Arsenic contamination and mitigation

Aquaporin-9 and aquaporin-10 but not aquaporin-3 confer susceptibility to dimethylarsinic acid genotoxicity in human cells

The paper shows that AQP9 and AQP10 increase DMA(V)-induced DNA damage in human cells, while AQP3 and AQP7 do not, indicating their role in arsenic genotoxicity.

Aquaporin-3 amplifies arsenite genotoxicity as a dose-dependent gene-by-environment interaction in human cells

This study shows that AQP3 amplifies arsenite-induced DNA damage in a dose-dependent manner, indicating a gene-by-environment interaction that influences genotoxicity.

Genome-resolved metatranscriptomic analysis of arsenic demethylation and detoxification in a methanogenic rice paddy soil

This study uses genome-resolved metatranscriptomics to investigate arsenic demethylation and detoxification pathways in methanogenic rice paddy soil, linking methyltransferase gene expression to microbial processes.

Role of Nutritional Status on Arsenic Toxicity in Daphnia pulex: A Transcriptomic Perspective on Individual and Interactive Effects

This study examines how nutritional status affects arsenic toxicity in Daphnia pulex through transcriptomic analysis, revealing that phosphorus limitation has a greater impact than food quantity.

Amaranthus viridis-derived phytopriming reprograms redox homeostasis and limits arsenic accumulation in rice

This study shows that Amaranthus viridis extract reduces arsenic accumulation in rice by improving redox homeostasis and limiting arsenic uptake and translocation.

Home is Where the Heterogeneity Is: Housing Facility-level Differences in the Gut Microbiome and Metabolic Phenotype Confound Arsenic Effects on Glucose Homeostasis in Male Mice

This study shows that housing facility differences in gut microbiome and metabolism confound arsenic effects on glucose homeostasis in mice, with facility explaining more variance than arsenic exposure.

Arsenic-Driven Trafficking of ACR3 Transporters Is Conserved across Plant Lineages

The paper investigates ACR3 transporter trafficking in plants, showing conserved mechanisms linking arsenic sensing to subcellular localization across lineages.

Alleviation of arsenic (III) toxicity in rice (Oryza sativa L.) by employingmonolayer protected modified silver nanoadsorbent: Insights into growthreconditioning with antioxidant defence

This paper demonstrates that a silver nanoadsorbent reduces arsenic (III) toxicity in rice plants by improving growth and antioxidant defenses.

Prenatal Arsenic Exposure and Gene Expression in Fetal Liver, Heart, Lung, and Placenta

This study examines gene expression changes in fetal liver, heart, lung, and placenta after prenatal arsenic exposure in mice, identifying immune-related pathway alterations and reduced Gbp3 expression in female placentas.

Conserved Molecular Responses to Arsenite Exposure in Drosophila melanogaster

This study identifies conserved molecular responses to arsenite exposure in Drosophila, revealing shared pathways with human arsenic-related diseases.

Engineered probiotics that sequester arsenite in a mouse gastrointestinal system

This paper engineers probiotics to sequester arsenite in the mouse gut, reducing its systemic absorption and demonstrating the feasibility of using living therapeutics for environmental toxin interception.

Methanotrophic acetogenesis drives a novel pathway of arsenic mobilization in reducing groundwaters

The paper identifies a microbial pathway where methane oxidation produces acetate, which then drives Fe(III) and As(V) reduction, leading to arsenic mobilization in groundwater.

Construction of a novel 3D urinary bladder mucosa model and its application in toxicity assessment of arsenicals

This paper constructs a 3D urinary bladder mucosa model and uses it to assess the toxicity of arsenicals, showing dose-dependent cytotoxic effects and potential carcinogenic mechanisms.

Molecular Insights Into PGPR-Biochar-Mediated Arsenic Detoxification and Nutritional Enhancement in Rice Rhizospheres

This study shows that combining rice biochar and PGPR reduces arsenic bioavailability and enhances rice growth in contaminated soils.

