Z. Wang

The paper uses DC-iDEP to isolate insulin vesicles from pancreatic β-cells and identifies distinct distribution patterns in response to glucose stimulation.

This study investigates the inactivation effect of UVCLED on Acinetobacter baumannii, showing that high irradiance improves sterilization efficiency and causes distinct structural and genomic damage.

The paper uses cryo-ET to identify structural changes in platelets during pre-acute myeloid leukemia, suggesting these changes could serve as an early diagnostic biomarker.

The paper shows that loss of SRSF1, a splicing factor, accelerates pancreatic cancer by disrupting homeostasis and enhancing KrasG12D-driven tumorigenesis.

The paper reveals TACAN is a homodimer with lipid-associated domains and suggests membrane lipids coordinate with the protein to sense mechanical signals.

The paper presents the first structure of native nebulin bound to thin filaments in sarcomeres, revealing interactions with actin and myosin conformations, and the molecular basis of nebulin's role in muscle function.

The paper identifies proteasome-associated HECT-type ubiquitin ligases that relay and process hormone-specific transcriptional activators, regulating their activity and stability.

The paper uses imaging spectroscopy to link aboveground vegetation properties with belowground soil processes in two grassland experiments, finding contrasting relationships based on ecosystem productivity and diversity.

This study identifies {Delta}7-DA as the endogenous ligand for Ss-DAF-12 in Strongyloides stercoralis and shows its potential as a therapeutic target when combined with ivermectin.

This study identifies pD345L as an ASFV protein that inhibits NF-κB signaling by blocking IKK kinase activity, providing insights into ASFV immune evasion mechanisms.

This paper introduces a gRNA-free RNA editing system called REWIRE that achieves high editing efficiency and low off-target effects in human and mouse cells.

The paper describes a framework using targeted phage display to identify conserved epitopes on the SARS-CoV-2 Spike protein for universal vaccine development.

The paper identifies how EPS1, a BAHD acyltransferase, evolved to catalyze a unique lyase reaction in SA biosynthesis in Brassicaceae plants through active site reconfiguration.

This study uses scRNA-seq to analyze lung cellular heterogeneity and host response during severe influenza infection in mice, identifying key immune and non-immune cell changes and communication dynamics.

This study investigates how calreticulin exon-9 INDEL mutations affect calcium signaling and contribute to essential thrombocythemia through structural changes and reduced calcium binding.

This study examines memory B cell evolution 5 months after mRNA vaccination in naive individuals, finding increased neutralizing activity but no further breadth or potency, and higher overall plasma neutralizing potency compared to natural infection.

This study shows BTKi treatment reduces APOBEC3 expression in CLL B cells through enhancer regulation, linking BCR signaling to genomic instability.

This study evaluates the neutralizing capacity and protective efficacy of human polyclonal IgG against SARS-CoV-2 variants in vitro and in a transgenic hamster model.

This study examines age-related cellular changes in the rotator cuff enthesis of rats, finding increased mineralization and reduced tenogenic and chondrogenic potential in aged cells.

This study shows that exosomal miR-328 from lung adenocarcinoma cells promotes osteoclastogenesis by targeting Nrp2 and suggests its inhibitors as a potential treatment for bone metastasis.

The paper uses phylogenetic network analysis to show that the SARS-CoV-2 VOC202012/01 variant originated through recombination, not step-wise mutations.

This study identifies how AMIGO1 modulates Kv2.1 voltage sensor movements and conductance activation by destabilizing the earliest resting state.

This paper introduces a self-immolative linker that restores activity to an inactive heparanase probe, enabling facile development of activatable imaging probes.

This study shows vitamin D reduces mitochondrial ROS and oxidative phosphorylation while enhancing stress tolerance and anti-cancer responses in osteosarcoma cells.

This study identifies two molecular subtypes of gastric cancer using multi-omics data and clustering algorithms, showing distinct survival outcomes and therapeutic responses.

This paper develops a machine learning model using Raman spectroscopy to accurately identify viruses, achieving high accuracy in classifying virus types and subtypes.

This study shows that Glycerol monolaurate improves intestinal barrier and immunity in broilers by reducing inflammation, enhancing antioxidant balance, and modulating gut microbiota.

This study shows benzydamine enhances tetracycline antibiotics' effectiveness against drug-resistant bacteria by disrupting membrane potential and increasing drug uptake.

The paper shows liver endothelial cells promote HER3-mediated survival in KRAS wild-type and mutant colorectal cancer cells through secreted factors, suggesting HER3 as a therapeutic target regardless of KRAS mutation status.