development & morphogenesis

A single UV-C pulse modulates Gibberellin homeostasis and Plant Development in Arabidopsis

A single UV-C pulse alters gibberellin homeostasis in Arabidopsis, initially reducing GA12 and GA4 but later increasing GA4, leading to enhanced growth and fertility.

Butterfly egg plasticity in physiologically and reproductive relevant traits: adaptation to climate?

The paper examines egg pore morphology and traits in Pieris butterflies, finding variation linked to climate and suggesting dynamic adaptation.

Selectivity and dynamics of VAP family tether exchange across membrane contact sites

The paper investigates VAP family tether selectivity and dynamics at membrane contact sites, revealing distinct MCS footprints and compensatory mechanisms in cellular homeostasis.

An INSR-BECN1-KIAA0825 complex prevents hepatocytic insulin receptor secretion via extracellular vesicles against monogenic diabetes

This study identifies an INSR-BECN1-KIAA0825 complex that regulates INSR trafficking and function in hepatocytes, revealing how its disruption leads to monogenic diabetes.

Calcium signals at cytoneme contacts amplify Wnt/β-catenin signalling

This study shows that calcium signals at cytoneme contacts enhance Wnt/β-catenin signaling by stabilizing cell interactions and promoting signalosome formation.

Microtubule-associated protein 1S (MAP1S): a cardioprotective factor against post-myocardial infarction remodeling via apoptosis inhibition

This study shows that MAP1S protects the heart from post-MI apoptosis and remodeling by modulating the Hippo pathway in mice and cultured cardiomyocytes.

Evolutionary consequences of repeated loss of distyly in Linum

This study investigates the genomic consequences of repeated loss of distyly in Linum species, finding mixed evidence for relaxed selection and no clear genomic signature of selfing in homostylous lineages.

Colony morphogenesis regulates sporulation dynamics in bacterial biofilms

This study shows that colony expansion and sporulation dynamics in Bacillus subtilis biofilms are interdependent, with sporulation waves driving dormancy while non-sporulating cells maintain expansion.

Evolutionary patterns and repeated adaptive strategies of deep-sea anemones

This study analyzes genomes and transcriptomes of deep-sea anemones to reveal evolutionary patterns and adaptive strategies, finding repeated gene loss and molecular innovations in deep-sea species.

Invasion of new adaptive zones retains telltale signs of directional selection at macroevolutionary scales in mammals

The paper examines directional selection during adaptive zone transitions in mammals, finding elevated evolutionary rates in most cases compared to genetic drift.

How do body size and habitat fragmentation influence extinction in lizards? A long-term case study on artificial islands in the Brazilian Cerrado

This study examines how body size and habitat fragmentation affect lizard extinction in artificial islands created by reservoir flooding in the Brazilian Cerrado, finding that larger lizards are more vulnerable to extinction.

The atypical cadherin CELSR2 regulates distinct epithelial-mesenchymal states and oxidative phosphorylation in triple-negative breast cancer

This study identifies CELSR2 as a regulator of epithelial-mesenchymal plasticity and oxidative phosphorylation in triple-negative breast cancer, showing its role in shaping tumor heterogeneity.

Timing of DNA damage checkpoint adaptation predicts post-mitotic proliferative competence

The paper shows that the duration of DNA damage checkpoint arrest in budding yeast predicts post-mitotic proliferative competence after checkpoint adaptation.

Disruption of ultrasonic vocalizations with systemic administration of the non-competitive N-methyl-D-aspartate receptor antagonist MK-801 in adult male mice

This study examines how MK-801, an NMDA receptor antagonist, affects ultrasonic vocalizations and social behavior in male mice.

Linking drought strategy to climate of origin in a widespread C4 grass: hydraulic traits, xylem anatomy and stomatal behaviour in Themeda triandra

This study examines how hydraulic, stomatal, and anatomical traits in Themeda triandra relate to climate-of-origin, revealing two distinct drought strategies in different climatic conditions.

