P. Wang

Magnetogenetic cell activation using endogenous ferritin

This paper develops a magnetogenetic method using anti-ferritin nanobodies and a benchtop electromagnet to activate cells in vivo, improving glucose tolerance in mice.

A CMOS-based highly scalable flexible neural electrode interface

This paper develops a scalable flexible neural interface to connect high-density electrode arrays to silicon chips, demonstrating its effectiveness in measuring neural activity in a mouse model.

Epidermal Growth Factor potentiates EGFR(Y992/1173)-mediated therapeutic response of triple negative breast cancer cells to cold atmospheric plasma-activated medium

The paper shows EGF enhances TNBC cells' response to CAP-activated medium by activating specific EGFR phospho-tyrosines and increasing ROS levels.

Bearskin2 mediates the coordinated secretion of xylogalacturonan and root cap polygalacturonase in Arabidopsis border-like cells

This study shows that BRN2 controls XGA synthesis, which facilitates RCPG export and BLC separation in Arabidopsis.

SnRK2-mediated phosphorylation of SIZ1 enhances global SUMOylation under osmotic stress in Arabidopsis

This study identifies SnRK2-mediated phosphorylation of SIZ1 as a mechanism enhancing SUMOylation under osmotic stress in Arabidopsis.

Tbx5 maintains atrial identity by regulating an atrial enhancer network

This study shows Tbx5 maintains atrial identity by regulating an atrial enhancer network through chromatin accessibility and looping.

A single amino acid substitution in MdLAZY1A dominantly impairs shoot gravitropism in Malus

This study identifies a single amino acid substitution in MdLAZY1A that causes weeping growth in apple by impairing gravitropism.

Cancer mutations rewire the RNA methylation specificity of METTL3-METTL14

The paper shows that a cancer mutation in METTL14 changes RNA methylation specificity, promoting oncogenesis by altering gene expression without increasing global m6A levels.

Transcription factor GLK2 regulates key steps of anthocyanin biosynthesis to antagonize photo-oxidative stress during greening of Arabidopsis seedlings

Potentiation of host defense through sRNA packaged in OMVs of Xanthomonas oryzae pv. oryzicola

This study identifies Xosr001, an sRNA packaged in OMVs of Xoc, as a mediator of stomatal immunity in rice by modulating OsJMT1 and MeJA levels.

Association of NOTCH3 with Elastic Fiber Dispersion in the Infrarenal Abdominal Aorta of Cynomolgus Monkeys

The paper examines regional heterogeneity in aortas of cynomolgus monkeys, finding increased NOTCH3 and dispersed elastic fibers in the infrarenal region.

A proximity-dependent biotinylation map of cytosol-facing organelle outer membrane proteome in living Arabidopsis cells

The paper develops an OM proximity labeling system to map the proteome of cytosol-facing outer membranes in Arabidopsis cells and identifies potential receptors for protein translocation and organelle communication.

A regulatory circuit involving the NADH dehydrogenase-like complex balances C4 photosynthetic carbon flow and cellular redox in maize

This study investigates the role of the NDH complex in maize by analyzing mutants, finding it regulates carbon flow and redox balance in C4 photosynthesis.

Neutralization of SARS-CoV-2 BQ.1.1 and XBB.1.5 by Breakthrough Infection Sera from Previous and Current Waves in China

This study assesses neutralization of SARS-CoV-2 Omicron subvariants by sera from different vaccination and breakthrough infection cohorts, finding that BQ.1.1 and XBB.1.5 show strong neutralization evasion.

Three-dimensional imaging and quantification of mouse ovarian follicles via optical coherence tomography

This study uses SD-OCT to identify and quantify ovarian follicles in mice, showing agreement with histology and improved image contrast for follicle analysis.

Decomprolute: A benchmarking platform designed for multiomics-based tumor deconvolution

Decomprolute benchmarks multi-omic tumor deconvolution algorithms using proteogenomic data from CPTAC to improve reproducibility and reusability.

Accurate and Rapid Detection of Peritoneal Metastasis from Gastric Cancer by AI-assisted Stimulated Raman Cytology

This paper develops an AI-assisted stimulated Raman cytology method to detect peritoneal metastasis in gastric cancer with high accuracy and speed.

Interplay between acetylation and ubiquitination of imitation switch chromatin remodeler Isw1 confers multidrug resistance in Cryptococcus neoformans

This study identifies a regulatory axis involving acetylation and ubiquitination of Isw1 in Cryptococcus neoformans that controls multidrug resistance.

cpSRP54 and FtsH cooperate thylakoid membrane associated proteostasis during de-etiolation in Arabidopsis thaliana

The paper shows cpSRP54 and FtsH work together in thylakoid membrane protein quality control during de-etiolation in Arabidopsis, and provides a trackable marker for monitoring their activities.

Flow-induced mechanical coupling between perinuclear actin cap and nucleus governs spatiotemporal regulation of YAP transport

This study investigates how flow-induced mechanical forces regulate YAP nucleocytoplasmic transport through actin cap formation and nuclear stiffness changes, revealing a unified mechanism linking mechanical stimulation to transcriptional regulation.

Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes.

This study introduces disulfides into SARS-CoV-1 spike protein to stabilize locked conformations, revealing conserved structural features with SARS-CoV-2.

Impacts of Biostimulation and Bioaugmentation on Woodchip Bioreactor Microbiomes

This study evaluates how bioaugmentation and biostimulation affect microbiomes and nitrate removal in woodchip bioreactors under cold conditions.

HY5 regulates GLK transcription factors to orchestrate photomorphogenesis in Arabidopsis thaliana

The paper shows HY5 regulates GLK transcription factors to control chloroplast development and hypocotyl elongation during light-induced seedling development in Arabidopsis.

ZNF251 haploinsufficiency confers PARP inhibitors resistance in BRCA1-mutated cancer cells through activation of homologous recombination

This study identifies ZNF251 haploinsufficiency as a mechanism conferring PARP inhibitor resistance in BRCA1-mutated cancer cells through RAD51-mediated homologous recombination.

Depletion of collagen IX alpha2 interferes osteochondral homeostasis of the knee joint which ultimately causing osteoarthritis-like articular cartilage damage

This study shows that Col92 deficiency in mice leads to osteochondral homeostasis disruption and osteoarthritis-like cartilage damage in the knee joint.

Brassinosteroid gene regulatory networks at cellular resolution

The paper identifies BR-responsive gene expression in Arabidopsis root cells using single-cell RNA-sequencing and reveals HAT7 and GTL1 as transcription factors regulating cell elongation.

Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution

The paper shows that convergent evolution of Omicron variants evades antibodies from BA.5 infections while maintaining ACE2 binding, driven by immune imprinting.

IL-33 Involved in the Progression of Liver Fibrosis Through Innate Immunity Cells (MΦ) Regulated by ICOS/ICOSL Signaling in Early Stage of Mice Schistosomiasis

The study investigates how ICOS/ICOSL signaling regulates macrophage polarization and IL-33's role in liver fibrosis progression in mice with schistosomiasis.

Mapping the adaptor protein complex interaction network in Arabidopsis identifies P34 as a common stability regulator

The paper maps AP complex interactions in Arabidopsis, identifying P34 as a stability regulator of clathrin-mediated endocytosis and post-Golgi trafficking.

The microtubule-associated protein SlMAP70 interacts with SlIQD21 and regulates fruit shape formation in tomato

This study identifies SlMAP70 as a regulator of tomato fruit shape by interacting with SlIQD21 and modulating microtubule organization during fruit development.