B. Wang

A multipotent cell type from term human placenta

The paper identifies multipotent CDX2 cells from term human placentas that can differentiate into cardiovascular lineages and restore cardiac function in a mouse model.

Dynamic simulations of feeding and respiration of the early Cambrian periderm-bearing cnidarian polyps

This study simulates the feeding and respiration of early Cambrian cnidarian polyps using CFD to show how muscle contractions drive water flow, supporting hypotheses about ancestral medusozoan behavior.

Single cell RNA analysis uncovers the cell differentiation trajectories and functionalization for air breathing of frog lung

This study uses single-cell RNA sequencing to identify cell types and differentiation trajectories in frog lungs, revealing functionalization for air breathing and evolutionary insights.

Crystal structures reveal nucleotide-induced conformational changes in G motifs and distal regions in guanylate-binding protein 2

This study reveals how GDP binding induces conformational changes in GBP2's G domain and distal regions, leading to dimer-monomer transitions and functional regulation.

Concerted transformation of a hyper-paused transcription complex and its reinforcing protein

This paper reveals how RfaH activates virulence gene expression by transforming its structure and stabilizing paused transcription complexes through interactions with ops hairpins.

A mutation-mediated host shift drives Avian paramyxovirus type 1 evolution

This study identifies mutations in the P protein of Avian paramyxovirus type 1 that drive host shift from chickens to pigeons through enhanced degradation of LSm14A.

Sex-biased regulatory changes in the placenta of native highlanders contribute to adaptive fetal development

The paper compares placental transcriptomes and histology between native Tibetans and Han migrants, finding sex-biased expression divergence and adaptive histological changes in male-infant placentas.

Cell type-specific cis-regulatory divergence in gene expression and chromatin accessibility revealed by human-chimpanzee hybrid cells

The paper identifies cell type-specific cis-regulatory divergence in gene expression and chromatin accessibility using human-chimpanzee hybrid cells across six cell types.

Synchrony of Bird Migration with Avian Influenza Global Spread; Implications for Vulnerable Bird Orders

The paper uses phylodynamic analyses to link bird migration patterns with the global spread of HPAIV H5 clade 2.3.4.4, identifying vulnerable bird orders and highlighting Suliformes and Ciconiiformes as important in virus dispersal.

Evolutionary analysis of conserved non-coding elements subsequent to whole-genome duplication in opium poppy

This study analyzes the evolutionary patterns of regulatory and coding sequences in opium poppy following whole-genome duplication, showing rapid regulatory element evolution contributes to new phenotypes.

Contrastive Learning for Sleep Staging based on Inter Subject Correlation

This paper addresses cross-subject sleep staging by applying contrastive learning based on inter-subject correlation, achieving state-of-the-art performance.

Fortuitous Somatic Mutations during Antibody Evolution Endow Broad Neutralization against SARS-CoV-2 Omicron Variants

The paper identifies an antibody with broad neutralization against SARS-CoV-2 Omicron variants and shows how somatic mutations enhance its neutralization breadth and potency.

GraphComm: A Graph-based Deep Learning Method to Predict Cell-Cell Communication in single-cell RNAseq data

GraphComm predicts cell-cell communication in single-cell RNAseq data by integrating gene expression with protein interaction networks and spatial information.

A crucial role for dynamic expression of components encoding the negative arm of the circadian clock

This study identifies brd-8 as a circadian-regulated component of the NuA4 histone acetyltransferase complex that modulates frq expression and circadian rhythm in Neurospora.

Integrative identification of non-coding regulatory regions driving metastatic prostate cancer

This study identifies non-coding regulatory regions driving metastatic prostate cancer using an integrative computational and experimental approach.

Semiconductor augumented valuable chemical photosynthesis from Rhodospirillum rubrum and mechanism study

This paper constructs a Rhodospirillum rubrum-CdS biohybrid system and investigates its enhanced photosynthetic activity and electron transfer mechanisms.

Surf4 deficiency reduces intestinal lipid absorption and secretion and decreases metabolism in mice

This study shows that intestinal Surf4 deficiency reduces lipid absorption, secretion, and metabolism in mice, leading to weight loss and altered lipid levels.

Dynamics of vegetation cover and its driving factors in the Qinling-Daba Mountains on regional scale for 1986-2019

This study analyzes vegetation cover dynamics and driving factors in the Qinling-Daba Mountains from 1986 to 2019 using satellite data and spatial analysis.

Parallel genetic adaptation of Bacillus subtilis to different plant species

This study shows Bacillus subtilis adapts genetically to different plant hosts and alternating host regimes, revealing both parallel and species-specific evolutionary patterns.

FAN, the homolog of mammalian Apoptosis Antagonizing Transcription Factor AATF/Che-1 protein, is involved in safeguarding genome stability through the ATR induced pathway in Arabidopsis

This study identifies FAN, a homolog of AATF/Che-1 in Arabidopsis, as essential for genome stability through the ATR-induced DNA damage response pathway.

A toxic ankyrin cysteine protease effector RipBH of brown rot triggered autophagy-associated cell death

The paper identifies RipBH, a virulent type III effector from Ralstonia solanacearum, which induces autophagy-associated cell death and is essential for potato brown rot pathogenesis.

Proteomic-based stratification of intermediate-risk prostate cancer patients

The paper identifies an 18-protein signature from proteomic data to stratify intermediate-risk prostate cancer patients into low- and high-risk groups for biochemical recurrence.

Domains Required for FRQ-WCC Interaction within the Core Circadian Clock of Neurospora

The paper identifies three Asp/Glu clusters in FRQ essential for FFC-WCC interaction in Neurospora's circadian clock, showing that binding strength is required for clock function but not period length.

Inducible mismatch repair streamlines forward genetic approaches to target identification of cytotoxic small molecules

This study develops an inducible mismatch repair system to identify targets of orphan cytotoxins by screening for compound resistance mutations in engineered cell lines.

A novel order-level lineage of ammonia-oxidizing Thaumarchaeota is widespread in marine and terrestrial environments

The paper identifies a new AOA order, Nitrosomirales, widespread in marine and terrestrial environments, showing metabolic versatility and horizontal gene transfer.

CRB3 navigates Rab11 trafficking vesicles to promote γTuRC assembly during ciliogenesis

This study identifies CRB3's role in navigating Rab11 vesicles to promote γTuRC assembly during ciliogenesis and its regulation of Hh and Wnt signaling in tumorigenesis.

A megaprotein brake for aging and insulin-mTOR signaling

This study identifies LPD-3 as a megaprotein that regulates insulin-mTOR signaling and aging in C. elegans by modulating sphingolipid and insulin pathways.

Widespread mermithid nematode parasitism of Cretaceous insects

This study describes 16 new mermithid nematode fossils from mid-Cretaceous amber, revealing widespread parasitism of invertebrates and new host associations.

A COVID-19 DNA Vaccine Candidate Elicits Broadly Neutralizing Antibodies Against Multiple SARS-CoV-2 Variants Including the Currently Circulating Omicron BF.5, BF.7, BQ.1 and XBB

An ULK1/2-PXN mechanotransduction complex suppresses breast cancer cell migration

This study identifies ULK1/2 as regulators of PXN-dependent mechanotransduction in breast cancer cells, showing their role in inhibiting migration by modulating focal adhesion assembly.