L. Wang

This study shows that m6A RNA methylation reduces gene expression variability and impairs reproductive thermotolerance in Arabidopsis under heat stress.

This study identifies key genes regulating mesophyll conductance in drought-resistant rice under severe drought by comparing gene expression and photosynthetic processes between two rice cultivars.

This study identifies six thiolases in Aspergillus oryzae and shows their roles in fatty acid and ergosterol biosynthesis, with some exhibiting dual functionality.

This study shows that m6A RNA methylation sequesters transposon RNA in stress granules, preventing mobilization, and that demethylation by AtALKBH9B allows transposon activation.

This study maps single-cell transcriptomes and T cell repertoires in Behcet's disease to identify immune mechanisms and T cell trajectories in vascular and dermal manifestations.

This paper develops a bifunctional reaction system to simultaneously resolve lipid positional and geometric isomers using mass spectrometry, revealing structural patterns in bacteria and tracking changes in mouse brain ischemia.

This study shows that a UB-612 booster vaccine significantly increases neutralizing antibodies against SARS-CoV-2 variants, including Omicron, with estimated 95% efficacy against the ancestral strain.

This study identifies POU2AF2 as a co-activator of POU2F3 in SCLC, showing it maintains chromatin accessibility and enhancer activity essential for tuft cell marker expression.

The paper shows hypoferremia reduces neutrophil production and alters their function, while increasing NETosis, and suggests targeting hepcidin could modulate innate immunity.

The paper identifies Lnc956 as a non-coding RNA that forms a complex with TRIM28 and HSP90B1 to prevent replication fork collapse and maintain genomic stability in mouse embryonic stem cells.

This study shows that Piezo2 is essential for mechanical pain sensitization in osteoarthritis, as Piezo2-deficient mice are protected from mechanical hypersensitivity in two models.

This study evaluates the cobas(R) HBV RNA assay's performance in detecting and quantifying circulating HBV RNA in chronic HBV patients, showing high sensitivity and minimal interference from HBV DNA.

This study shows that FER-mediated phosphorylation of GRP7 promotes phase separation, enhancing Arabidopsis temperature resilience by forming stress granules that inhibit translation during temperature shifts.

This study identifies NKG2A and HLA-E as an alternative immune checkpoint axis in bladder cancer, showing NKG2A+ CD8 T cells can bypass HLA-ABC loss through TCR-independent cytotoxicity.

This study shows how natural selection rapidly reshapes developmental gene regulatory networks in sea urchins with divergent life histories, revealing evolutionary changes in gene regulation and chromatin status.

This study shows NAC1 suppresses regulatory T cell-mediated tolerance by deacetylating and destabilizing FoxP3, leading to autoimmunity, and suggests targeting NAC1 could treat autoimmune disorders.

This study investigates the association between RSV genetic variations and disease severity in infants, finding significant links between phylogeny and specific protein variations in different subtypes.

This study investigates enrofloxacin's ability to cross the blood-brain barrier in crucian carp and its impact on brain injury markers.

This study evaluates the neutralization efficacy of antibodies against SARS-CoV-2 Omicron and other variants, finding that antibody 8G3 maintains broad neutralizing activity while EUA antibodies lose effectiveness.

This study shows that eosinophils migrate to the lungs early after Mycobacterium tuberculosis infection in mice and macaques, mediated by GPR183 and Ch25h, independent of CCR3.

The paper uses super-resolution microscopy and a fluorescent probe to analyze lysosome spatial organization relative to mitochondria, revealing changes in distance distribution patterns during autophagy and linking lysosome positioning to mitochondrial health.

This study compares the virological characteristics of SARS-CoV-2 BA.2 and BA.1 variants, finding BA.2 has higher transmissibility, different antigenicity, greater replicative capacity, and higher pathogenicity in hamsters.

This study develops a sequence-based functional metagenomics approach to discover novel CopA genes in environmental microbiomes, identifying 175 new sequences with functional validation.

This study shows that laminin and nidogen in the basal lamina form complexes with the MEC-4 channel to enable touch sensation in C. elegans.

This study examines reassortment dynamics of influenza A virus in guinea pigs, ferrets, and swine, finding reassortment is common but more frequent in ferrets and guinea pigs than swine, with spatial compartmentalization observed.

This study shows that BA.2 causes stronger antibody evasion than BA.1, particularly in SARS convalescents, and identifies key mutations responsible for this escape.

This study compares Reelin+ HSCs and Desmin+ HSCs in liver fibrosis using fate tracing, showing differences in activation, migration, and proliferation in response to cholestatic and hepatotoxic injuries.

This study identifies NDP52's role in modulating RNA Polymerase II transcription by altering DNA conformation through direct dsDNA binding and interactions with chromatin regulators.

This study constructs multiscale models of SARS-CoV-2 using coarse-grained molecular dynamics simulations and experimental data, revealing dynamic behavior of membrane proteins and lipid interactions.