Stress Responses and Cortisol

Self-beneficial belief updating as a coping mechanism for stress-induced negative affect

The paper investigates how self-related belief updating helps manage stress-induced negative affect after social-evaluative stress, showing it improves recovery compared to physical stress or no stress.

Opioid-blunted cortisol response to stress is associated to increased negative mood and wanting of social reward

The paper examines how morphine affects cortisol response to stress and links it to changes in negative mood and social reward seeking in humans.

Brain preparedness: The proactive role of the cortisol awakening response

The paper investigates the cortisol awakening response (CAR) and its role in brain preparedness, finding that CAR predicts improved neural efficiency and working memory performance.

Impact of Fkbp5 x Early Life Adversity x Sex in Humanized Mice on Multidimensional Stress Responses and Circadian Rhythmicity

The paper investigates how FKBP5 genetic variants interact with early life adversity and sex to affect stress responses and circadian rhythms in humanized mice.

Norepinephrine and glucocorticoids modulate chronic unpredictable stress-induced increase in the type 2 CRF and glucocorticoid receptors in brain structures related to the HPA axis activation.

This paper investigates how chronic unpredictable stress affects CRF and glucocorticoid receptors in brain regions related to the HPA axis and finds that stress increases CRF2 and GR levels in specific brain areas.

Genomic Modules and Intramodular Network Convergency of Susceptibility and Resilience in Multimodeled Stress in Male Mice

The paper identifies convergent genomic modules in stress models of mice, revealing shared biological functions across different stress paradigms.

A severe form of maternal separation in rat consisting of nineteen-day 6-hour daily separation at unpredictable times minimally affects behavior across the lifespan

This study examines the long-term behavioral effects of a severe maternal separation paradigm in rats, finding minimal adverse outcomes across the lifespan.

The vagus nerve is critical for regulation of hypothalamic-pituitary-adrenal axis responses to acute stress

This study investigates the role of the vagus nerve in regulating HPA axis responses to acute stress using rat models.

Early life stress programming of NG2+ glia transcriptome alters functional properties of voltage gated sodium (Nav) channels and cognitive performance

This study shows that early life stress alters the transcriptome of NG2+ glia, increases Nav channel activity, and impairs cognitive performance in adulthood.

Dynamic behavioral and molecular changes induced by chronic stress exposure in mice

This study examines how chronic stress affects behavior and molecular markers in mice, showing gender-specific differences in molecular responses and behavioral outcomes.

Sexually divergent cortical control of affective-autonomic integration

This study investigates sex differences in how the infralimbic prefrontal cortex regulates stress responses and cardiovascular outcomes in rodents.

Subfield-specific Effects of Chronic Mild Unpredictable Stress on Hippocampal Astrocytes

This study examines how chronic mild unpredictable stress affects astrocyte density and morphology in different hippocampal subfields in mice, finding differential effects across subpopulations.

Reduced anterior cingulate cortex volume induced by chronic stress correlates with increased behavioral emotionality and decreased synaptic puncta density

Juvenile exposure to acute traumatic stress leads to long-lasting alterations in grey matter myelination in adult female but not male rats

This study shows that juvenile stress alters grey matter myelination in adult female rats but not males, highlighting sex-specific vulnerability during peri-adolescence.

Molecular roadmap of the healthy stress response in the mouse hippocampus

This study characterizes the molecular changes in the mouse hippocampus during the acute stress response using multiomic profiling and identifies rapid resolution of molecular events within 4 hours.

Circadian fluctuations in glucocorticoid level predict perceptual discrimination sensitivity

The paper shows that higher cortisol levels before a hearing test improve pitch discrimination in humans across different ages.

The co-chaperone Fkbp5 shapes the acute stress response in the paraventricular nucleus of the hypothalamus

This study investigates the role of Fkbp5 in the paraventricular nucleus of the hypothalamus in shaping the HPA axis stress response through genetic manipulations.

Odor Blocking Of Stress

The paper shows that certain odorants can block stress hormone responses to various stressors in mice by inhibiting hypothalamic neurons involved in stress signaling.

Chronic stress induces sex-specific functional and morphological alterations in cortico-accumbal and cortico-tegmental pathways

This study investigates how chronic stress affects male and female mice's cortico-accumbal and cortico-tegmental pathways, revealing sex-specific functional, morphological, and transcriptional changes.

Corticotropin-releasing factor distribution in the brain of the brown anole lizard

This study maps CRF cell and fiber distributions in the brown anole lizard brain, finding similarities with snakes, turtles, and mammals/birds, but also some unique features.

Chronic Psychosocial Stress and Experimental Pubertal Delay Affect Socioemotional Behavior and Amygdala Functional Connectivity in Adolescent Female Rhesus Macaques

This study examines how pubertal timing and chronic stress affect socioemotional behavior and amygdala connectivity in adolescent female macaques, finding overlapping and distinct neural effects.

An opponent process for alcohol addiction based on changes in endocrine gland mass

The paper proposes a mathematical model of opponent processes in alcohol addiction, linking changes in HPA gland mass to {beta}-endorphin secretion and addiction vulnerability.

Chronic Exposure to Glucocorticoids Induces Suboptimal Decision-Making in Mice

This study shows chronic glucocorticoid exposure impairs decision-making and cognitive functions in mice, with associated neurobiological changes in the prefrontal cortex.

Poly (I:C)-induced maternal immune activation modifies ventral hippocampal regulation of stress reactivity: prevention by environmental enrichment

This study shows that environmental enrichment prevents social behavior disruptions and HPA axis dysregulation caused by maternal immune activation in mice.

Hypothalamic glucocorticoid receptor in CRF neurons is essential for HPA axis habituation to repeated stressor

The paper shows that glucocorticoid receptors in CRF neurons are essential for HPA axis habituation to repeated stressors by modulating inhibitory tone and dampening activation.

Translatomic profiling of the acute stress response: It's a TRAP

The paper reanalyzes TRAP-seq data on acute stress response in hippocampal neurons, finding limited translational changes and no effect of sex or early life stress.

Threat-induced hippocampal connectivity fingerprints do not generalize to psychosocial stress

This paper tests if a machine learning model predicting stress from hippocampal connectivity generalizes to psychosocial stress, finding limited generalizability.

Age- and sex- dependent changes in locus coeruleus physiology and anxiety-like behavior in response to acute stress

Programming effects of peripubertal stress on spatial learning

This study shows that peripubertal stress slows adult spatial learning and is linked to corticosterone response adaptation, not peak levels, and affects emotional reactivity and hippocampal plasticity.

Severe childhood and adulthood stress associates with neocortical layer-specific reductions of mature spines in psychiatric disorders

The paper examines how severe childhood and adulthood stress affects dendritic spine density in the human orbitofrontal cortex, finding greater reductions in childhood stress.