumefaciens

The paper identifies ClpAP in E. coli as a factor influencing susceptibility to T6SS-mediated killing by A. tumefaciens.

Widespread positive selection for mRNA secondary structure at synonymous sites in domesticated yeast

The paper investigates positive selection for mRNA secondary structure at synonymous sites in domesticated yeast, finding that GC content and structure influence translational efficiency and adaptation.

Structure of the tripartite motif of KAP1/TRIM28 identifies molecular interfaces required for transcriptional silencing of retrotransposons

This study identifies molecular interfaces in KAP1's RBCC motif critical for self-association and KRAB binding, essential for retrotransposon silencing.

Modulating pathogenesis with Mobile-CRISPRi

The paper demonstrates the use of Mobile-CRISPRi to knock down virulence life-style genes in a murine infection model, showing reduced virulence in mice.

Quantitative modelling predicts the impact of DNA methylation on RNA polymerase II traffic

The paper uses mathematical modeling and experimental analysis to show MeCP2 creates 'slow sites' in gene bodies, affecting RNA polymerase II traffic and gene expression.

Characteristics of executive control network function based on a lateralized version of the ANT-R test in athletes from open skill sports: An fNIRS study

This study uses fNIRS to compare executive control network function in interceptive and strategic athletes, finding differences in accuracy, reaction time, and brain activity in the right inferior frontal gyrus.

Microplate Assay for Denatured Collagen using CollagenHybridizing Peptides

This paper develops a microplate assay using collagen hybridizing peptides to quantify denatured collagen, showing it is reliable and efficient compared to existing methods.

Host protein CD63 enhances viral RNA replication by interacting with human astrovirus nonstructural protein nsP1a/4