Y. Li

This paper uses spatial single-cell omics to analyze PDAC tumors and microenvironment, identifying key populations and interactions that may inform treatment strategies.

This study examines how positive and negative emotions affect false memory using EEG, finding higher false memory rates and distinct brain activation patterns in the positive emotion group.

This study shows that IL-17 signaling in renal tubular epithelial cells drives antibody-induced glomerulonephritis, and Regnase-1 limits this inflammation by inhibiting IL-17 target genes.

This study compares the performance of Autof MS 1000 and Bruker MALDI-TOF MS systems in identifying Nocardia species using clinical isolates and sequence analysis as a reference.

This paper demonstrates that iRGD-liposomes enhance the delivery and efficacy of AR-ASO in treating prostate cancer and bone metastasis without increasing toxicity.

This study evaluates SARS-CoV-2 entry mediated by ACE2 from 11 species, finding that pangolin and some mammals allow entry, while others do not, suggesting complex cross-species transmission potential.

This study shows Hsp70 chaperones TDP-43 in liquid-like phase, preventing its aggregation and maintaining dynamic nuclear bodies under stress.

This study compares fucoidan and 2'-Fucosyllactose in inhibiting human norovirus replication in zebrafish larvae, finding only fucoidan effectively inhibits replication.

This study shows that complex natural organic carbon sources better enrich diverse subsurface bacteria than simple organic sources.

This study identifies ALC1 as a key determinant of PARPi toxicity in HR-deficient cells by linking PARP-dependent chromatin remodeling to PARPi response.

This study finds a significant association between Kaposi's Sarcoma Herpesvirus (KSHV) infection and osteosarcoma in the Xinjiang Uyghur population, identifying KSHV as a potential risk factor and a newly identified viral-associated cancer.

This study shows ORMDL1 is upregulated in colorectal cancer and associated with better patient survival.

This study identifies DREB2B as a negative regulator of seed vigor through the ABA pathway in Arabidopsis and cotton, interacting with RCD1 and synergizing with ABI3.

This paper introduces DEAS, a simulator that predicts crop latitude adaptation using florigen gene expression, enabling faster breeding for climate-resilient crops.

The paper identifies Cop1 as a modulator of macrophage infiltration and cancer immunotherapy in TNBC by using in vivo CRISPR screens and multi-omics analyses.

This study identifies abundant and diverse circRNAs from SARS-CoV-2, SARS-CoV, and MERS-CoV, revealing a novel type of circRNA distinct from DNA-encoded circRNAs.

This study shows that calorie restriction affects gut microbiome, which in turn influences metabolism, hormones, and brain function in obese individuals.

This study shows that loss of Tmem30a in podocytes causes albuminuria and glomerulosclerosis in mice, with reduced TMEM30A expression observed in human podocytopathies.

The paper shows that serine palmitoyltransferase (SPT) modulates intestinal stem cell homeostasis by promoting stemness through sphingolipid production and PPAR-alpha activation, linking diet to cancer risk.

The paper identifies increased levels of specific non-HLA autoantibodies in kidney transplant patients with antibody-mediated rejection.

The paper shows that primary cilia in pancreatic β cells enhance insulin receptor signaling and mediate negative feedback during glucose-stimulated insulin secretion.

This study develops and tests a recombinant RBD-Fc vaccine against SARS-CoV-2, showing protection in non-human primates and mice.

The paper investigates the role of miR-129-5p in reversing CCl4-induced hepatic fibrosis by targeting PEG3 and the NF-κB pathway, though the manuscript has been withdrawn.

This study identifies keratin 1-based epidermal green autofluorescence as a biomarker for non-invasive assessment of inflammation and oxidative stress levels in the body.

This study shows that supplementing nutrients like L-leucine and insulin/sugar can induce appendage regeneration across three species: cnidarians, insects, and mammals.

This study develops and tests bat influenza-based live attenuated vaccines for pigs, showing they reduce viral replication and lesions without causing vaccine-associated enhanced respiratory disease.

The paper analyzes public data to show that PDCD1 and CD274 expression in T cells and macrophages correlates with COVID-19 severity.

This study shows the bone microenvironment enhances metastatic potential of cancer cells, enabling further dissemination and multi-organ metastasis, independent of genetic selection.