Osmo-hydraulic volume regulation ensures robust endothelial-to-haematopoietic transition

The paper identifies an osmo-hydraulic volume-regulation mechanism in haemogenic endothelial cells during endothelial-to-haematopoietic transition, showing it maintains cell integrity and HSPC production.

Paneth cell-derived Notch ligands DLL1 and DLL4 are crucial for intestinal crypt base stem cells.

This study shows that Paneth cell-derived Notch ligands DLL1 and DLL4 are essential for maintaining intestinal crypt base stem cells and their regeneration after injury.

A pH-dependent protein kinase cascade regulates divergent differentiation of Leishmania in the sand fly.

This study identifies a pH-dependent kinase cascade in Leishmania that regulates differentiation into infectious stages, revealing key pathways for acid adaptation and transmission.

The Effects of Prelimbic Inhibition on Time-based Intervention and Impulsive Choice

This study inhibits the prelimbic cortex in rats during FI training or impulsive choice tasks, showing increased impulsive choice and reduced self-control.

Tolerance to herbicide drift in "weedy" species is context-dependent and driven by early vegetative growth

This study examines how sublethal herbicide drift affects fitness of weed species across different agro-ecological contexts, finding context-dependent tolerance and links to developmental traits.

A Caulobacter hub taxon in the soybean root endosphere has a distinctive biofilm and engages in riboflavin-mediated mutualism with Bradyrhizobium

This study characterizes Caulobacter sp. RL271, a hub taxon in the soybean root endosphere, revealing its unique biofilm formation and riboflavin-mediated mutualism with Bradyrhizobium.

Extensive disruption of HoxA/D genes does not cause obvious defects in anterior vertebral patterning in zebrafish

This study shows that extensive disruption of HoxA/D genes in zebrafish does not cause visible defects in anterior vertebral patterning, suggesting HoxB/C genes play a more critical role.

Polymicrobial-driven NLRP6 inflammasome regulates IL-1β production and alveolar bone loss in a murine model of periodontitis

This study shows that NLRP6 inflammasome activation by polymicrobial interactions drives IL-1β production and alveolar bone loss in a mouse model of periodontitis.

RNase J2 is a specificity factor that governs global mRNA stability in Bacillus subtilis

This study shows RNase J2 in B. subtilis acts as a specificity factor for RNase J1, enhancing its degradation of mRNAs and influencing biofilm formation and swarming.

CRISPR herd immunity against a transducing phage underlies adaptive homologous recombination in resting bacteria

The paper shows that CRISPR-mediated herd immunity in E. coli promotes frequent homologous recombination by maintaining genetic diversity and enabling gene flow, enhancing adaptation rates.

Cooperation recruits corticolimbic projections and induces synaptic change in rats

This study shows that cooperation in rats activates specific corticolimbic pathways and leads to lasting synaptic changes and altered social behavior.

Resurrected in the field: benefits of rapid adaptation to historic drought seen mainly at the leading edge of a plant' species range

This study shows that drought-adapted plants have higher fitness at the leading edge of their range but lower fitness at lower elevations, suggesting potential range contraction under climate change.

A mechanical model of multicellular remodelling in epithelial monolayers

This paper introduces a mechanical model to simulate subcellular and tissue remodelling in epithelial monolayers, showing how deformation history affects tissue recovery.

RICTOR regulates an interspecies crosstalk that influences longevity through a novel methionine cycle-mitophagy axis

This study identifies RICTOR as a regulator of dietary plasticity in C. elegans, showing it modulates longevity through a methionine cycle-mitophagy axis influenced by bacterial vitamin B12.

Mechanistic basis for the spatiotemporal assembly of the Bloom Syndrome complex on ultrafine DNA bridges

This study identifies how the BTRR complex assembles on ultrafine DNA bridges through SLiM recognition by RMI1-RMI2, revealing spatiotemporal regulation during DNA repair and segregation.