B. Yang

Mutations Affecting Polar Nuclei Number, Antipodal Cell Cluster Size, Cellularization, and Nuclear Localization in Maize Embryo Sacs

The paper identifies mutations affecting polar nuclei number, antipodal cell morphology, and nuclear localization in maize embryo sacs, linking these defects to auxin signaling and MAP65-3 function.

Comparing acute IOP-induced lamina cribrosa deformations pre-mortem and post-mortem

The paper compares acute IOP-induced lamina cribrosa deformations in monkeys pre-mortem and post-mortem, finding similar trends but smaller pre-mortem deformations overall with local variations.

Mapping global land sharing-sparing patterns between human and wildlife

The paper maps global land sharing-sparing patterns between humans and wildlife using human-nature indices and classifies lands into four categories based on biodiversity and human pressure.

A Peronophythora litchii RXLR effector PlAvh202 enhances plant susceptibility by destabilizing host SAMS

This study identifies PlAvh202, an RXLR effector from Peronophythora litchii, which enhances plant susceptibility by destabilizing SAMS and suppressing ethylene production.

SIC50: Determination of IC50 by an optimized Sobel operator and a vision transformer

SIC50 uses a vision transformer and Sobel operator to determine IC50 from phase-contrast images, validated with four drugs and 1536-well plates.

Molecular and structural characterization of lenalidomide-mediated sequestration of eIF3i

This study identifies the structural basis of lenalidomide-mediated eIF3i sequestration and links it to antiangiogenic effects and cellular phenotypes.

High-throughput nanopore sequencing of Treponema pallidum tandem repeat genes arp and tp0470 reveals clade-specific patterns and recapitulates global whole genome phylogeny

The paper uses nanopore sequencing to analyze repeat regions in T. pallidum genes, revealing clade-specific patterns that align with whole genome phylogeny.

A dolabralexin-deficient mutant provides insight into specialized diterpenoid metabolism in maize (Zea mays).

The paper identifies ZmKSL4 as the diterpene synthase for dolabralexin biosynthesis in maize and shows its role in root architecture under water deficit.

Re-emergence of Severe Acute Diarrhea Syndrome Coronavirus (SADS-CoV) in Guangxi, China, 2021

The paper identifies the re-emergence of SADS-CoV in pigs in Guangxi, China, through qPCR and metagenomic analysis, suggesting undetected circulation since 2019.

On-target inhibition of Cryptosporidium parvum by nitazoxanide (NTZ) and paclitaxel (PTX) validated using a novel MDR1-transgenic host cell model and algorithms to quantify on/off-target rates

The paper validates on-target and off-target effects of anti-Cryptosporidium drugs using a novel MDR1-transgenic host cell model and algorithms to quantify drug action contributions.

Development and application of an uncapped mRNA platform

The paper develops an uncapped mRNA platform and demonstrates its effectiveness in inducing immune responses and protein expression in vitro and in vivo.

habCluster: Identifying Geographical Boundary among Intraspecific Units Using Community Detection Algorithm in R

habCluster identifies geographical boundaries of intraspecific units using a community detection algorithm, showing good alignment with nature reserves for giant pandas.

Polarly localized WPR proteins interact with PAN receptors and the actin cytoskeleton during maize stomatal development

The paper identifies WPR proteins as polarly localized in maize subsidiary mother cells, which interact with PAN receptors and F-actin, and show defects in cell division and actin structure when mutated.

Reversable deformation of artificial cell colony for muscle behavior mimicry triggered by actin polymerization

This paper develops self-powered artificial cell colonies that mimic muscle behavior through actin polymerization and depolymerization, showing reversible deformation and collective contraction.

Link between aging and atheroprotection in Mif-deficient atherosclerotic mice

This study investigates how Mif deficiency affects atheroprotection in aging Apoe-/- mice, finding that atheroprotective effects diminish with age.

Microtubule-associated IQD9 guides cellulose synthase velocity to shape seed mucilage

This study identifies IQD9 and KLCR1 as MT-associated proteins that guide cellulose synthase velocity to shape seed mucilage architecture in Arabidopsis.

Zinc finger protein Zfp335 controls early T cell development and survival through beta-selection-dependent and -independent mechanisms

This study identifies Zfp335 as a transcription factor regulating T cell development by controlling TCRβ expression and cell survival through β-selection-dependent and -independent mechanisms.

Mitogen-activated protein kinases associated sites of tobacco REPRESSION OF SHOOT GROWTH regulates its localization in plant cells

This study identifies MAPK-associated phosphorylation sites in RSG that regulate its subcellular localization and function in tobacco.

Rapid quantification of tissue perfusion properties with a two-stage look-up table: a simulation study

This study introduces a two-stage look-up table method to rapidly and accurately quantify tissue perfusion properties using multispectral spatial frequency domain imaging.

On the use of facial and neck cooling to improve indoor occupant thermal comfort in warm conditions

This study evaluates two wearable face and neck cooling fans to improve indoor thermal comfort and reduce HVAC energy use in warm conditions.

Hyaluronidase-1-mediated glycocalyx impairment underlies endothelial abnormalities in polypoidal choroidal vasculopathy

This study identifies hyaluronidase-1 as a key driver of glycocalyx impairment in PCV BOECs, linking it to endothelial dysfunction and proposing it as a therapeutic target.

Real-time imaging of optic nerve head collagen microstructure and biomechanics using instant polarized light microscopy

This paper demonstrates that instant polarized light microscopy (IPOL) can visualize and quantify collagen morphology and architecture changes in the optic nerve head under dynamic loading.

Lamina cribrosa vessel and collagen beam networks are distinct

The paper quantifies the spatial relationship between vascular and collagen networks in monkey lamina cribrosa, finding they are distinct with most beams lacking vessels and many vessels outside beams.

Synergistic interaction of hyposalinity stress with Vibrio infection causes mass mortalities in oysters by inducing host microflora imbalance and immune dysregulation

This study shows hyposalinity stress and Vibrio infection synergistically cause oyster mortality by disrupting microbial balance and triggering immune dysregulation.

OsSWEET11b, a sixth leaf blight susceptibility gene involved in sugar transport-dependent male fertility

The paper identifies OsSWEET11b as a rice gene involved in male fertility and susceptibility to bacterial leaf blight, showing its role in sucrose transport and Xoo virulence.

Age-associated Senescent - T Cell Signaling Promotes Type 3 Immunity that Inhibits Regenerative Response

This study shows that age-related senescent T cells promote type 3 immunity, which inhibits tissue repair, and that blocking this pathway improves healing in older animals.

High-throughput production of functional prototissues capable of producing NO for vasodilation

This study develops a high-throughput method to produce functional prototissues that generate nitric oxide, inducing vasodilation in rat blood vessels.

The phosphatidylglycerol phosphate synthase PgsA utilizes a trifurcated amphipathic cavity for catalysis at the membrane-cytosol interface

This study reports the structures of S. aureus PgsA at two catalytic states, revealing the mechanism of phosphatidylglycerol biosynthesis and the impact of daptomycin resistance mutations.

Modular biosynthesis of plant hemicellulose and its impact on yeast cells

This study engineers yeast to produce tunable plant hemicellulose polysaccharides using chimeric CSLA enzymes, showing growth compatibility and variable cell size modulation.

Optimizing mechanostable anchor points of engineered lipocalin in complex with CTLA-4

The paper identifies optimal anchor points on an anticalin scaffold for enhanced binding strength with CTLA-4 using AFM-SMFS and computational modeling.