Early-life Exposure to Arsenic Primes the Offspring to Increased Asthma Risk: Transcriptome and Epigenome Analysis

This study shows that maternal exposure to low-level inorganic arsenic increases offspring asthma risk through epigenetic changes, including miR-101c downregulation and TGFβ pathway dysregulation.

Developmental Immunotoxicity of Low-dose Inorganic Arsenic Reprograms Macrophages Inducing Tumor-promoting Phenotypes

This study shows that low-dose inorganic arsenic exposure reprograms macrophage polarization, increasing tumor-promoting activity and altering immune responses in a sex-dependent manner.

The Effect of Arsenic on Mitochondrial Fatty Acid Metabolism via Inhibition of Carnitine Palmitoyltransferase 1B and Choline Kinase Beta in C2C12 Cells

This study shows arsenic inhibits mitochondrial fatty acid metabolism in C2C12 cells by reducing key enzymes and mitochondrial DNA, leading to muscle damage.

Mouse nephron formation is impaired by moderate-dose arsenical exposure

This study shows that moderate-dose arsenical exposure during mouse kidney development impairs nephron formation and increases the risk of chronic kidney disease.

Aquifer microbial communities are highly variable in response to thermal arsenic mobilization

The paper examines how microbial communities in aquifers change in response to thermal arsenic mobilization and identifies potential biogeochemical roles of microbes in arsenic cycling.

Arsenic-sensing domain controls ACR3 transporter trafficking and function in Marchantia polymorpha

This study identifies an arsenic-sensing domain in MpACR3 that regulates its trafficking and function, revealing a plant-specific adaptation to arsenic toxicity.

Molecular and cell phenotype programs in oral epithelial cells directed by co-exposure to arsenic and smokeless tobacco

This study investigates the molecular and cellular responses of oral epithelial cells to arsenic and smokeless tobacco exposure using multi-omics analysis and identifies key mechanisms linked to cancer progression.

Gestational arsenite exposure alters maternal postpartum heart size and induces Ca2+ handling dysregulation in cardiomyocytes

This study shows that gestational arsenic exposure increases postpartum heart size and disrupts calcium handling in cardiomyocytes.

Microbiota-dependent in vivo biotransformation, accumulation, and excretion of arsenic from arsenobetaine-rich diet

This study shows that gut microbiota in mice transform arsenobetaine into toxic arsenic species, affecting its accumulation and excretion.

Suspect screening-data independent analysis workflow for the identification of arsenolipids in marine standard reference materials

This paper presents a suspect screening workflow with data independent analysis to identify arsenolipids in marine standard reference materials, identifying several arsenolipid compounds with high confidence.

Arsenite methyltransferase 3 regulates hepatic energy metabolism which dictates the hepatic response to arsenic exposure

This paper shows that As3mt regulates hepatic energy metabolism independently of arsenic detoxification, leading to mitochondrial dysfunction and fatty liver in zebrafish mutants.

Differential metabolism of arsenicals regulates Fps1-mediated arsenite transport

The paper shows how yeast cells differentiate between arsenate and arsenite by metabolizing them to regulate the Fps1 channel through distinct cysteine modifications and Hog1 signaling.

Early low-level developmental arsenic exposure impacts mouse hippocampal synapticfunction

This study examines the effects of early developmental arsenic exposure on hippocampal synaptic function in mice, finding decreased basal transmission and increased long-term potentiation.

Dendritic cell CX3CR1 and macrophages F4/80 play a central role in between gut micro biome and inflammation in Arsenic induced mice

This study shows chronic arsenic exposure disrupts gut microbiota and increases inflammation by altering immune markers like F4/80 and CX3CR1 in mice.

Analysis of co-regulated abundance of genes associated with arsenic and phosphate metabolism in Andean Microbial Ecosystems

The paper analyzes the abundance of arsenic and phosphate metabolism genes in microbial ecosystems to show their co-regulation under environmental conditions.

A simple chromogenic whole-cell arsenic biosensor based on Bacillus subtilis

The paper describes a whole-cell arsenic biosensor based on Bacillus subtilis that detects arsenate at levels below the WHO safe limit.